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Design and measurement of a CT delta-sigma ADC with switched-capacitor switched-resistor feedback

The performance of traditional continuous-time (CT) delta-sigma analog-to-digital converters (ADCs) is limited by their large sensitivity to feedback pulse-width variations caused by clock jitter in their feedback digital-to-analog converters (DACs). To mitigate that effect, we propose a modified switched-capacitor (SC) feedback DAC technique, with a variable switched series resistor (SR). The arc

Inhibitory properties of cystatin F and its localization in U937 promonocyte cells

Cystatin F is a recently discovered type II cystatin expressed almost exclusively in immune cells. It is present intracellularly in lysosome-like vesicles, which suggests a potential role in regulating papain-like cathepsins involved in antigen presentation. Therefore, interactions of cystatin F with several of its potential targets, cathepsins F, K, V, S, H, X and C, were studied in vitro. Cystat

Airway effects of salmeterol in healthy individuals

The long-acting beta 2-agonist salmeterol has been shown in several in vitro studies to produce non-beta-mediated relaxant effects. The aim of the present study was to investigate whether these effects have any relevance in humans in vivo. Thirteen healthy individuals were studied in a randomized, double-blind, cross-over study on five separate days. The subjects were pre-treated orally with eithe

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Abstract in Norwegian Bakgrunn. Fallulykker er et viktig helseproblem hos eldre. Både balansetesting og registrering av egenrapportert funksjon kan være måter å forutse fremtidige ulykker på. Materiale og metode. I en kohortstudie ble egenrapportert gangfunksjon kartlagt hos 307 tilfeldig utvalgte hjemmeboende kvinner 75 år og eldre. Kvinnene gjennomgikk også testing av balanse og gangfunksjon, oBACKGROUND: Falls represent an important health problem among the elderly. Balance testing as well as registration of self-reported balance problems may be appropriate in order to predict the risk of future falls. MATERIALS AND METHODS: Self-reported walking was assessed in 307 randomly selected women 75 years or older living at home. The women underwent testing of gait and balance and were follow

Long term anti-tumour necrosis factor alpha monotherapy in rheumatoid arthritis: effect on radiological course and prognostic value of markers of cartilage turnover and endothelial activation.

Objectives: To investigate the effect of prolonged neutralisation of tumour necrosis factor alpha (TNFalpha) on the radiological course in rheumatoid arthritis (RA). To assess whether the radiological course can be predicted by clinical variables or biological markers of cartilage and synovium turnover and of endothelial activation. Patients and methods: Forty seven patients with active RA enrolle

Intrinsic femtosecond charge generation dynamics in single crystal CH3NH3PbI3

Hybrid metal-organic perovskite solar cells have astounded the solar cell community with their rapid rise in efficiency while maintaining low-cost fabrication. The intrinsic material photophysics related to the generation of free charges, their dynamics and efficiency, however, remains to be understood. As fabrication techniques improve, larger crystal grain sizes have been shown to be a critical

Heterogeneous nuclear ribonucleoprotein C proteins interact with the human papillomavirus type 16 (HPV16) early 3'-untranslated region and alleviate suppression of HPV16 late L1 mRNA splicing.

In order to identify cellular factors that regulate human papillomavirus type 16 (HPV16) gene expression, cervical cancer cells permissive for HPV16 late gene expression were identified and characterized. These cells either contained a novel spliced variant of the L1 mRNAs that bypassed the suppressed HPV16 late, 5'-splice site SD3632, produced elevated levels of RNA-binding proteins SRSF1 (ASF/SF

VIP potentiates cholinergic effects on the mucociliary system in the maxillary sinus

The neuropeptide vasoactive intestinal polypeptide (VIP), which is found in a population of cholinergic parasympathetic neurons in the airways, has no effects per se on mucociliary activity. In order to test the hypothesis that VIP may modulate cholinergic regulation of the mucociliary system, VIP was infused intraarterially (8.4 pmol/kg/min), and the response to challenges with methacholine in th

Quality of life and toxicity in breast cancer patients using adjuvant TAC (docetaxel, doxorubicin, cyclophosphamide), in comparison with FAC (doxorubicin, cyclophosphamide, 5-fluorouracil).

Abstract in UndeterminedThe aim of this study was to compare two regimens of chemotherapy in patients with breast cancer, including FAC (doxorubicin, cyclophosphamide, and 5-fluorouracil) and TAC (docetaxel, doxorubicin and cyclophosphamide); and analyze the toxicity of these treatments and observe patient's health-related quality of life.Health-related quality of life was assessed for up to 4 mon

Utbildningssegregation och självsortering : Om gymnasieval, genus och lokala praktiker

Popular Abstract in Swedish Denna avhandling utforskar och analyserar segregation och självsortering i utbildning. Den syftar till att diskutera hur detta relateras till genus, individualisering och unga mäns och kvinnors positioneringar i lokala praktiker, genom val av gymnasieutbildning. Den fokuserar hur unga män och kvinnor hanterar och anpssar sig till det förändrade senmoderna samhället. AvThis thesis explores and analyzes segregation and self-sorting in education. It aims at discussing how this relates to gender, individualization and young men and women's positionings in local practices, through choices of upper secondary school education. It focuses on how young men and women cope with and adapt to the changing society in late modernity. The thesis is based on three empirical st

Comparing University-Ownership Technology Transfer Systems With University-Inventor Technology Transfer Systems In Scandinavian Universities – A Question Of Focusing On Licensing Or Spin-Off Business Models?

Universities have become important components of the national innovation systems in innovation driven economies. To strengthen the university related flow of mainly technological knowledge into commercialized products many European countries have followed the American example and changed from an inventor-ownership system to a university-owned system (Genua & Rossi, 2011). Today most European c

An automatic method for quantification of myocardium at risk from myocardial perfusion SPECT in patients with acute coronary occlusion.

BACKGROUND: In order to determine myocardial salvage, accurate quantification of myocardium at risk (MaR) is necessary. We present a validated novel automatic segmentation algorithm for quantification of MaR by myocardial perfusion SPECT (MPS) in patients with acute coronary occlusion. METHODS AND RESULTS: Twenty-nine patients with coronary occlusion were injected with a perfusion tracer before re

Development and Implementation of Cardiac Event Detectors in Digital CMOS

This doctoral dissertation presents the development and digital hardware realization of cardiac event detectors. Implantable medical appliances, as the cardiac pacemaker, have progressed from a life sustaining device to a device that considerably improves life quality for all ages. The number of electronic devices and household appliances in everyday live has an ongoing exponential growth. The

Calculation of geomagnetically induced currents in the 400 kV power grid in southern Sweden

Sweden has experienced many geomagnetically induced current (GIC) events in the past, which is obviously due to the high-latitude location of the country. The largest GIC, almost 300 A, was measured in southern Sweden in the earthing lead of a 400 kV transformer neutral during the magnetic storm on 6 April 2000. On 30 October 2003, the city of Malmo at the southern coast suffered from a power blac

Space weather events in July 1982 and October 2003 and the effects of geomagnetically induced currents on Swedish technical systems

In this paper, we analyse in detail two famous space weather events; a railway problem on 13-14 July 1982 and a power blackout on 30 October 2003. Both occurred in Sweden during very intensive space weather storms and each of them a few years after the sunspot maximum. This paper provides a description of the conditions on the Sun and in the solar wind leading to the two GIC events on the ground.

Theoretical study of the unusual potential energy curve of the A (1)Sigma(+) state of AgH

The A (1)Sigma(+) potential energy curve of AgH is studied by means of the second-order multistate multireference perturbation theory including the spin-orbit and relativistic effects. The anomalous behavior of the vibrational energy levels observed in experiment is reproduced well by theory. An analysis of the A (1)Sigma(+) wave function shows that at the internuclear distance of 4-6 Angstrom, a

What is ideal genetic counselling? A survey of current international guidelines

The objective of this article is to review guidelines that address counselling in the context of genetic testing in order to summarise what aspects of counselling they consider most important, and to examine how they construct the ideal of genetic counselling. Guidelines were collected by examining the websites of different international professional, political, ethical and patient organisations,

Correlates of Nine-Month Retention following Interim Buprenorphine-Naloxone Treatment in Opioid Dependence: A Pilot Study.

Interim medication-only treatment has been suggested for the initiation of opioid maintenance treatment (OMT) in opioid-dependent subjects, but this rarely has been studied using buprenorphine instead of methadone. Following a pilot trial assessing interim buprenorphine-naloxone treatment in order to facilitate transfer into OMT, we here aimed to study retention, and potential correlates of retent

Bleeding peptic ulcer - time trends in incidence, treatment and mortality in Sweden.

Abstract Background: The incidence of peptic ulcer disease was expected to decrease following the introduction of acid inhibitors and H. pylori eradication. Aim: This study analyses possible changes in the incidence of bleeding peptic ulcer, treatment and mortality over time. Methods: Residents of Malmö hospitalised for bleeding gastric or duodenal ulcer disease1987-2004 were identified in hospita