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Skyldighet att höra, men ingen plikt att lyssna? Om barns rätt till delaktighet

Barnets bästa ska vara avgörande för alla frågor om vårdnad, boende och umgänge. Barnets åsikter är en viktig del i bedömningen och som regel får barn, om det inte bedöms som olämpligt, komma till tals. Det är dock långt ifrån självklart att deras åsikter faktiskt påverkar utgången. Ett barn som motsätter sig att träffa en förälder kan ändå få umgänge beslutat av domstol trots att umgänge enligt lThe best interests of the child should be decisive in all matters concerning custody, residence and visitation. The child’s views are an important part of this assessment, and children are generally given the opportunity to express their opinions, unless it is deemed inappropriate. However, it is far from certain that these opinions actually influence the outcome. Even if a child opposes visiting

Bench-scale Fire Stability Assessment of Cross-Laminated Timber

As mass timber construction gains momentum worldwide, cross-laminated timber (CLT) has emerged as an important material in the built environment. However, the combustible nature of wood presents challenges and fire safety concerns, and a key interest with respect to CLT is the adhesive bond line. CLT is commonly used in ceiling configuration, and current fire stability evaluations rely predominant

Indigenous Rights and Environmental Imperatives: A Normative Analysis of Green Mining

This essay explores the ethical dilemma surrounding the construction of green mines on indigenous lands and seeks to determine whether such actions can be justified. The aim is to show that a prioritisation between two seemingly good things is not always a given. Using a normative study framework, the research investigates a conflict of value between different interpretations of the value of the G

Feasibility of an interpreter-mediated neuropsychological test battery for trauma-affected refugees

Background: Cognitive impairment in trauma-affected refugees is often unassessed due to the absence of suitable cross-cultural neuropsychological measures, the high prevalence of psychiatric symptoms, and the need for interpreter mediation. This poses both a clinical challenge and a health inequality for trauma-affected refugees who are left without access to much needed rehabilitation. Untreated

Retrospectively synchronized time-resolved ventricular cine images from 2D real-time exercise cardiac magnetic resonance imaging

Breath-hold ECG-gated cardiovascular magnetic resonance (CMR) imaging is challenging during exercise due to motion, ECG-problems, and lengthy scans. To facilitate time-resolved volumetric measures from exercise-CMR, we aimed to develop a method for constructing time-resolved ventricular cines from real-time free-breathing exercise-CMR. Time-resolved ventricular cines were semi-automatically constr

Translation and Validation of the Swedish Patient-Rated Ulnar Nerve Evaluation in Ulnar Nerve Entrapment

Background: A Swedish version of the Patient-Rated Ulnar Nerve Evaluation (PRUNE-S), a patient-reported outcome measure for ulnar nerve entrapment, was created, according to cross-cultural adaptation guidelines, and reliability, validity, and responsiveness were evaluated. Methods: In total, 43 patients (mean [SD] age, 49 [16] y; 54% men) were consecutively examined, including the PRUNE-S (retest:

Prevalence and Predictors of Achieving Sustained Remission in Psoriatic Arthritis : A Swedish Nationwide Registry Study

OBJECTIVE: To estimate the prevalence and predictors of sustained remission (SR) in patients with psoriatic arthritis (PsA) receiving biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) in Sweden. METHODS: All patients with PsA initiating b/tsDMARDs and who were registered in the national Swedish Rheumatology Quality Register (SRQ) from April 1999 to December 2019 wer

Impact of surgical specialization on long-term survival after emergent colon cancer resections

Background: The impact of surgical specialization on long-term survival in patients undergoing emergent colon cancer resections remains unclear. Method: A retrospective analysis was conducted on all patients who underwent emergent colon cancer resections at a secondary care hospital between 2010 and 2020. The most senior surgeon performing the procedures was classified as colorectal surgeon (CS) o

Climate-Driven Increase in Transmission of a Wildlife Malaria Parasite Over the Last Quarter Century

Climate warming is expected to influence the prevalence of vector-transmitted parasites. Understanding the extent to which this is ongoing, or has already occurred, requires empirical data from populations monitored over long periods of time, but these studies are sparse. Further, vector-disease research involving human health is often influenced by disease control efforts that supersede natural t

Experimental Study of Glow Plug Assisted Methanol Compression Ignition

Methanol can be produced renewably and used in compression ignition (CI) engines as a replacement for fossil diesel. However, methanol is a low cetane fuel, creating challenges in achieving stable operation, particularly at low load. One potential solution is through surface ignition via a glow plug. In this work, experiments were conducted on a methanol-fueled 2.1 L single cylinder engine instrum

Genetically predicted serum urate and cancer risk : a Mendelian randomization study

Objective: To evaluate the causal effect of genetically predicted serum urate (SU) levels on the risk of overall and major site-specific cancers in individuals of European ancestry, using Mendelian randomization (MR) analysis. Method: Data from two population-based cohorts from southern Sweden, the Malmö Diet and Cancer Study (MDCS) and Malmö Preventive Project (MPP), and summary-statistics data f

Cardiovascular, respiratory and splenic responses to rebreathing and apnoea during exercise

We investigated integrative physiological responses to eupnoeic exercise (EX), rebreathing exercise (RB), dynamic apnoea (DA) and dynamic apnoea with cold-water face immersion (DAFI) in 20 healthy participants. Trials involved non-steady-state cycle exercise at 60 W for an average duration of 66 s. With increases in heart rate and stroke volume, EX and RB increased cardiac output compared with bas

Direct letters to relatives at risk of hereditary cancer—a randomised trial on healthcare-assisted versus family-mediated risk disclosure

Observational studies suggest that direct contact from healthcare to at-risk relatives may increase genetic counselling (GC) uptake as compared to family-mediated risk disclosure, but randomised controlled trials (RCTs) are lacking. This study assessed whether the offer of direct letters to relatives at risk of hereditary breast and ovarian cancer (HBOC) or Lynch syndrome increases GC uptake compa

Comorbidities and mortality in subgroups of adults with diabetes with up to 14 years follow-up : a prospective cohort study in Sweden

Background: Subgroups of adult-onset diabetes, namely severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), and mild obesity-related diabetes (MOD) or mild age-related (MARD) diabetes, have been defined with clinical variables and a machine-learning approach. Our aim was to describe their long-term outcomes and mortality. Methods: In

Peripheral Serotonin and CYP2D6: Candidate Biomarkers of Antidepressant Treatment Response

Background and aimMany patients with depressive disorders do not improve with first-line treatment with selective serotonin inhibitors (SSRIs). Adverse drug reactions (ADRs) are common. However, there are no reliable methods to predict treatment response.The general aim of this thesis was to investigate the role of peripheral serotonin and the polymorphic CYP2D6 gene as potential biomarkers of tre

The effect of birth order on children's time use

Recent research shows that birth order affects human capital outcomes, yet there is limited empirical evidence on the underlying mechanisms. This study examines the effect of birth order on children's time use across activities that are important for human capital development. Using detailed time-use diaries of Australian children aged 2–15, we find that within families with two or three children,

A Comparison of Tissue Handling Forces Between a Novel Suturing Device for Standardised Abdominal Wall Closure and Manual Needle-Driver Suturing

Introduction: Suturing is a fundamental component of surgical procedures, wherein training emphasises the significance of gentle tissue handling. The suturing process involves the pressure exerted by the forceps onto the tissue, as well as the medial traction force applied to stabilise the tissue during the needle bite. This study examined the forces involved in tissue handling during suturing, co

Förekomst och typ av underkroppsskador mellan unga kvinnor och män inom ungdomsfotboll i Sverige

Bakgrund Fotboll är Europas största idrott bland både unga och vuxna. För ungdomar innebär regelbunden träning både fysiska och psykiska hälsofördelar. Om man drabbas av en skada kan dessa hälsovinster gå förlorade. Syfte Syftet med studien var att kartlägga och jämföra förekomst och typ av underkroppsskador mellan unga kvinnor och män i en begränsad grupp ungdomsfotbollsspelare. Vilka skadeskilln

Choice of fixative affects programmed death-ligand 1 expression in cell blocks from pleural effusions with metastatic pulmonary adenocarcinoma

Background: Programmed death-ligand 1 (PD-L1) immunocytochemical (ICC) analysis of cell blocks (CBs) has recently emerged in clinical practice. Unlike standardized immunohistochemistry on formalin-fixed, paraffin-embedded tissues, cytology involves various preparation methods and fixatives. This study investigated how various fixatives influence PD-L1 immunoreactivity in CBs from malignant pleural

Risk of Infection Before and After Thiopurine Therapy in Inflammatory Bowel Disease : A Population-Based Study

GOALS: To assess the incidence, type, and severity of infections in patients with IBD before and after starting thiopurine therapy.BACKGROUND: Thiopurines have been used for decades in the treatment of inflammatory bowel disease (IBD), yet real-world data regarding the extent and types of infections associated with their use are scarce.STUDY: We included all thiopurine-naive adults with IBD who in