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Beskattning av pokervinster efter Grebbestadsdomen
Beskattning av pokervinster har inte minst under 2011 varit ett ämne för många diskussioner i media. Vissa anser att det krävs stora inslag av skicklighet för att vara duktig på poker och att det inte borde anses vara ett lotteri. Denna skicklighetsaspekt var fall för prövning i HD under 2011 i den s.k. Grebbestadsdomen. Vissa ansåg att domen skulle direkt avgöra om pokervinster skulle komma att bTaxation on poker winnings have not the least in 2011 been a topic of discussion in the media. Some believe that it requires significant element of skill to be good at poker and that it should not be considered a lottery. This skill aspect was tried in the Supreme Court in 2011 in the so-called Grebbestad verdict. Some felt that the appeal would directly determine whether poker profits would be ta
Effect of vitamin E on autolysis and sporulation of Aspergillus nidulans
Relative pollen productivity estimates in the forest steppe landscape of southeastern Romania
Antibiotic Prophylaxis With Trimethoprim/Sulfamethoxazole Instead of Cloxacillin/Cefotaxime Increases Inguinal Surgical Site Infection Rate After Lower Extremity Revascularization
Due to the consistently high proportion of surgical site infections (SSI) after vascular surgery, a change of prophylactic antibiotic therapy from cloxacillin/cefotaxime to trimethoprim/sulfamethoxazole (TMP-SMX) was conducted in 2016. The study included consecutive patients undergoing lower extremity revascularization due to acute or chronic lower extremity arterial disease. The antibiotic regime
The cysteine 34 residue of A1M/α1-microglobulin is essential for protection of irradiated cell cultures and reduction of carbonyl groups.
Liver and gallbladder cancer in immigrants to Sweden.
BACKGROUND: The changes of cancer incidence upon immigration can be used as an estimator of environmental influence on cancer risk. We studied site-specific liver and biliary cancers in first-generation immigrants to Sweden with an aim to search for aetiological clues and to find evidence for indigenous incidence rates. MATERIAL AND METHODS: We used the nation-wide Swedish Family-Cancer Database t
Targeting p53 in Vivo: A First-in-Human Study With p53-Targeting Compound APR-246 in Refractory Hematologic Malignancies and Prostate Cancer.
PURPOSEAPR-246 (PRIMA-1MET) is a novel drug that restores transcriptional activity of unfolded wild-type or mutant p53. The main aims of this first-in-human trial were to determine maximum-tolerated dose (MTD), safety, dose-limiting toxicities (DLTs), and pharmacokinetics (PK) of APR-246. PATIENTS AND METHODSAPR-246 was administered as a 2-hour intravenous infusion once per day for 4 consecutive d
Porcine embryonic brain cell cytotoxicity mediated by human natural killer cells
Intracerebral transplantation of porcine embryonic dopamine-producing neurons has been suggested as a method to treat patients with Parkinson's disease. Even though the brain is an immunologically privileged site, neuronal xenografts are usually rejected within a few weeks. T cells are important for this process, but the exact cellular events leading to rejection are poorly characterized. Brain ce
Identification of functional synonymous variants in familial breast cancer
The genetic causes of familial breast cancer are still unclear, where only less than 20% have evident germline mutations. Most studies focus on mutations that cause a direct impact in the protein, disregarding the synonymous variants, where the codon is changed but the amino acid encoded remains the same. Synonymous variants can affect mRNA stability and translation, by differences in codon usage
Randomized Trial of Very Early Medication Abortion
Background Medication abortion, with a combination of mifepristone and misoprostol, is highly effective and safe. However, there is insufficient evidence on efficacy and safety at very early gestations before a pregnancy can be visualized with ultrasonography. Methods We conducted a multicenter, noninferiority, randomized, controlled trial involving women requesting medication abortion at up to 42
Heteroplasmy of mutant mitochondrial DNA A10398G and analysis of its prognostic value in non-small cell lung cancer
Mitochondrial dysfunction is associated with pathogenic mitochondrial (mt)DNA mutations. The majority of mtDNA point mutations have a heteroplasmic status, which is defined as the coexistence of wild-type and mutated DNA within a cell or tissue. Previous findings demonstrated that certain mtDNA heteroplasmic mutations contribute to widely spread chronic diseases, including cancer, and alterations
Coffee intake and the vasopressin system : an epidemiological and experimental study
Coffee is epidemiologically linked to health benefits and risks. Coffee is thought to be a diuretic. However, it can still contribute to daily fluid intake. Vasopressin is the most important physiological regulator of body fluid balance and diuresis. This study aimed to map the effects of coffee intake on vasopressin concentration. In the population-based cross-sectional Malmö Offspring Study (n =
Sasi02 schedule
Microsoft Word - SASI02_schedule SASI02, Fall 2016 Sustainability studies: concepts, challenges and approaches (SASI02) Schedule Overview Day Date Time Venue Title Teacher Week 1 Mon 5/9 10‐12 * Introduction to the course Ideas, concepts Ellinor Isgren Wed 7/9 13‐15 * History of Environmental and Sustainability Studies Ellinor Isgren Week 2 Mon 12/9 1
https://www.lumes.lu.se/sites/lumes.lu.se/files/sasi02_schedule.pdf - 2026-06-04
CMES SEMINAR PROGRAM
Risk of Major Bleeding in Patients With Atrial Fibrillation Taking Dronedarone in Combination With a Direct Acting Oral Anticoagulant (From a U.S. Claims Database)
Dronedarone may increase exposure and the risk of major bleeding when prescribed with a direct oral anticoagulant (DOAC). This retrospective cohort study examined the risk of the first occurrence of major bleeding (hospitalization or emergency room visit for gastrointestinal [GI] bleeding, intracranial hemorrhage [ICH], or bleeding at other sites) among new users of apixaban, dabigatran, and rivar
Adult-onset inflammatory bowel disease and rate of serious infections compared to the general population : a nationwide register-based cohort study 2002–2017
Objectives: To investigate absolute and relative risk of serious infections in adult/elderly inflammatory bowel disease (IBD) diagnosed 2002–2017. Methods: Nationwide, register-based cohort study of Swedish patients with IBD compared with general population matched reference individuals with regard to time to first serious infection, equal to hospital admission. Multivariable Cox regression estima
Neonatal BCG vaccination and child survival in TB-exposed and TB-unexposed children : A prospective cohort study
Objectives To assess the association between neonatal BCG vaccination and mortality between 28 days and 3 years of age among tuberculosis (TB)-exposed and TB-unexposed children. Design Prospective cohort study. Setting Bandim Health Project runs an urban Health and Demographic Surveillance site in Guinea-Bissau with registration of mortality, vaccination status and TB cases. Participants Children
What Is the Structure of the E4 Intermediate in Nitrogenase?
Nitrogenase is the only enzyme that can cleave the strong triple bond inN2. The active site contains a complicated MoFe7S9C cluster. It is believed that itneeds to accept four protons and electrons, forming the E4 state, before it can bind N2.However, there is no consensus on the atomic structure of the E4 state. Experimentalstudies indicate that it should contain two hydride ions bridging two pai
A Nested Case–Control Study on the Risk of Surgical Site Infection After Thyroid Surgery
Introduction: It is unclear if antibiotic prophylaxis reduces the risk of surgical site infection (SSI) in thyroid surgery. This study assessed risk factors for SSI and antibiotic prophylaxis in subgroups of patients. Method and design: A nested case–control study on patients registered in the Swedish National Register for Endocrine Surgery was performed. Patients with SSI were matched 1:1 by age
