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Background: CSF concentration of neurogranin has been suggested as a biomarker for synapse dysfunction. Objectives: To investigate CSF neurogranin in parkinsonian disorders compared to controls and Alzheimer's disease and the possible correlations between neurogranin and cognitive and motor impairment. Methods: We included 157 patients with PD, 29 with PD with dementia, 11 with dementia with Lewy

Syftet med att granska den globala fördelningen och temporära förändringar av 7Be, 210Pb och 210Po i ytluften är att analysera och modellera de data som avslöjades under de svenska polarexpeditionerna med andra publicerade resultat.Förhållandet mellan luftkoncentrationer och avsättningar av 7Be, 210Pb och 210Po modellerades till tidsperioden för datainsamling, latitud, longitud och höjd över havet

Increasing loading of terrestrially derived dissolved organic matter tends to enhance bacterioplankton respiration (BR) in boreal estuaries, but knowledge on the mechanisms behind this effect is not complete. We determined the stable isotopic signature of the reactive estuarine dissolved organic carbon (DOC) in the Öre estuary (Baltic Sea) by using the Keeling plot method. The δ13C ratio of the es

Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, but the nature of the suggestive comorbidity is still unknown. We used a novel genetic pleiotropy-informed conditional False Discovery Rate (FDR) method to identify single nucl

Wildland-urban interface (WUI) fire incidents are likely to become more severe and will affect more and more people. Given their scale and complexity, WUI incidents require a multidomain approach to assess their impact and the effectiveness of any mitigation efforts. The authors recently produced a specification for a simulation framework that quantifies evacuation performance during WUI incidents

Natural hybridization occurs commonly in plants and blurs their interspecific delimitation. It is unclear whether spontaneous hybridization occurs in natural populations of Primula in China. In this study we examined natural hybridization between P. secundiflora and P. poissonii based on morphological and molecular analyses of individuals with intermediate morphology. Most morphological characters

The effects of insulin (10-1000 microU ml-1) on chylomicron remnant uptake and degradation were studied in hepatocyte monolayer cultures. Both uptake and degradation were stimulated by insulin. The degree of stimulation was influenced by cell density, being most pronounced in sparse cultures. The uptake was stimulated in a dose-dependent fashion and was noticed already at a physiological insulin l

The stereoselective reduction of ketones catalysed by alcohol dehydrogenase from Thermoanaerobium brockii was studied in different reaction media, hexane at controlled water activities, hexane with 2.5% water (biphasic) and pure water. The reactions were studied in the temperature range from -1 to 50°C. Increasing the water activity from 0.53 to 0.97 increased the reaction rate 16-fold. The rate w

Project Report LUDICH Layout 17 Jun LL ENGLISH Project Report 1 LUDICH: Lund University Digital Interactive Concert Hall Thematic Collaboration Initiative Final report Date 2025-12-31 Faculty of Fine and Performing Arts, office Jesper Larsson, Expert and project leader Postal address Box 117, 221 00 Lund Visiting address Arkeologen, Sandgatan 1, Lund Phone 046-222 00 00 Email projektkontoret@rekto

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/2026-06/Project%20Report%20LUDICH%20English.pdf - 2026-07-22

Plate tectonics is a unique feature of Earth, but its proposed time of initiation is still controversial, with published estimates ranging from ca. 4.2 to 0.7 Ga. Paleomagnetic data can provide a robust argument for one essential aspect of plate tectonics: large-scale relative lateral motions of distinct, rigid crustal blocks. Previously, the oldest relative horizontal motion between two or more b

Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabet

Att diagnostisera en hörselnedsättning och inleda habilitering så tidigt som möjligt på små barn har visat sig vara av stor betydelse. Genom åren har flera olika diagnostiska metoder utvecklats får att kunna utföra hörselmätningar på små barn. I Linköping utarbetades 1996 ett datorstött mätsystem för barnaudiometri. Systemet är en variant av tittlådeaudiometri, Visual Reinforcement Audiometry (VRA

Osteonecrosis (ON) is a common complication of glucocorticoid-based Hodgkin lymphoma (HL) treatment, but the natural evolution and prognosis of ON lesions remain poorly understood. We describe the radiological evolution of ON lesions identified in a Nordic population-based cohort of paediatric HL patients. Magnetic resonance images of suspected ON lesions were centrally reviewed to confirm ON diag

Considering the ever increasing financial damages of floods and the need to manage the surface water, the use of new and more sufficient methods seems to be necessary. Therefore, the present study aims to investigate capability of the Gamma, Beta, Chi-square, and Weibull probability distribution functions (PDFs) for flood hydrograph derivation. The present study was conducted in the Bar watershed,