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The equivocal opposite effects of lower and higher body mass index at diagnosis on radiographic joint damage progression in early rheumatoid arthritis : an inception cohort study over 15 years

Objective To investigate the effect of Body Mass Index (BMI) on long-term radiographic damage in an inception rheumatoid arthritis (RA) cohort. Methods The study population, n=1813, originated from the observational Better AntiRheumatic FarmacoTherapy cohort. X-rays of hands and feet at inclusion, 1, 2, 5, 8 and 15 years were quantified for erosion score (ES), joint space narrowing (JSN) and the s

The association between animal protein, plant protein, and their substitution with bladder cancer risk : a pooled analysis of 10 cohort studies

Purpose: Although total dietary protein intake has been associated with bladder cancer (BC) risk, the effect of the origin (plant or animal) and the substitutions remain to be understood. This study aimed to investigate the effect of total dietary protein, animal-based protein, plant-based protein, and their substitutions with each other on the risk of BC using a pooled analysis of 10 cohort studi

Subparalyzing Doses of Rocuronium Reduce Muscular Endurance without Detectable Effect on Single Twitch Height in Awake Subjects

Purpose. To test the hypothesis that a low-dose rocuronium acts mainly by means of reducing muscular endurance rather than by reducing momentary force. Methods. In a randomized placebo-controlled double-blinded study, eight healthy volunteers were studied in two sets of experiments. In the first set, the subjects made a sustained maximum effort with the dominant hand for 80 seconds while squeezing

Patterns of normal change in cervical length and width during pregnancy in nulliparous women: a prospective, longitudinal ultrasound study

OBJECTIVES: To determine what constitutes normal changes in the uterine cervix visible at transvaginal ultrasound examination from 24 gestational weeks until delivery in nulliparous women delivering at term. DESIGN: Cervical length and width were measured using transvaginal ultrasound, and the inner cervical os was assessed as being closed or open every 2 weeks from gestational week 24 until deliv

Application of Laser-based Diagnostics to a Prototype Gas Turbine Burner at Selected Pressures

Popular Abstract in English There is a natural tendency to take advantage of the most convenient energy source available. In this usage, convenient may mean most abundant, easiest to harvest or simplest to handle. Convenient will also correspond to cheapest in many instances. However, some consider it a responsibility to think of the long term costs of the energy we use. No form of energy is free The matured laser-diagnostic techniques of planar laser-induced fluorescence (PLIF) and particle image velocimetry (PIV) were applied to a prototype gas turbine burner operating on various fuels. The work was performed to provide verification of computational fluid dynamic (CFD) models of the combustion of atypical fuels in a gas turbine combustor. The burner was operated using methane and three s

Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015 : a systematic analysis for the Global Burden of Disease Study 2015

BACKGROUND: Chronic obstructive pulmonary disease (COPD) and asthma are common diseases with a heterogeneous distribution worldwide. Here, we present methods and disease and risk estimates for COPD and asthma from the Global Burden of Diseases, Injuries, and Risk Factors (GBD) 2015 study. The GBD study provides annual updates on estimates of deaths, prevalence, and disability-adjusted life years (

Long-term Safety and Efficacy of Reslizumab in Patients with Eosinophilic Asthma

Background In placebo-controlled trials, reslizumab, an anti-IL-5 monoclonal antibody, significantly reduced asthma exacerbations and improved lung function and asthma control in patients with eosinophilic asthma. Objective This open-label extension study evaluated safety and efficacy of reslizumab for up to 24 months. Methods After participation in 1 of 3 placebo-controlled, phase III trials in m

Higher education and more physical activity limit the development of obesity in a Swedish rural population The Skaraborg Project.

Objective:To investigate the prevalence and the secular trends of obesity in a rural Swedish community with emphasis on the association with socioeconomic status and lifestyle.Design:The Skaraborg Project cross-sectional population surveys were conducted in Vara, a rural community in the southwest of Sweden, every fifth year between 1977 and 2002.Subjects:A total of 3365 residents (1634 men and 17

Heka22.3 schema miljo- och utvecklingssociologi vt 2018

Schema miljö- och utvecklingssociologi VT 2018 Miljö- och utvecklingssociologi, HEKA22:3, VT 2018 Kursansvarig lärare: Vasna Ramasar (VR) vasna.ramasar@hek.lu.se Övriga lärare: Andreas Malm (AM), Noura Alkhalili (NA), Mads Barbesgaard (MB), Henner Busch (HB) and Katherine Burlingame (KB) 1. Wednesday 21 mars kl 10-12, Rio VR: To live in denial. Introduction to environmental sociology Litteratur: N

https://www.keg.lu.se/sites/keg.lu.se/files/heka22.3_schema_miljo-_och_utvecklingssociologi_vt_2018.pdf - 2026-05-28

Disclosure of public documents and confidentiality

Lund University is a public authority. Just like all other Swedish public authorities, the University must adhere to the statutory principle of public access to official documents. This principle entails an obligation to disclose official documents on request to the public. Issues related to public access, such as the disclosure of official documents and secrecy, are normally handled at the depart

https://www.staff.lu.se/support-and-tools/legal-division/disclosure-public-documents-and-confidentiality - 2026-05-28

Kinetics of Swelling Applied on Gelatine

Svällningsstudier med gelatin Av: Victor Norgren, Lunds tekniska högskola, 2015-06-15 Introduktion Gelatin är en genomskinlig proteinbaserad biopolymer, som tillverkas av kollagen. Kollagen är bindningsvävnaden som fäster musklerna till benen i kroppen. Genom att t.ex. koka benknotorna kan man utvinna kollagenet som blir gelatin när det tillåts sätta sig igen. Gelatintrådarna behåller den spiralThis report is about the measurements of swelling gelatine films of different thickness and at different temperature. The research has been mainly focused on finding a suitable model. Results have shown that the new Pseudo-Sigmoidal Model (PSM) is superior to previous quasi-second order models such as the Robinson and Ofner model. It has also been shown that gelatine’s swelling can be divided into

The environmental implication of E-commerce in the food industry

The importance of E-commerce in the grocery and food retailing is growing and an increasing number of home delivery solutions are being studied. Some observers predict that the consumers will use e-commerce and home delivery services more and more in the future. However, these developments are affected by a number of problems, many of which are not completely understood. This thesis particularly f

Combustion Characteristics of MCV/LCV Fuels - A Numerical Chemical Kinetics Study at Gas Turbine Conditions

The purpose of this Master’s Thesis is to develop a model for numerical simulations in order to kinetically characterize different Medium Calorific- Low Calorific Value (MCV-LCV) fuel gas mixtures. Adding fuel components with a very low heating value or inert species affect the stability of the standard gas turbine combustor design. Siemens Industrial Turbomachinery (SIT) believes that increasing

Neutralizing antibodies and efficacy of interferon beta-1a - A 4-year controlled study

Objective: To determine the incidence and clinical significance of neutralizing antibody (NAb) formation in patients with relapsing multiple sclerosis ( MS) who participated in the European Interferon Beta-1a IM Dose-Comparison Study. Methods. Patients were randomized to treatment with interferon beta-1a (IFN beta-1a) 30 mu g or 60 mu g IM once weekly for up to 4 years. Serum samples obtained at b

Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive Impairment

Importance: Phase 3 trials of successful antiamyloid therapies in Alzheimer disease (AD) have demonstrated improved clinical efficacy in people with less severe disease. Plasma biomarkers will be essential for efficient screening of participants in future primary prevention clinical trials testing antiamyloid therapies in cognitively unimpaired (CU) individuals with initially low brain β-amyloid (

Juxtarenal endovascular therapy with fenestrated and branched stent grafts after previous infrarenal repair

Background: The treatment strategy for proximal aortic disease or type I endoleak after previous infrarenal repair has traditionally been open surgery. As endovascular treatment options with fenestrated and branched stent grafts increasingly rival open surgery for juxtarenal and pararenal aortic aneurysms, secondary proximal repair may similarly be performed endovascularly. Fenestrated stent graft

An extended swedish national adoption study of bipolar disorder illness and cross-generational familial association with schizophrenia and major depression

Importance: Information about how risk for bipolar disorder is transmitted across generations and how parental risk for bipolar disorder relates to their children's risk for schizophrenia and major depression is limited. Objective: To evaluate the sources of parent-offspring transmission of bipolar disorder and its familial cross-generational association with schizophrenia and major depression. De

Pregnancy-associated plasma protein-A2 levels are increased in early-pregnancy gestational diabetes : a novel biomarker for early risk estimation

Aim: To determine whether pregnancy-associated plasma protein-A2 levels are increased in early pregnancies complicated by gestational diabetes and whether gestation age influences levels. The possible use of pregnancy-associated plasma protein-A2 as a pre-screening biomarker to reduce the need for performing oral glucose tolerance tests in pregnant women was also investigated. Methods: Pregnant wo

Tumor markers. Consensus Conference on Diagnosis and Prognostic Parameters in Localized Prostate Cancer. Stockholm, Sweden, May 12-13, 1993

This chapter mainly deals with biochemical aspects on prostate specific antigen (PSA) and its clinical value. To a limited extent, also other tumor markers, which might be of importance in the evaluation of patients with prostate cancer are discussed. In serum, PSA exists in a free form or bound to antichymotrypsin. Interestingly, only 10% of PSA secreted from cancer cells seems to exist in a free