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α-Chymotrypsin immobilized on celite catalyzing a kinetically controlled dipeptide synthesis reaction in acetonitrile medium showed an odd behavior in response to additions of triethylamine to the reaction mixture. This base is used to deprotonate the nucleophilic reagent, l-alaninamide hydrochloride, in order to increase its nucleophilicity and solubility. However, the enzyme performance is appar

BioMed CentralBMC Biotechnology ss Open AcceResearch article Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants Troels T Nielsen1,2, Johan Jakobsson1, Nina Rosenqvist1 and Cecilia Lundberg*1 Address: 1CNS Gene Therapy Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Sciences, Lund University, BMC A11, S-221 84 Lund,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_bmc_biotechnology.pdf - 2026-05-23

On the Role of Materiality Brandstationen, Helsingborg December 6th, 2023, 9:30-17:00 Welcome on December 6th, to a one-day seminar where we will be focusing on materiality from different perspectives. We are interested in the role of materiality, how materiality relates to place, body, emotions and senses, how it relates to practices, methods and creativity. When: December, 6th, 2023, 9:30-17:00

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2023-11/CROCUS%20Seminar%20on%20Materiality%20Dec%206,%202023%20-%20Program.pdf - 2026-05-23

Neoliberalism, as a loosely defined set of political beliefs, calls for more individual freedom and autonomy, resulting in increased responsibility for each person to address major societal issues. ‘Individualization’ is the process by which responsibility for addressing major environmental issues such as climate change is placed on individuals. In this thesis I investigate whether individualizati

Background The perception of surgery as expensive and complex might be a barrier to its widespread acceptance in global health efforts. We did a systematic review and analysis of cost-effectiveness studies that assess surgical interventions in low-income and middle-income countries to help quantify the potential value of surgery. Methods We searched Medline for all relevant articles published betw

Background: Botulinum toxin A (BTX-A) has been used to reduce spasticity in children with cerebral palsy (CP) for decades. The purpose of this study was to analyze to what extent BTX-A treatment was used to treat spasticity in a total population of children with CP. We investigated 1) the use of BTX-A in relation to age, sex, and Gross Motor Function Classification System (GMFCS) level, 2) the mos

Postal address Box 7080 Visiting address Tycho Brahes väg 1 Telephone +46 46 222 00 00 E-mail fredrik.andersson@ehl.lu.se Website www.lusem.lu.se Depar tm ent of Inform at ics General Syllabus for Third-Cycle Studies in Informatics for the Degree of Doctor at Lund University School of Economics and Management The syllabus for third-cycle studies in Informatics was adopted by the Board of the Schoo

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-01/FU-asp-inf-en.pdf - 2026-05-23

INTRODUCTION: Osteoporosis of the axial skeleton is a known complication of ankylosing spondylitis (AS), but bone loss affecting the peripheral skeleton is less studied. This study on volumetric bone mineral density (vBMD) and bone microarchitecture in AS was conducted to compare peripheral vBMD in AS patients with that in healthy controls, to study vBMD in axial compared with peripheral bone, and

The purpose of this paper is to study the determination of annual changes in the money wage rate and in the price level in Sweden during the period 1922–1971. We have chosen to examine such a long span of years in order to make comparisons between various time periods and to investigate to what extent a given set of explanatory variables can account for the movements in wages and prices during the

BACKGROUND:The need for instruments that can assist in detecting the prodromal stages of stress-related exhaustion has been acknowledged. The aim of the present study was to evaluate whether the Lund University Checklist for Incipient Exhaustion (LUCIE) could accurately and prospectively detect the onset of incipient exhaustion and to what extent work stressor exposure and private burdens were ass

The method presented in this paper is invented to address the problem of episodic memory in participants with highly restricted verbal abilities, 15-month-olds in this case. Here, we refer to episodic memory defined as a mind/brain system with three main responsibilities: to encode, to store and to recall individual memories. Episodic memory system requires three additional capacities, which make

Variations in molybdenum isotopic composition, spanning the range of similar to 2.3 parts per thousand in the terms of Mo-97/Mo-95 ratio, have been measured in sediment cores from three lakes in northern Sweden and north-western Russia. These variations have been produced by both isotopically variable input of Mo into the lakes due to Mo isotopic heterogeneity of bedrock in the drainage basins and

OBJECTIVE: Imaging follow-up (FU) after endovascular aneurysm repair (EVAR) is usually performed by periodic contrast-enhanced computed tomography (CT) scans. This study aims to evaluate the effectiveness of CT-FU after EVAR. METHODS: In this study, 279 of 304 consecutive patients (261 male, aged 74 years (interquartile range (IQR): 70-79 years) with a median abdominal aortic aneurysm (AAA) diamet

OBJECTIVES: To determine the ability to correctly identify Cesarean section scars, to estimate the prevalence of defective scars, and to determine the size and location of scar defects by transvaginal ultrasound imaging. METHODS: Two hundred and eighty-seven women underwent transvaginal ultrasound examination 6-9 months after delivery: 108 had undergone one Cesarean section, 43 had had two Cesarea

Background Carrying the cyclin-dependent kinase inhibitor 2A (CDKN2A) germline mutations is associated with a high risk for melanoma. Penetrance of CDKN2A mutations is modified by pigmentation characteristics, nevus phenotypes, and some variants of the melanocortin-1 receptor gene (MC1R), which is known to have a role in the pigmentation process. However, investigation of the associations of both

The present study investigates spatial properties of atrial fibrillation (AF) by analyzing VCG loops synthesized from 12-lead ECGs. During intervals with ventricular activity, the atrial signal is extracted using spatiotemporal QRST cancellation, thus making continuous f-wave analysis possible. Spatial properties are characterized through joint analysis of successive fixed-length signal segments,

To optimize productivity and working-life quality, it is important to understand and utilise the connections between productivity and working environment. Culture and the state of the market may affect the strength of these connections. However, in order to ensure flexibility and quality in products and services, it may be useful to have motivated, skilled and responsible coworkers at all levels.