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Levodopa--carbidopa intestinal gel for treatment of advanced Parkinson''s disease

Levodopa is the mainstay of Parkinson''s disease (PD) treatment, but is often eventually associated with disabling motor complications in patients with advanced PD. The inability of perorally administered levodopa to provide more physiologic continuous dopaminergic stimulation (CDS) is a leading hypothesis to explain these complications. To investigate the cumulative efficacy and safety, and re-ev

Investigating the kinetics of the enzymatic depolymerization of polygalacturonic acid in continuous UF-Membrane reactors

A stirred tank membrane reactor is used to study the kinetics of polygalacturonic acid (PGA) enzymatic hydrolysis. The reactor operates in semicontinuous configuration: the native biopolymer is loaded at the initial time and the system is continuously fed with the buffer. The effect of retention time (from 10 1 to 142 min) and membrane molecular weight cutoff (from I to 30 kDa) on the rate of perm

Wireless Esophageal pH Monitoring Is Better Tolerated than the Catheter-Based Technique: Results from a Randomized Cross-Over Trial.

OBJECTIVES: Esophageal pH monitoring using a wireless pH capsule has been suggested to generate less adverse symptoms resulting in improved patient acceptance compared with the catheter-based method although evidence to support this assumption is lacking. The aim of this study was to evaluate and compare the subjective experience of patients undergoing both techniques for esophageal pH monitoring.

Impact of southern Baltic sea-level changes on landscape development in the Verkeån River valley at Haväng, southern Sweden, during the early and mid Holocene

I Hanöbukten utanför Haväng i sydöstra Skåne finns välbevarade undervattenslämningar från ett mesolitiskt landskap med rester av träd och sediment avsatta i å- och lagunmiljö. Arkeologiska fynd av bland annat stationära fiskeredskap och en hackyxa av horn har gjorts. Landskapet formades under lågvattenperioderna under Yoldiahavet (11 700-10 800 cal BP) och Littorinahavets första fas (9800-8500 calIn the Hanö bay off the coast at Haväng in SE Scania, southern Sweden, a submerged and well-preserved Mesolithic landscape is found, including remains of trees, river and lagoon sediments, and archaeological artefacts such as an antler pick axe and stationary fishing constructions. The landscape was formed during the Yoldia Sea (11,700-10,800 cal BP) and Initial Littorina Sea (9800-8500) low-water

Mass movements as contamination carriers in surface water systems : Swedish experiences and risks

Populärvetenskaplig sammanfattning: Naturkatastrofer är något som Sverige är relativt förskonat från. Massrörelser, alltså markrörelser i jordtäcke eller berg såsom lerskred, slamströmmar och bergras, är däremot relativt vanligt förekommande runt om i landet. Det är dessutom så att frekvensen av den här typen av fenomen förväntas öka i Sverige till följd av framtida klimatförändringar. De områdenRecent studies indicate a widespread but largely overlooked hazard of contaminant mobilisation and transport in connection to mass movement activity into surface water systems in Sweden. Concerns are exacerbated by predicted effects of climate change, which suggest national increases in rates of precipitation, pore water pressures, run -off, erosion and mass movement occurrence. In this study, the

Fällande dom till varje pris? En analys av penningtvättsbrottet och dispositionsförbudet ur ett rättssäkerhets- och effektivitetsperspektiv

Penningtvätt utgör ett problem för samhällsekonomin, då det innebär ett hot mot det finansiella systemet om pengar med kriminellt ursprung hamnar i den legala ekonomin. Sveriges skydd för att kriminella tillgångar tvättas i den legala ekonomin har visat sig ineffektivt. Financial Action Task Force on money laundering har påpekat bristerna i svensk rätt och rekommenderat åtgärder då det inte finns If money with illicit origins enters into circulation in the financial system it poses a threat to the mechanisms of the financial system. Financial Action Task Force have concluded that the Swedish legal requirements for combating money laundering is insufficient, and the organisation have advised Swedish authorities to effectuate preventive measures. Therefore, the Swedish legal system is not co

Semantic Change in Words Loaned to Swedish

This thesis examines the diachronic semantic development in terms of metonymization and metaphorization for 30 nouns loaned into the Swedish language between the 13th and 20th centuries from a cognitive-semantic point of view. Through the framework of Lexical Meaning as Ontologies and Construals (LOC) combined with a study of the occurrence of metaphorization, metonymization, widening and narrowin

En exklusiv vågbrytare mot den positiva integrationens svallvågor? – En studie av direktiv 2009/81/EG:s påverkan på tillämpningen av artikel 346(1)a FEUF

Den europeiska gemenskapen inom försvars-och säkerhetsfrågor rör sig allt mer ifrån transnationellt samarbete mot federal integration. Parallellt med denna utveckling identifieras på EU-nivå i dagsläget dessutom en rad nya säkerhetspolitiska utmaningar som både unionen och medlemsstaterna till stor del är överens om att hantera gemensamt. Likväl förekommer också att krav ställs på mer nationellt sThe European Community in the fields of defence and security is at large moving further and further from transnational cooperation towards federal integration. In line with this development, a number of new security policy challenges have today been identified at EU level and both the EU and a majority of its member states agree that they need to be addressed jointly. Nevertheless, demands from me

Efficient Drone Control in Emergency Situations

This master’s thesis has been conducted in collaboration with Remote Aero. The aim is to determine important design principles when developing an interface to be used for drone control in emergency situations. To determine the end user, an interview was conducted with the stakeholder. The end user was defined as an individual that works as a sea rescue volunteer at the Swedish Sea Rescue Society w

Detection of Hearing Loss in Audiological Frequencies from Transient Evoked Otoacoustic Emissions

Transient evoked otoacoustic emissions (TEOAEs) have been analyzed for objective assessment of hearing function and monitoring of the influence of noise exposure and ototoxic drugs. This paper presents a novel application of the Hilbert-Huang transform (HHT) for detection and time-frequency mapping of TEOAEs. Since the HHT does not distinguish between signal and noise, it is combined with ensemble

Potential of Hyperion imagery for simulation of MODIS NDVI and AVHRR-consistent NDVI time series in a semi-arid region

Long time series of satellite remotely sensed Normalized Difference Vegetation Index (NDVI) as an indicator of vegetation greenness can be used in a broad range of research topics such as climate change, vegetation dynamics and desertification monitoring. The first phase of this study tests a practical method using Hyperion imagery onboard on Earth Observing-1 (EO1) spacecraft for simulation of MO

On the Hunt for Outdoors’ Next (Circular) Top Model - Investigating Ex-ante Assessment Tools for Circular Business Models in the Outdoor Fashion Industry

Different actors identified the circular economy (CE) as a solution to tackle global environmental challenges and foster sustainable growth. Transitioning to CE requires new circular business models (CBM), which create, capture, and deliver value, based on the principles of the CE. It is, however, a challenging process for companies see through the wide variety of CBM types and to identify which C

Berättelser som berör: En generationsjämförelse av emotionell storytelling i reklam

Titel: Berättelser som berör - en generationsjämförelse av emotionell storytelling i reklam Seminarie datum: 2025-06-03 Kurs: FEKH29 Examensarbete i marknadsföring på kandidatnivå, 15 hp Författare: Josefina Gerdes, Seth Knöchel, Sara Palmquist Handledare: Clara Gustafsson Nyckelord: Storytelling, Emotionellt värde, Generation Z, Generation X, konsumentbeteende Forskningsfråga: Hur skapar storytelTitle: Stories that move - A generational comparison of emotional storytelling in advertising Seminar date: 2025-06-03 Course: FEKH29 Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 Credits Authors: Josefina Gerdes, Seth Knöchel, Sara Palmquist Advisor: Clara Gustafsson Key words: Storytelling, Emotional value, Generation Z, Generation X, Consumer behavior Rese

The Inconspicuous Self: Exploring the Role of Inconspicuous Consumption within Luxury Services

Purpose: The relationship between inconspicuous consumption and consumers’ self-identities within luxury hospitality services has been largely overlooked, which calls for further investigation. Consequently, this study aims to explore the understanding of the relationship between the phenomena of inconspicuous luxury consumption of hospitality services and individuals’ self-identities. Methodolog

Klimathot eller dagsbot? – En rättsfilosofisk analys av civil olydnad till förmån för klimatet

De utmaningar som dagens och kommande generationer står inför, till följd av klimatförändringarnas konsekvenser, har inga motsvarigheter i historien. Därför utmanas vårt tänkande och agerande från grunden. Som en följd av detta finns en rörelse som försöker påverka politiken och samhället i en mer hållbar riktning: klimataktivisterna. I oktober 2024 friades en klimataktivist av Stockholms tingsrätThe challenges faced by current and future generations as a result of the impacts of climate change are unprecedented. Therefore, our modes of thinking and acting are being fundamentally challenged. As a result, a new climate movement has emerged, calling on politicians to ensure sustainable policies and societies. In October 2024, a climate activist was acquitted by the Stockholm District Court o

Tilt anisoplanatism in laser-guide-star-based multiconjugate adaptive optics. Reconstruction of the long exposure point spread function from control loop data

A method is presented for estimating the long exposure point spreadfunction (PSF) degradation due to tilt anisoplanatism in alaser-guide-star-based multiconjugate adaptive optics systems fromcontrol loop data. The algorithm is tested in numerical Monte Carlosimulations of the separately driven low-order null-mode system, and isshown to be robust and accurate with less than 10 relative error inboth

Does PHS Model Predict Acceptable Skin and Core Temperatures While Wearing Protective Clothing.

Mathematical modeling is very important when experimental settings with human subjects are restricted to thermal limits necessary to protect the individual. The predicted heat strain (PHS) model has been published AS ISO 7933 for about six years. It describes a method for predicting the sweat rate and internal core temperature that the human body will develop in response to the working conditions.

Visibility Clothing for Children

This degreework was initiated by a brief email send form the department of design science at Lund Institute of Technology, Lund University. It was an invitation from the company Reflectil Sverige AB about their interest to renew their selection of non-professional high visibility garment. The companies demand was to broaden their selection of nonprofessional high visibility garment. They wanted to

Interactive tool support for domain-specific languages

Domain-specific languages are used in numerous problem domains, e.g. database handling, robot programming and numerical calculations. The main advantage of using such languages is the ease with which a problem within the domain can be expressed in the language. The resulting programs are easier to debug and maintain, and consist of higher quality code since the language constructs are close to the

Spin ∼ 60 ℏ in 156Dy : Competition between collective and terminating structures at very high-spin

The highest-spin discrete states (I ∼ 60 ℏ and Ex ∼ 30 MeV) in normal deformed nuclei have been observed in the rare-earth isotope 156Dy using the 124Sn(36S,4n) reaction in conjunction with the GAMMASPHERE spectrometer. The positive parity yrast sequence appears to evolve smoothly from a prolate (collective) towards an oblate (non-collective) shape, in contrast to the sudden shape change observed