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Molecular mapping of epitopes for interaction of HIV-1 as well as natural ligands with the chemokine receptors, CCR5 and CXCR4.

OBJECTIVE: Mapping coreceptor epitopes used by the prototypic R5 and X4 strains, HIV-1BaL and HIV-1IIIB, in comparison with epitopes involved in the activation and signaling induced by the natural ligands, RANTES and SDF-1beta. DESIGN: Receptor hybrids between CCR5 and CXCR4 were constructed. METHODS: Using single-overlap and extension PCR, increasing portions of CCR5 were replaced with correspond

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The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this purpose, an approach was attempted which was previously successfully applied in rabbits, aiming for induction of post-streptococcal glomerulonephritis (PSGN). To induce the nephropathy, we used two Streptococcus pyogenes strains of M4 and M60 serotypes which showed differential IgA-binding capacity me

GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65

GAD65 autoantibodies (GAD65Ab) are highly prevalent in type 1 diabetes, but their functional role in the pathogenesis of the disease and their relationship to T-cell reactivity to GAD65 is still unclear. We tested the hypothesis that GAD65Ab modulate presentation of GAD65 to T-cells. T-cell hybridoma T33.1, which recognizes the GAD65 274-286 epitope in the context of HLA-DRB1*0401, was incubated w

Experiments and Large Eddy Simulation of Supersonic Combustion in the Small-Scale Flight Experiment

Supersonic combustion is a critical area of research for advancing high-speed flight technologies, particularly for the development of scramjet engines for hypersonic vehicles. This study employs Finite Rate Chemistry (FRC) Large Eddy Simulation (LES) together with different experimental techniques to study the supersonic flow and thermochemical processes in the Small Scale Flight Experiment (SSFE

Serum Complement Activation by C4BP-IgM Fusion Protein Can Restore Susceptibility to Antibiotics in Neisseria gonorrhoeae

Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotics currently in clinical use have been rendered ineffective due to the rapid spread of antimicrobial resistance among gonococci. The developmental pipe

Production and Functional Characterization of Der p 1-Specific Human Recombinant IgE

Ny forskning bidrar till ökad förståelse av allergiska reaktioner Allergi har ökat dramatiskt under de senaste åren. Det är därför högst väsentligt att få ökad kunskap om hur beståndsdelarna i immunförsvaret hos allergiska personer samspelar. Förekomsten av allergi har kommit att öka dramatiskt under de senaste åren och har blivit ett betydande problem för folkhälsan. Allergi drabbar en så stor dThe prevalence of allergic disease is continuing to increase worldwide, and it has even become a major concern in public health. Allergic reactions are developed to otherwise harmless substances and may be both life-threatening as well as discomforting for patients in their daily life. Therefore, a more detailed knowledge about how antibodies interact with allergens and effector cells in allergic

IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.

Recent work from several laboratories has demonstrated that proteolytic mechanisms significantly contribute to the molecular interplay between Streptococcus pyogenes, an important human pathogen, and its host. Here we describe the identification, purification and characterization of a novel extracellular cysteine proteinase produced by S.pyogenes. This enzyme, designated IdeS for Immunoglobulin G-

Verksamhetsberattelse 2017 for eds nordic user group

Bilaga 1 Verksamhetsberättelse 2017 för EDS Nordic User Group Vid EDS Nordic User Groups årsmöte 2017-03-22 i Luleå valdes följande styrelsemedlemmar: ordförande Cilla Öhnfeldt, Stockholms universitet (omval), Per Falk, Högskolan i Gävle (nyval), Ann- Christin Persson, Lunds universitet (nyval), Tove Andersson, Region Skåne (nyval), Mikael Arvidsson, Karlstads universitet (omval) och Eva Sejmyr, L

https://www.ub.lu.se/sites/ub.lu.se/files/verksamhetsberattelse_2017_for_eds_nordic_user_group.pdf - 2026-05-06

Jullovsöppet med Atomresan

30 december 2025 12:00 till 17:00 | Barn- och ungdomsevenemang, Övrigt På Vattenhallen Science Center finns det mycket att upptäcka. Välkommen på ett jullovsbesök! DAGENS SHOWERKl 13.00: AtomresanMed glödheta och superkalla experiment reser vi från stenåldern till modern tid med hjälp av människans nyfikenhet och finurlighet.   Kl 15.00: Luft & Vattenshow Häng med när våra studenter showar om luft

https://www.lu.se/evenemang/jullovsoppet-med-atomresan - 2026-05-06

Tracing Smartphone-Enabled Customer Journeys : A Socio-Material Approach

This doctoral thesis delves into the transformation of the customer journey—that is, the direct and indirect interactions between a customer and retailer over time—in the smartphone era. Using a socio-material perspective, it goes beyond current visions of the customer journey, which often focus on emotions and experiences, and instead explores how agency is distributed across elements that includThis doctoral thesis delves into the transformation of the customer journey—that is, the direct and indirect interactions between a customer and retailer over time—in the smartphone era. Using a socio-material perspective, it goes beyond current visions of the customer journey, which often focus on emotions and experiences, and instead explores how agency is distributed across elements that includ

Litteraturlista Den Mångdimensionella Musikläraren Ht22T

Lägg till titel Sida 1 av 3 Ämneslärarutbildning i musik Datum 2022-06-20 Litteraturlista Den Mångdimensionella Musikläraren ht 2022 Beghetto, Ronald. A. (2021). Creativity in K-12-schools. In Sternberg, R. J. & Kaufman, J. C. (Eds.). Creativity: An introduction. Cambridge University Press. (s. 224-236) [13 sidor, se pdf i Canvas] Björkman, Lotta. (2019) Om att förstå vad vi inte förstår för

https://www.mhm.lu.se/sites/mhm.lu.se/files/2022-06/Litteraturlista%20Den%20Ma%CC%8Angdimensionella%20Musikla%CC%88raren%20ht22T.pdf - 2026-05-06

Svenska, språklig inriktning 1–40 poäng

Svenska, språklig inriktning 1–40 poäng Vårterminen 2016 Litteraturlista för SVEN01, Grammatisk och fonologisk utveckling i ett andraspråk, avancerad nivå, 7,5 högskolepoäng Fastställd av sektion 1 vid Språk- och litteraturcentrum den 2 december 2015. Obligatorisk litteratur Corder, Pit. 1967. The significance of learner errors. International Review of Applied Linguistics, 5. 161–170. Ekerot, Lars

https://www.sol.lu.se/media/utbildning/dokument/kurser/SVEN01/20161/SVEN01_KLAR.pdf - 2026-05-04

Jullovsöppet med Luft- och vattenshow

4 januari 2026 12:00 till 17:00 | Barn- och ungdomsevenemang, Övrigt På Vattenhallen Science Center finns det mycket att upptäcka. Välkommen på ett jullovsbesök! DAGENS SHOWERKl 13.00 och 15.00: Luft & Vattenshow Häng med när våra studenter showar om luft och vatten! Vad händer med en marshmallow i vakuum eller med en ballong i flytande kväve? Och hur känns ett moln? Det och mycket mer får du uppl

https://www.lu.se/evenemang/jullovsoppet-med-luft-och-vattenshow - 2026-05-06