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Challenges of implementing decision support systems: Joining the views of consultant and customer
In today's business environment, organizations rely on information systems to store and process the information constantly gathered. These systems are used to support the everyday needs of the organization. It is apparent that many of these systems has limited or no analytical capabilities, can the introduction of a decision support system could enable practitioners to benefit from this can th
Toward clinical use of the IgG specific enzymes IdeS and EndoS against antibody-mediated diseases
IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.
EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca
Prevention and Management of Bleeding Episodes in Children with Hemophilia
Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat
Induction of platelet thrombi by bacteria and antibodies.
We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai
Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5
Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami
Countercurrent distribution of lymphocytes from human peripheral blood in an aqueous two-phase system. : II. Separation into subsets of lymphocytes with distinctive functions
Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti
Investigation of bubble departure radius in subcooled pool boiling under microgravity condition
Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins
Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T
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OPEN EVENT: LU @ Humanities Lab!
1997cv cesilia sterner
contact@ceciliasterner.com www.ceciliasterner.com +46-707-516207 2001 Publikation #14, Rollon, Malmö 2000 Gallery C. Hjärne, Helsingborg 2000 Shoot- Moving Pictures by Artists, biograf Spegeln, Malmö 2000 Aura, Krognoshuset i Lund 1999 Rollon, www.rollon.net 1999 South City Drawings, The Pineapple 1999 Rollon, Panora, Malmö 1999 Whiteout Greyout Blackout, Barbacka konsthall, Kristianstad 1997 Mike
https://www.khm.lu.se/sites/khm.lu.se/files/1997cv_cesilia_sterner.pdf - 2026-05-04
