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Popular Abstract in Swedish Jag har under min forskarutbildning vid Lunds tekniska högskola studerat proteiner med hjälp av en metod som kallas kärnmagnetisk resonans, NMR. I levande organismer regleras allt liv av tre typer av molekyler: DNA, RNA och proteiner. Den centrala dogmen i biokemi "DNA-RNA-Protein" innebär att den genetiska kod som ärvs i form av DNA och som finns i varje cell i kroppeThe general objective of the present thesis work was to examine 3-dimensional structure as well as the motional properties of two different types of two-domain proteins by solution-state NMR. One of the major tasks of this thesis work was to investigate the domain orientation of these molecules by employing residual dipolar couplings (RDC) which can be used as orientational restraints for increasi

The aim of this project was to investigate the work of paramedics and to realize the need for improvement in their practice by identifying possible means of enhancing their equipment. I began this project by conducting extensive research on the subject and sought to improve my understanding of the knowledge I gained from this by conducting a series of field studies. These field studies helped me t

Sexualbrotten är de brott som har genomgått störst förändringar genom historien och våldtäktsmål debatteras ofta i olika medier. Definitionen av våldtäkt har utvidgats flera gånger men trots att det är ett allvarligt brott och trots att andra grova brott i Brottsbalken har en oaktsamhetsreglering så kan en gärningsman dömas för våldtäkt endast ifall han haft uppsåt till handlingen. Frågan om att iSex crimes are those crimes that have undergone the greatest changes in history and rape cases are often debated in various media. The definition of rape has been extended several times but even though it is a serious crime and despite other serious crimes in the Penal Code has a negligence regulation a perpetrator can be sentenced for rape only if he had an intent to act. To introduce some kind o

Stock market movements forecast based on sentiment analysis is certainly a field worth investigating. Being able to build future investment strategies based on forecasted stock returns would be of tremendous importance for individual investors and high-frequency trading firms. This thesis aims to closely investigate the impact that tweet sentiments in Twitter have on stock market movements; it int

Reglerna i rättegångsbalken (1942:740) som reglerar användandet av sakkunnigbevisning har i princip inte förändrats sedan balken trädde ikraft på början av 1940-talet. Detta har skapat en slags obalans mellan hur rättsordningen föreskriver att sakkunnigbevisningen ska tillämpas och hur användandet av sakkunniga faktiskt ser ut i praktiken. Uppsatsen inleds med en historisk tillbakablick där blandThe rules in the Swedish Code of Judicial Procedure that regulates the use of expert evidence have not been revised since The Code entered into force in the early 1940s. This has created a sort of imbalance between how the legal system intends the rules on expert evidence to be applied and what the use of trial experts actually looks like in practice. The essay begins with a historical background

The purpose of this study was to psychometrically test a Swedish translation of The Shame Inventory, originally developed by Rizvi (2010). Another purpose was to investigate the link between shame and psychopathology and specifically to borderline personality disorder. The psychometric properties of the Swedish version of The Shame Inventory were investigated, as well as the ability of the instrum

Post-consolidation immunotherapy with histamine dihydrochloride and interleukin-2 has been shown to improve leukemia-free survival in acute myeloid leukemia in a phase III trial. For this study, treatment efficacy was determined among 145 trial patients with morphological forms of acute myeloid leukemia as defined by the French-American-British classification. Leukemia-free survival was strongly i

Genom Europakonventionen och regeringsformen tillförsäkras den enskilde ett flertal rättigheter. Varje medborgare åtnjuter bland annat skydd till frihet och personlig säkerhet samt till privat och familjeliv, sitt hem och sin korrespondens. Dessa friheter får begränsas genom lag under förutsättning att begränsningen tillgodoser ändamål som är godtagbara i ett demokratiskt samhälle. Att utreda brotThe Convention for the Protection of Human Rights and Fundamental Freedoms (ECHR) and the Swedish constitution guarantee everyone a number of civil rights. Every citizen has the right to respect for his private and family life, his home and his correspondence. These rights may be limited by law, presumed that these limitations have a righteous purpose in a democratic society. Investigating crimes

Apidaecin 1b (Api), the first characterized Type II Proline-rich antimicrobial peptide (PrAMP), is encoded in the honey bee genome. It inhibits bacterial growth by binding in the nascent peptide exit tunnel of the ribosome after the release of the completed protein and trapping the release factors. By genome mining, we have identified 71 PrAMPs encoded in insect genomes as pre-pro-polyproteins. Ha

The goal of this work is to specify and investigate suitability of a number of selected permanent magnet synchronous machine (PMSM) topologies to be mounted directly on a low pressure shaft (LPS) of a geared turbofan engine. The starting point of the work is to explore the status of electrical machines for more electric engine in order to study different design aspects when identifying and defininThe goal of this work is to specify and investigate suitability of a number of selected permanent magnet synchronous machine (PMSM) topologies to be mounted directly on a low pressure shaft (LPS) of a geared turbofan engine. The starting point of the work is to explore the status of electrical machines for more electric engine in order to study different design aspects when identifying and definin

Background: Learning is a lifelong process and the workplace is an essential arena for professional learning. Workplace learning is particularly relevant for midwives as essential knowledge and skills are gained through clinical work. A clinical practice known as ‘Collegial Midwifery Assistance’ (CMA), which involves two midwives being present during the active second stage of labour, was found to

Two electrotechnologies: pulsed electric fields (PEF) and moderate electric field (MEF) in combination with vacuum impregnation of glycerol as cryoprotectant were used to increase the freezing tolerance of rocket leaves. Rocket leaves were treated with PEF using a nominal field strength of 1200 V/cm or MEF at different combinations of voltage and frequency. Leaves were then immersed in a glycerol

BACKGROUND: Cut-points to define slow walking speed have largely been derived from expert opinion. METHODS: Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% me

A novel S-scheme photocatalytic heterojunction composite nanomaterial is developed by integrating zero-dimensional WO3 quantum dots (WQDs) on two-dimensional ultrathin CdIn2S4 (CIS) nanosheets with the aim of fostering carrier separation, enhancing the performance of carrier interface transport, minimizing carrier distance transport, and achieving effective photocatalytic CO2 reduction. The compos

This paper describes an algorithm for reconstructing and identifying a highly collimated hadronically decaying τ-lepton pair with low transverse momentum. When two τ-leptons are highly collimated, their visible decay products might overlap, degrading the reconstruction performance for each of the τ-leptons. A dedicated treatment attempting to tag the τ-lepton pair as a single object is required. T