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Background: In light of increasing therapeutic options, risk stratification of advanced cardiac transthyretin amyloidosis (ATTR-CA) is gaining clinical importance to avoid ineffective treatments. Liver stiffness as a marker of hypervolemia and hepatic congestion might predict mortality in advanced ATTR-CA and allow to identify patients at highest risk. Methods: Proven ATTR-CA patients underwent re

Objective: This study was undertaken to develop and characterize a multiplex immunoassay for detection of autoantibodies against peptides derived from proteins known to play a role in development of arthritis and that are also expressed in joints. Methods: We selected peptides from the human counterpart of proteins expressed in the joints, based on mouse models that showed these to be targeted by

Targeted temperature management (TTM) may moderate the injury from out-of-hospital cardiac arrest. Slowing the metabolism has been a suggested effect. Nevertheless, studies have found higher lactate levels in patients cooled to 33°C compared with 36°C even days from TTM cessation. Larger studies have not been performed on the TTM's effect on the metabolome. Accordingly, to explore the effect of TT

Background: The solid-state cadmium-zinc-telluride (CZT) gamma camera for myocardial perfusion single-photon emission computed tomography (MPS) has theoretical advantages compared to the conventional gamma camera technique. This includes more sensitive detectors and better energy resolution. We aimed to explore the diagnostic performance of gated MPS with a CZT gamma camera compared to a conventio

Background - Correct blood group typing is the cornerstone of transfusion medicine. In patients whose gastrointestinal wall is compromised, bacterial enzymes can cause deacetylation of blood group A, converting N-acetylgalactosamine to galactosamine, which resembles the B-defining galactose. This acquired B (acqB) phenomenon, first described 1959, can lead to blood grouping errors. Herein, we expl

Tirzepatide is a dual GIP and GLP-1 receptor co-agonist which is approved for glucose-lowering therapy in type 2 diabetes. Here, we explored its effects on beta cell function, insulin sensitivity and insulin-independent glucose elimination (glucose effectiveness) in normal mice. Anesthetized female C57/BL/6 J mice were injected intravenously with saline or glucose (0.125, 0.35 or 0.75 g/kg) with o

BACKGROUND: The introduction of modern chemotherapy a decade ago has led to increased use of neoadjuvant therapy (NAT) in patients with pancreatic ductal adenocarcinoma (PDAC). A recent North American study demonstrated increased use of NAT and improved operative outcomes in patients with PDAC. The aims of this study were to compare the use of NAT and short-term outcomes in patients with PDAC unde

IntroductionCardiac surgery is required in up to half of the patients with infective endocarditis (IE). Positive valve cultures have been associated with higher in-hospital mortality. The aims were to identify risk factors for positive valve cultures and its relation to outcome.MethodsPatients subjected to heart valve cultures due to surgery for IE in Skåne University Hospital, Lund, between 2012

Objective: To determine the influence of serum sodium on physical, psychologic and sexual function. Methods: This is a cross-sectional survey on 3340 community-dwelling men aged 40–79 years from a prospective cohort study in eight European countries, the European Male Ageing Study (EMAS). Participants filled-out the Short Form-36 (SF-36), the Physical Activity Scale for the Elderly (PASE), and the

AIMS: To investigate the individual characteristics, causes and circumstances around deaths in stimulant use, and to examine how individuals who died with stimulants in their body differ from individuals who died with opioids in their body.METHODS: This study includes individuals who died during the years 2000-2018 and underwent a forensic autopsy at Forensic Medicine in Lund, Skåne County, Sweden

Background. Poor maternal self-rated health in healthy women is associated with adverse neonatal outcomes, but knowledge about self-rated health in pregnant women with congenital heart disease (CHD) is sparse. This study, therefore, investigated self-rated health before, during, and after pregnancy in women with CHD and factors associated with poor self-rated health. Methods. The Swedish national

Objectives: To evaluate outcomes of management without surgical revascularization in patients with acute lower limb ischemia (ALI) in a population-based setting. Design: Retrospective observational population-based study. Materials: Patients from Malmö, Sweden, hospitalized for ALI between 2015 and 2018. Methods: In-hospital, surgical, radiological, and autopsy registries were scrutinized for desc

In humans, resting cerebral perfusion, oxygen consumption and energy metabolism demonstrate large intersubject variation regardless of methodology. Whether a similar large variation is also present longitudinally in individual subjects is much less studied, but knowing the time variance in reproducibility is important when designing and interpreting longitudinal follow-up studies examining brain p

Aims: Type 2 diabetes (T2D) patients with a clinical phenotype characterized by a high degree of insulin resistance are at increased risk of chronic kidney disease (CKD). We previously demonstrated that the endothelin receptor antagonist (ERA) atrasentan reduced insulin resistance in T2D. In this study, we compared the effect of atrasentan on insulin resistance across different phenotypic clusters

Microsoft Word - Kandidatuppsats - Samhällsviktig verksamhet och kommunal planering-2.docx Samhällsviktig verksamhet och kommunal planering En fallstudie av två skånska kommuner Ulrike Donnerhack 2016-05-27 Institutionen för kulturgeografi och ekonomisk geografi SGEL36, Examensarbete inom Kandidatprogrammet i samhällsplanering Vårterminen 2016 Handledare: Nicklas Guldåker 1 2 Abstract Our modern s

https://www.cencip.lu.se/sites/cencip.lu.se/files/donnerhack_2016_samhallsviktig_verksamhet_och_kommunal_planeri.pdf - 2026-04-25

Rapport vecka 35 (publicerad 2020-09-02) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 2 Aktuell status 2 10 postnummerområden med högst uppskattad förekomst den 31 augusti . . . . . . . . . . . . . . 4 10 postnummerområden med lägst uppskattad förekomst den 31 augusti . . . . . . . . . . . . . . . 6 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka35_coss.pdf - 2026-04-25

Real estate investigation Geocentrum I and II Co-location for INES, Geology and CEC 230607 The location Ekologihuset Fysicum 8 00 m Geocentrum I Geocentrum IV Geocentrum II ATF N-fak Befattningskategori Antal anställningar Antal anställda omorganisation* Svälltal gästforskare** Egna rum Delat rum 2p Delat rum 4- 6p Professor 24 29 1 29 Lektor 27 30 30 Meriteringsanställning BULAR 16 18 9,0 9 Adjun

https://www.science.lu.se/internal/sites/science.lu.se.internal/files/2023-06/basic-premises-review-7-june-2023.pdf - 2026-04-25

Rapport vecka 32 (publicerad 2020-08-12) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 2 Aktuell status 2 10 postnummerområden med högst uppskattad förekomst den 10 augusti . . . . . . . . . . . . . . 4 10 postnummerområden med lägst uppskattad förekomst den 10 augusti . . . . . . . . . . . . . . . 6 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka32_coss.pdf - 2026-04-25

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka34_coss.pdf - 2026-04-25

en_TN08_aScientistsJob Teacher  notes  on  “A  scientist’s  job”  |  page  1  of  5       Notes for teachers on  module  8:     A scientist’s job     What  does  a  scientist  do  all-­‐day  long?  Stare  at  a  whiteboard  with  equations  or  mix  colourful,  wild  steaming   liquids  while  waiting  for  an  explosion?       School  children  as  well  as  adults  will  usually  recognize  that

https://www.nrcf.lu.se/sites/nrcf.lu.se/files/2025-05/en_TN08_aScientistsJob.pdf - 2026-04-25