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Reduced breast cancer mortality after 20+ years of follow-up in the Swedish randomized controlled mammography trials in Malmö, Stockholm, and Göteborg

Objective: To analyze the age- and trial-specific effects of the breast cancer screening trials with mammography in Malmö, Stockholm, and Göteborg. Methods: The original trial files were linked to the Swedish Cancer and Cause of Death Registers to obtain date of breast cancer diagnosis and date and cause of death. Relative risks and 95% confidence intervals were calculated using the evaluation mod

Downscaling and modelling of an ion-exchange chromatography column for purifying glucose solutions

Skalning och modellering av en kromatografikolonn för rening av sockerlösningar. För att uppnå klimatmålen behöver fossila råvaror inom kemiindustrin bytas ut mot förnybara råvaror. Socker är en råvara med stor potential inom industrin, men är ofta förorenat med salter. Därför utforskas rening av sockerlösningar här. För att använda socker som förnybar råvara för kemiindustri behöver sockret oftaTo utilize sugars as a feedstock for renewable industries, the feedstock often needs to be very pure. This is due to ionic species contaminating the sugar feedstock being potent catalyst poisons in many cases. To remove ionic species from the sugar feedstock, it is dissolved and purified using packed ion-exchange columns. In this report, a lab-scale setup of a large scale ion-exchange setup was co

The impact of reproductive factors on breast cancer risk - The feasibility of using Swedish population-based registers to account for the effect of confounding in cohort studies

Objective: The aim of this study was to analyze the impact of reproductive factors on breast cancer risk among Swedish women by using nationwide population registers. Methods: A cohort including all Swedish women born between 1920 and 1959 was followed up to 1997 by record linkage to different population-based registers. More than 4 million children were linked to the women in the cohort and 60,32

Institutional trust and alcohol consumption in Sweden: The Swedish National Public Health Survey 2006

Background: Trust as a measure of social capital has been documented to be associated with health. Mediating factors for this association are not well investigated. Harmful alcohol consumption is believed to be one of the mediating factors. We hypothesized that low social capital defined as low institutional trust is associated with harmful alcohol consumption. Methods: Data from the 2006 Swedish

Low Postnatal Serum IGF-I levels is Associated with Bronchopulmonary Dysplasia (BPD).

Aim: To characterize postnatal changes in serum IGF-I in relation to development of bronchopulmonary dysplasia (BPD) in very preterm infants. Methods: Longitudinal study of 108 infants with mean (SD) gestational age 27.2 (2.2) weeks. Weekly serum samples of IGF-I were analyzed from birth until postmenstrual age 36 weeks. Multivariate models were developed to identify independent predictors of

Recreational football training decreases risk factors for bone fractures in untrained premenopausal women

The present intervention was designed to investigate whether a 14-week period of regular recreational association football (F) or endurance running (R) has an effect on the risk of falls and bone fractures due to gains in muscle function and volumetric bone mineral density (vBMD). Fifty healthy untrained Danish premenopausal women were randomized into two training groups (F and R) that trained 1.8

Fermentation performance and intracellular metabolite patterns in laboratory and industrial xylose-fermenting Saccharomyces cerevisiae.

Heterologous genes for xylose utilization were introduced into an industrial Saccharomyces cerevisiae, strain A, with the aim of producing fuel ethanol from lignocellulosic feedstocks. Two transformants, A4 and A6, were evaluated by comparing the performance in 4-l anaerobic batch cultivations to both the parent strain and a laboratory xylose-utilizing strain: S. cerevisiae TMB 3001. During growth

The complexity of daily occupations in multiple sclerosis.

The aims of this study were to describe which self-care, productivity, and leisure occupations individuals with multiple sclerosis (MS) perceive as difficult to perform on admission to rehabilitation and the individuals' own perception of the importance of, performance of, and satisfaction with these occupations. Whether the reported self-care, productivity, and leisure occupations were related to

Intima samhällsvisioner : Sporten mellan minimalism och gigantism

Ambitions and ClarificationsThe book takes its point of departure in the "intimate visions of society" that are significant of contemporary social life. This concept refers to the tendency to apprehend good social relations as personal, close and warm, while bad relations correspondingly are perceived as impersonal, cold, distant and alienated. Exemplary categories, such as closeness, warmth, commAmbitions and ClarificationsThe book takes its point of departure in the "intimate visions of society" that are significant of contemporary social life. This concept refers to the tendency to apprehend good social relations as personal, close and warm, while bad relations correspondingly are perceived as impersonal, cold, distant and alienated. Exemplary categories, such as closeness, warmth, comm

Prevalence of G6PD deficiency and associated haematological parameters in children from Botswana

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is commonly seen in malaria endemic areas as it is known to confer a selective advantage against malaria. Recently, we reported a high proportion of asymptomatic reservoir of Plasmodium vivax in Botswana, that calls for intervention with primaquine to achieve radical cure of vivax malaria. Considering that individuals with this enzyme deficiency

3D-macroporous chitosan-based scaffolds with in situ formed Pd and Pt nanoparticles for nitrophenol reduction

3D-macroporous chitosan-based scaffolds (cryogels) were produced via growth of metal-polymer coordinated complexes and electrostatic interactions between oppositely charged groups of chitosan and metal ions under subzero temperatures. A mechanism of reduction of noble metal complexes inside the cryogel walls by glutaraldehyde is proposed, which produces discrete and dispersed noble metal nanoparti

University and medical education and the risk of cancer in Sweden

Socio-economic gradients are known to exist in cancer but we want to focus on the university-educated population and specifically on physicians to find out whether their special educational background on cancer causation helps them to avoid cancers. The analysis was based on the latest update of the Swedish Family-Cancer Database, in which the educational level was obtained from the national censu

A review of studies assessing ecosystem services provided by urban green and blue infrastructure

Urban green and blue infrastructure (GBI) and associated ecosystem services (ES) are increasingly recognized for their potential to address urban sustainability challenges. This has resulted in an increase in studies quantifying ES in cities. In this review, we analysed 850 peer-reviewed publications to characterize urban ES assessment in terms of geographical location, urban GBI type and methodol

Contact dermatitis from glucose sensors in Spain : A multicentric approach

Background: Allergic contact dermatitis from glucose sensors may interfere with their ongoing application. Objective: To evaluate a series of Spanish patients with contact dermatitis to glucose sensors regarding former sources of contact allergens, patch test results, and outcomes from the ongoing use of the device. Methods: A series of patients with contact dermatitis from glucose sensors was inv

Sociodemographic factors and uncomplicated pyelonephritis in women aged 15-50 years : a nationwide Swedish cohort register study (1997-2018)

Objective: To study the relationship between sociodemographic factors and pyelonephritis. Methods: A nationwide open cohort study consisting of 2,052,873 women (76.2% Swedish-born) aged 15-50 years was conducted (1997-2018). The outcome was the first event of acute uncomplicated pyelonephritis diagnosed in primary healthcare settings in relation to the sociodemographic factors. Cox regression mode

Knowledge and Awareness of Algerian Students about Cervical Cancer, HPV and HPV Vaccines : A Cross-Sectional Study

Cervical cancer is one of the most recurrent and dangerous female cancers in Algeria and worldwide. It is mainly caused by human papillomaviruses (HPV), which can induce other cancers as well. Although it can be fatal, cervical cancer is one of the most preventable and manageable cancers. While HPV vaccination is the key weapon to win the battle against this pathology, it is still not approved in

Disappointment and drop-out rate after being allocated to control group in a smoking cessation trial

BackgroundIf a patient agrees to take part in a randomised trial it is reasonable to presume that the patient would prefer to be allocated into the intervention. This study's aim was to investigate how patients react after they have been randomised into control group.MethodsNested study within two randomised trials. Telephone interviews with a structured questionnaire. The participants were invite

Cone-beam computed tomography, a new low-dose three-dimensional imaging technique for assessment of bone erosions in rheumatoid arthritis : reliability assessment and comparison with conventional radiography – a BARFOT study

Objectives: To determine the intra- and inter-observer agreement of erosions detected and scored with cone-beam computed tomography (CBCT) of bones in the hands and feet, and to compare CBCT with conventional radiography (CR) for assessment of bone erosions in patients with long-standing rheumatoid arthritis (RA). Method: Thirty patients with long-standing RA from the Better Anti-Rheumatic Pharmac

Oxygen Exposure and Tolerance Shapes the Cell Wall-Associated Lipids of the Skin Commensal Cutibacterium acnes

Cutibacterium acnes is one of the most abundant bacteria on the skin. Being exposed to oxygen and oxic stress, the secretion of the bacterial antioxidant protein RoxP ensures an endogenous antioxidant system for the preservation of skin health. To investigate the impact of the antioxidant RoxP on oxidation of the bacteria, wildtype and an isogenic roxp mutant were cultured in anaerobic and oxic co