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Performance of five cardiotocography classification templates in labor : a cohort study

Objective: New guidelines for the interpretation of cardiotocography (CTG) have been presented by FIGO in 2015 (FIGO-15) and by NICE in 2017 (NICE-17) and 2022 (NICE-22) In Sweden, a previous template from 2009 (SWE-09) was replaced in 2017 (SWE-17). The objective of the study was to compare these five different templates for CTG classification regarding sensitivity, specificity, positive and nega

Plasma VEGF-D and sFLT-1 are potential biomarkers of hemodynamics and congestion in heart failure and following heart transplantation

BackgroundInflammation and tyrosine-kinases are known mediators in the pathobiology of cardiovascular disease. Plasma biomarkers reflecting these systems may provide a noninvasive complement reflecting hemodynamics, aiding in clinical decision-making. We therefore aimed to investigate the plasma levels of vascular and inflammatory proteins, and their associations with invasive hemodynamics in adva

"Äh sugardejting i sig det är ju alltså prostitution". En rättssociologisk studie om sugardejting

Sugar dating is a phenomenon in which peoples’ company and intimacy is traded for gifts and luxurious consumption. This study investigates what difficulties and possibilities exist for the regulation of sugar dating. In order to answer this question, the study also investigates how representatives of the Swedish police and the County Administrative Boards of Sweden(länsstyrelser) perceive the phen

Skuldsatt och utsatt. Inverkan av psykologiska mekanismer och samhälleliga instanser på psykisk ohälsa hos överskuldsatta i Sverige

Psykisk ohälsa är vanligt förekommande bland överskuldsatta individer. Föreliggande enkätstudie studerade psykologiska mekanismer som kan öka förståelsen för psykisk ohälsa hos överskuldsatta i Sverige. Deltagarna (n=647) rekryterades via Kronofogden, Yrkesföreningen för budgetrådgivare samt Insolvens – Riksförbundet för överskuldsatta. Skillnader undersöktes inom gruppen överskuldsatta mellan indThe present study examined psychological mechanisms in order to increase knowledge regarding mental illness amongst 647 over-indebted individuals in Sweden. Differences were explored between individuals with probable clinical depression and/or anxiety and individuals without probable clinical depression and/or anxiety considering objective measurements of the debt, financial strain, coping, contac

Moral Branding - The role of a moral brand in a context of organizational culture, identity & change

Purpose: To gain an understanding of how organizational culture and identity are seen as interrelated with a moral brand, by investigating a company that is going through an organizational change. In addition to this, we intend to explore what happens with a company’s moral brand, culture, and identity, when going through these kinds of changes. Research question: How are culture and identity rel

Big Data - konkurrensfördel idag, överlevnad imorgon

Att göra en studie om hur detaljhandelsföretag tar tillvara på och hanterar Big Data för att stärka sina kundrelationer samt hur de kan förbättras. Vi har utfört en kvalitativ fallstudie i form av djupintervjuer samt en egen undersökning. Djupintervjuerna har haft en semistrukturerad uppbyggnad. Den egna undersökningen har en komparativ karaktär där insamlingen av data gällande kunder, har jämförA study about how retail companies collect and manage Big Data in order to strengthen and develop their customer relationship. The study is one of qualitative character, which is built upon several in-depth interviews as well as a survey performed by the authors. The in-depth interviews are semi-structured. The survey is of comparative nature where the gathering of customer-driven-data is compar

Renommésnyltning och "smell-alikes" - det känneteckens- och marknadsrättsliga skyddet mot renommésnyltande parfymimitationer

Syftet med denna uppsats är att undersöka de för parfymtillverkare tillgängliga varumärkes- och marknadsrättsliga verktygen mot snålskjutsfenomenet ”smell-alikes”, dvs. efterbildningar av välkända märkesparfymer av lägre kvalitet som säljs för en bråkdel av originalpriset. I avsaknad av ett självklart, juridiskt varumärkesskydd för dofter lämnas producenterna att förlita sig på det varumärkesrätThe aim of this paper is to investigate the legal tools available for perfume producers in trademark and market law against the free-riding phenomenon “smell-alikes”, i.e. imitations of famous brand perfumes of lower quality sold at a fraction of the original price. In the absence of evident legal trademark protection for fragrances, manufacturers have to rely on the trademark protection granted

Intermittent PTH((1-34)) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures.

Intermittent Parathyroid Hormone (PTH)((1-34)) has an established place in osteoporosis treatment, but also shows promising results in models of bone repair. Previous studies have been dominated by closed fracture models, where union is certain. One of the major clinical needs for anabolic therapies is the treatment of open and high energy fractures at risk of non-union. In the present study we th

Severe Hemodilution - Clinical and Experimental Studies

Popular Abstract in Swedish Under det senaste decenniet har risker med och alternativ till allogent blod (blod från främmande givare) debatterats mycket pga. risken för smitta, allergiska reaktioner, samt starka indicier som talar för att blod från främmande givare kan påverka immunförsvaret hos mottagaren. Därför vill man gärna begränsa mängden tillfört givarblod under kirurgiska ingrepp på barn,In children, it is often desirable to minimize allogenic blood transfusion, and this thesis explores the physiology of an alternative method of managing perioperative blood loss: hemodilution with Ringer´s dextran. Methods Clinical studies: Arterial pressure, superior caval venous oxygen saturation (ScvO2) and blood lactate concentration (L) were studied during bone marrow harvesting (BMH) on 23

What Do You Like? Early Design Explorations of Sound and Haptic Preferences

This study is done within the framework of a project aimed at developing a wearable device (a bracelet) intended to support sensory motor rehabilitation of children with visual impairments. We present an exploratory study of aesthetic/hedonistic preferences for sounds and touch experiences among visually impaired children. The work is done in a participatory setting, and we have used mixed methods

A 30 GHz 90-nm CMOS Passive Subharmonic Mixer with 15 GHz Differential LO

A new passive subharmonic mixer topology is presented and compared to a previously published passive topology. The comparison is conducted using simulations at 30 GHz with a 90-nm CMOS design kit. The advantage of the new passive subharmonic mixer is that it only requires a differential local oscillator (LO) signal, compared to the previously published mixer that requires a quadrature LO signal. T

Does SISCOM contribute to favorable seizure outcome after epilepsy surgery?

Purpose: To assess the additional value of subtraction ictal single-photon emission computed tomography (SPECT) coregistered to MRI (SISCOM) for localization of the epileptogenic zone in patients with drug-resistant epilepsy scheduled for invasive video-EEG (VEEG) before epilepsy surgery by a descriptive study from clinical practice. Methods: Forty-nine consecutive epilepsy patients between Januar

Depressive symptoms, atherosclerotic burden and cerebral blood flow disturbances in a cohort of octogenarian men from a general population

Background: The aim of this study was to examine in elderly men a relationship between depressive symptoms, peripheral vascular disease and cerebral blood flow (CBF). Methods: Population-based cohort study started with an examination of 809 men at age 55, followed by the first (age 68ys) and second follow up (age 82ys). 128 survivors were examined at age 82 with Tc-99m-HMPAO-SPECT to estimate CBF,

Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer

Background: Podocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein and stem cell marker that has been associated with an aggressive tumour phenotype and adverse outcome in several cancer types. We recently demonstrated that overexpression of PODXL is an independent factor of poor prognosis in colorectal cancer (CRC). The aim of this study was to validate these results in two additional indepen

Past, present and future state of the biogeochemical Si cycle in the Baltic Sea

The Baltic Sea is one of many aquatic ecosystems that show long-term declines in dissolved silicate (DSi) concentrations due to anthropogenic alteration of the biogeochemical Si cycle. Reductions in DSi in aquatic ecosystems have been coupled to hydrological regulation reducing inputs, but also with eutrophication, although the relative significance of both processes remains unknown for the observ