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Kursrapport mven21 ht 2018

MVEN21 2018 Kursansvarig: Åsa Håkansson, Institutionen för Livsmedelsteknik, LTH 1 Kursrapport MVEN21 HT 2018 Antal studenter: 14 Betyg: 7 st G, 7 st VG Utvärdering Sammanfattning Majoriteten av studenterna (medelvärde 4,3) är mycket nöjda med kursen och de anser att kursen är relevant för deras utbildning (medelvärde 4,6). Studenterna anser vidare att kursens mål, såsom de beskrivs i kursplanen,

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/kursrapport_mven21_ht_2018.pdf - 2026-06-04

Calendar & Events

Past BIOECONOMY events2019Katapult Summer School – in collaboration with Climate-KICThe programme consists of three thematic research groups that participate in a two-week residential programme to co-create and develop skills aiming for turning research into practice and develop solutions to tackle climate change. Professionals collaborate in two European cities. The BIOECONOMY graduate research s

https://www.cec.lu.se/education/postgraduate-studies/bioeconomy/calendar - 2026-06-03

Three genes expressing Kunitz domains in the epididymis are related to genes of WFDC-type protease inhibitors and semen coagulum proteins in spite of lacking similarity between their protein products

Background: We have previously identified a locus on human chromosome 20q13.1, encompassing related genes of postulated WFDC-type protease inhibitors and semen coagulum proteins. Three of the genes with WFDC motif also coded for the Kunitz-type protease inhibitor motif. In this report, we have reinvestigated the locus for homologous genes encoding Kunitz motif only. The identified genes have been

Antibiotic Prophylaxis With Trimethoprim/Sulfamethoxazole Instead of Cloxacillin/Cefotaxime Increases Inguinal Surgical Site Infection Rate After Lower Extremity Revascularization

Due to the consistently high proportion of surgical site infections (SSI) after vascular surgery, a change of prophylactic antibiotic therapy from cloxacillin/cefotaxime to trimethoprim/sulfamethoxazole (TMP-SMX) was conducted in 2016. The study included consecutive patients undergoing lower extremity revascularization due to acute or chronic lower extremity arterial disease. The antibiotic regime

Liver and gallbladder cancer in immigrants to Sweden.

BACKGROUND: The changes of cancer incidence upon immigration can be used as an estimator of environmental influence on cancer risk. We studied site-specific liver and biliary cancers in first-generation immigrants to Sweden with an aim to search for aetiological clues and to find evidence for indigenous incidence rates. MATERIAL AND METHODS: We used the nation-wide Swedish Family-Cancer Database t

Targeting p53 in Vivo: A First-in-Human Study With p53-Targeting Compound APR-246 in Refractory Hematologic Malignancies and Prostate Cancer.

PURPOSEAPR-246 (PRIMA-1MET) is a novel drug that restores transcriptional activity of unfolded wild-type or mutant p53. The main aims of this first-in-human trial were to determine maximum-tolerated dose (MTD), safety, dose-limiting toxicities (DLTs), and pharmacokinetics (PK) of APR-246. PATIENTS AND METHODSAPR-246 was administered as a 2-hour intravenous infusion once per day for 4 consecutive d

Porcine embryonic brain cell cytotoxicity mediated by human natural killer cells

Intracerebral transplantation of porcine embryonic dopamine-producing neurons has been suggested as a method to treat patients with Parkinson's disease. Even though the brain is an immunologically privileged site, neuronal xenografts are usually rejected within a few weeks. T cells are important for this process, but the exact cellular events leading to rejection are poorly characterized. Brain ce

Identification of functional synonymous variants in familial breast cancer

The genetic causes of familial breast cancer are still unclear, where only less than 20% have evident germline mutations. Most studies focus on mutations that cause a direct impact in the protein, disregarding the synonymous variants, where the codon is changed but the amino acid encoded remains the same. Synonymous variants can affect mRNA stability and translation, by differences in codon usage

Randomized Trial of Very Early Medication Abortion

Background Medication abortion, with a combination of mifepristone and misoprostol, is highly effective and safe. However, there is insufficient evidence on efficacy and safety at very early gestations before a pregnancy can be visualized with ultrasonography. Methods We conducted a multicenter, noninferiority, randomized, controlled trial involving women requesting medication abortion at up to 42

Heteroplasmy of mutant mitochondrial DNA A10398G and analysis of its prognostic value in non-small cell lung cancer

Mitochondrial dysfunction is associated with pathogenic mitochondrial (mt)DNA mutations. The majority of mtDNA point mutations have a heteroplasmic status, which is defined as the coexistence of wild-type and mutated DNA within a cell or tissue. Previous findings demonstrated that certain mtDNA heteroplasmic mutations contribute to widely spread chronic diseases, including cancer, and alterations

Coffee intake and the vasopressin system : an epidemiological and experimental study

Coffee is epidemiologically linked to health benefits and risks. Coffee is thought to be a diuretic. However, it can still contribute to daily fluid intake. Vasopressin is the most important physiological regulator of body fluid balance and diuresis. This study aimed to map the effects of coffee intake on vasopressin concentration. In the population-based cross-sectional Malmö Offspring Study (n =

Hekm22 schedule 20022018

HEKM22 Draft Schedule _07022018 Spring 2018, HEKM22 7,5 credits 1 Depar tment of Human Geography Human E co logy D i v i s ion HEKM22 Methods in Human Ecology Schedule Week Date Time Room Activity Topic Teacher 12 INTRODUCTION: 21/03 13-15 Malmö Lecture Introduction to the course and thinking about methods in research VR 23/03 10-12 Rio Lecture Overview of how to carry out interviews VR 13 INTERVI

https://www.keg.lu.se/sites/keg.lu.se/files/hekm22_schedule_20022018.pdf - 2026-06-04

Risk of Major Bleeding in Patients With Atrial Fibrillation Taking Dronedarone in Combination With a Direct Acting Oral Anticoagulant (From a U.S. Claims Database)

Dronedarone may increase exposure and the risk of major bleeding when prescribed with a direct oral anticoagulant (DOAC). This retrospective cohort study examined the risk of the first occurrence of major bleeding (hospitalization or emergency room visit for gastrointestinal [GI] bleeding, intracranial hemorrhage [ICH], or bleeding at other sites) among new users of apixaban, dabigatran, and rivar

Adult-onset inflammatory bowel disease and rate of serious infections compared to the general population : a nationwide register-based cohort study 2002–2017

Objectives: To investigate absolute and relative risk of serious infections in adult/elderly inflammatory bowel disease (IBD) diagnosed 2002–2017. Methods: Nationwide, register-based cohort study of Swedish patients with IBD compared with general population matched reference individuals with regard to time to first serious infection, equal to hospital admission. Multivariable Cox regression estima

Neonatal BCG vaccination and child survival in TB-exposed and TB-unexposed children : A prospective cohort study

Objectives To assess the association between neonatal BCG vaccination and mortality between 28 days and 3 years of age among tuberculosis (TB)-exposed and TB-unexposed children. Design Prospective cohort study. Setting Bandim Health Project runs an urban Health and Demographic Surveillance site in Guinea-Bissau with registration of mortality, vaccination status and TB cases. Participants Children

What Is the Structure of the E4 Intermediate in Nitrogenase?

Nitrogenase is the only enzyme that can cleave the strong triple bond inN2. The active site contains a complicated MoFe7S9C cluster. It is believed that itneeds to accept four protons and electrons, forming the E4 state, before it can bind N2.However, there is no consensus on the atomic structure of the E4 state. Experimentalstudies indicate that it should contain two hydride ions bridging two pai