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Changes in self-perceived performance and satisfaction with performance of daily activities following interdisciplinary rehabilitation in people with late effects of polio

Background: People with late effects of polio (LEoP) may need rehabilitation to manage everyday life but knowledge of the benefits of interdisciplinary rehabilitation is limited.Objective: To evaluate changes in performance and satisfaction with performance of activities among people with LEoP following interdisciplinary rehabilitation.Methods: A pre-post retrospective study based on data on 102 p

Surgical management of necrotising enterocolitis in Sweden : A national cohort study

Aim: Necrotising enterocolitis (NEC) is the dominating surgical emergency in preterm neonates. The aims were to investigate indications, surgical management and mortality for surgically treated neonates with NEC. Methods: Data were retrieved from the Swedish Neonatal Quality Register for Swedish neonates with surgically treated NEC from 1 January 2017 to 31 December 2021. Diagnosis was validated b

Results of patch testing with five fragrance materials hitherto not tested : A dose-finding study in the clinical population

Background: Quantitative risk assessment (QRA) for skin sensitization is used to derive safe use levels of sensitising fragrance ingredients in products. Post-marketing surveillance of the prevalence of contact allergy to these ingredients provides relevant data to help evaluate the performance of these measures. Objectives: To determine a suitable patch test concentration for five fragrance mater

Association between human chorionic gonadotropin (hCG) levels and adverse pregnancy outcomes : A systematic review and meta-analysis

Human chorionic gonadotropin (hCG), a glycoprotein produced in the placenta, is crucial for a healthy pregnancy. We investigated the relationship between hCG levels and adverse pregnancy outcomes. We conducted a systematic review including studies measuring hCG blood levels in the first or second trimester, reporting on any of the 12 predefined adverse pregnancy outcomes with logistic regression-a

Peroxynitrite scavenger FeTPPS binds with hCT to effectively inhibit its amyloid aggregation

Human calcitonin (hCT) is an endogenous polypeptide commonly employed in treating bone resorption-related illnesses, but its clinical application is limited due to its high aggregation tendency. Metalloporphyrins are effective in suppressing amyloid fibrillation, positioning them as potential drug candidates for amyloidogenic disorders like Alzheimer's and type 2 diabetes. In this work, we investi

Human rights committee : Not only a committee on civil and political rights

Introduction. There is no water-tight division between different categories of human rights. In particular, it is important to note that although the project of transforming the 1948 Universal Declaration of Human Rights into treaty form culminated in separate Covenants including, on the one hand, civil and political Rights and, on the other hand, economic, social and cultural Rights, it did not r

The international covenant on civil and political rights

General issues Basic features The International Covenant on Civil and Political Rights (ICCPR) was adopted by the United Nations General Assembly in 1966, and, after the required number of ratifications, it entered into force on 23 March 1976. To a large extent the Covenant, together with the simultaneously adopted International Covenant on Economic, Social and Cultural Rights, codifies in the for

Nationwide Observational Case–Control Study of Risk Factors for Aerococcus Bloodstream Infections, Sweden

Risk factors for developing bloodstream infections (BSIs) caused by Aerococcus bacteria remain insufficiently examined. In this nationwide case–control study in Sweden, 19 of 23 clinical microbiological laboratories identified patients who had aerococcal BSIs during 2012–2016. We compared each of those index patients with 4 controls matched for age, sex, and county of residence. Overall, 588 episo

Climate governance at the fringes : Peri-urban flooding drivers and responses

There is a large body of scientific evidence on the climate crisis and flooding in urban areas. Extreme weather events are producing extensive property damage and loss of life and require new modes of flood governance. However, the climate crisis does not stop at the city limits: peri-urban areas have related but distinct flood challenges due to land use change, regulation, perceptions, and capaci

Impact of national holidays and weekends on incidence of acute type A aortic dissection repair

Previous studies have demonstrated that environmental and temporal factors may affect the incidence of acute type A aortic dissection (ATAAD). Here, we aimed to investigate the hypothesis that national holidays and weekends influence the incidence of surgery for ATAAD. For the period 1st of January 2005 until 31st of December 2019, we investigated a hypothesised effect of (country-specific) nation

Explaining the rise of populism in European democracies 1980–2018: The role of labor market institutions and inequality

ObjectivesThis article aims to find country-level factors that explain the rise of populist parties in European democracies. While populism is often connected to inequality, we not that right-wing populist parties tend to thrive on fear, including fear of job loss. If flexible labor markets mean that unemployment is dedramatized because finding a new job is easier, labor market flexibility could d

Mitochondrial biogenesis, telomere length and cellular senescence in Parkinson’s disease and Lewy body dementia

Progressive age is the single major risk factor for neurodegenerative diseases. Cellular aging markers during Parkinson’s disease (PD) have been implicated in previous studies, however the majority of studies have investigated the association of individual cellular aging hallmarks with PD but not jointly. Here, we have studied the association of PD with three aging hallmarks (telomere attrition, m

Impact of in situ NH3 pre-treatment of LPCVD SiN passivation on GaN HEMT performance

The impact on the performance of GaN high electron mobility transistors (HEMTs) of in situ ammonia (NH3) pre-treatment prior to the deposition of silicon nitride (SiN) passivation with low-pressure chemical vapor deposition (LPCVD ) is investigated. Three different NH3 pre-treatment durations (0, 3, and 10 min) were compared in terms of interface properties and device performance. A reduction o

Tramadol misuse in treatment-seeking adolescents and young adults with problematic substance use – Prediction of treatment retention

Non-medical prescription use of opioids (NMPUO) is a public health concern worldwide. Recently, tramadol misuse is increasing, but the systematic research of misuse of this specific opioid is limited. This study set out to assess the relationship between tramadol use and completion of treatment for substance use among adolescents and adults ≤ 25 years in an outpatient clinical setting. A retrospec

Feasibility and acceptability of human papillomavirus self-sampling in a semi-urban area in northern Tanzania

Objective: To assess the feasibility and acceptability of HPV self-sampling in Arusha region, northern Tanzania, because the ability for women to self-collect HPV samples can help reduce the number of health facility visits and improve cervical cancer screening coverage rates. Methods: We conducted a facility- and community-based cross-sectional study among 350 women aged 25–55 years in Arumeru di

Gut microbiome markers in subgroups of HLA class II genotyped infants signal future celiac disease in the general population : ABIS study

Although gut microbiome dysbiosis has been illustrated in celiac disease (CD), there are disagreements about what constitutes these microbial signatures and the timeline by which they precede diagnosis is largely unknown. The study of high-genetic-risk patients or those already with CD limits our knowledge of dysbiosis that may occur early in life in a generalized population. To explore early gut

The underlying mechanisms of sports injuries in Paralympic Goalball – a mixed-method study

Objective Data from the Paralympic Games indicate a fluctuating injury incidence in the Paralympic sport Goalball, but the mechanisms behind have not been explored. The aims of this study were to; i) quantitatively analyze Goalball injuries reported in the London 2012 and Rio 2016 Paralympic Games, ii) qualitatively explain the differences between both Games, and iii) qualitatively assess general