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IMPORTANCE In age-related macular degeneration (AMD), rare variants in the complement system have been described, but their functional consequences remain largely unexplored. OBJECTIVES To identify new rare variants in complement genes and determine the functional effect of identified variants on complement levels and complement regulation in serum samples from carriers and noncarriers. DESIGN, SE
The relationships between abdominal and pelvic fat compartments and glucose and lipid metabolism were investigated in early postmenopausal women. Fifty-five healthy, postmenopausal women aged 52-53 yr participated in the study. Fat distribution (intra-abdominal and sc abdominal fat, and intrapelvic and sc pelvic fat) was estimated by computed tomography. Insulin sensitivity was assessed by euglyce
This case study investigates the development of subject-specific literacy in Physical Education and Health (PEH) for second language (L2) learners within a Swedish secondary school context. Integrating Systemic Functional Linguistics (SFL) and Legitimation Code Theory (LCT), the study introduces the concept of embodied cohesion to analyze how meaning is constructed across verbal, graphic, and phys
Experimental data on analog performance of gate-all-around III-V vertical Tunnel Field-Effect Transistors (TFETs) and circuits are presented. The individual device shows a minimal subthreshold swing of 44 mV/dec and transconductance efficiency of 50 V−1 for current range of 9 nA/μm to 100 nA/μm and at a drain voltage of 100 mV. This TFET demonstrates translinearity between transconductance and dra
Background: Hypertension is the leading risk factor for cerebral small vessel disease. We aimed to determine whether antihypertensive drug classes differentially affect microvascular function in people with small vessel disease. Methods: We did a multicentre, open-label, randomised crossover trial with blinded endpoint assessment at five specialist centres in Europe. We included participants aged
Background: Various factors modulate circulating testosterone in men, affecting interpretation of testosterone measurements. Purpose: To clarify factors associated with variations in sex hormone concentrations. Data Sources: Systematic literature searches (to July 2019). Study Selection: Prospective cohort studies of community-dwelling men with total testosterone measured using mass spectrometry.
Order Picking in warehouses is often optimized with a method known as Order Batching, which means thatone vehicle can be assigned to pick a batch of several orders at a time. Although there exists a rich body ofresearch on Order Batching Problem (OBP) optimization, one area which demands more attention is that ofcomputational efficiency, especially for optimization scenarios where warehouses have
Although there are some epigenome-wide association studies (EWAS) of insulin resistance, most of them did not replicate their findings and are focused in populations of European ancestry limiting the generalizability. In EPIPREG (294 Europeans and 162 South Asians), we conducted an EWAS of insulin resistance in maternal peripheral blood leukocytes, with replication in Born in Bradford (n=879; 430
Order Picking in warehouses is often optimized using a method known as Order Batching, which means that one vehicle can be assigned to pick a batch of several orders at a time. There exists a rich body of research on Order Batching Problem (OBP) optimization, but one area which demands more attention is computational efficiency, especially for optimization scenarios where warehouses have unconvent
Metabolically engineered baker’s yeast can be used to produce chiral amines through whole-cell bioconversion of prochiral ketones. This study investigates the modulation of the alanine-pyruvate metabolic node to enhance reductive amination, using the stereoselective conversion of benzylacetone to (S)-1-methyl-3-phenylpropylamine (MPPA) as a model reaction. Chromosomal integration of multiple copie
Complex recombinant biomaterials that merge the self-assembling properties of different (poly)peptides provide a powerful tool for the achievement of specific structures, such as hydrogel networks, by tuning the thermodynamics and kinetics of the system through a tailored molecular design. In this work, elastin-like (EL) and silk-like (SL) polypeptides are combined to obtain a silk-elastin-like re
Cerebrospinal fluid (CSF) α-synuclein (α-syn) seed amplification assays (SAAs) can detect Lewy body pathology (LBP) with high accuracy but are invasive and costly. To address these challenges, this study evaluated a two-step workflow combining prescreening via smell-function testing with confirmatory CSF α-syn SAA testing only in individuals with reduced smell, for predicting postmortem LBP status
Coarctation of the aorta is a congenital heart anomalyinvolving constriction of an aortic segment, associated with wall thickening of media and the formationof overlapping infolding of neointimal tissue. For thefirst time it was described by Morgagni in 1760. Thispathology represents 5% -7% of all congenital heartdiseases, with an incidence of approximately 3 casesto 10 000 neonates1. The typical
"The Academy of St Martin in the Fields are joined by Håkan Hardenberger who will perform a programme celebrating his history with the orchestra, including Haydn’s Trumpet Concerto and a selection from his album Both Sides Now, both recorded with ASMF."These pieces were performed:Georg Philipp Telemann: Konzert für drei Trompeten, zwei Oboen, Pauken, Streicher und B.c. D-dur TWV 54:D3Wolfgang Amad
Background: Global climate change is already increasing the average temperature and direct heat exposure in many places around the world. Objectives: To assess the potential impact on occupational health and work capacity for people exposed at work to increasing heat due to climate change. Design: A brief review of basic thermal physiology mechanisms, occupational heat exposure guidelines and heat
Microsoft Word - Development Research Day 2017.docx Development Research Day 2017 SEMINARIUM The Development Research Day is an annual event at Lund University bringing together all fields working on development to share and discuss their research with each other, students and the general public. This year’s theme is ”Long-term trends in global inequality and development”, and the day is organized
https://www.svet.lu.se/en/sites/svet.lu.se.en/files/development_research_day_2017.pdf - 2026-07-22
1 Programme for Research Symposium 22/12 2018 Developments in epidemiology and biomarker research A life-course perspective Time: Thursday March 21st 2019, start 10:00, end Friday March 22nd 2019 at 12:00 p.m. Place: “Lilla Aulan” Lecture Hall, Jan Waldenströms gata 2-5, Skåne University Hospital (SUS), Malmö, Sweden Organisers: The Strategic Research Area (SRA) Epidemiology for Health (EpiHealth)
SYFTE Avfallshandbok Dokumentets namn Gäller för Dnr Sida Avfallshandbok Lunds universitet V 2016-370 2 (67) Utarbetad av Godkänd av Utgåva Datum Miljösamordare Miljöchef 1 2016-02-10 INNEHÅLL 1. Inledning............................................................................................................................ 4 1.1 Om denna avfallshandbok ........................................
https://www.geologi.lu.se/sites/geologi.lu.se/files/avfallshandbok_-lu_ac.pdf - 2026-07-22
Proposal Guidelines 2018 Call 2 EIT Climate-KIC 1 PROPOSAL GUIDELINES EIT BUSINESS PLAN 2018 Call 2 Deadline for Application: 2nd March 2018 Covering Earlier-Stage Innovation: Pathfinder and Partner Accelerator Later-Stage Innovation: Demonstrator, Scaler, and Urban Challenges Other Innovation: Climate Innovation Ecosystems Education: Online Education and Professional Education Publication Date: 1
https://www.climate-kic.lu.se/sites/climate-kic.lu.se/files/proposal_guidelines_2018_call_2_v1-12.pdf - 2026-07-22
