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Arms Trade, Human Rights and the Jurisdictional Threshold: On the Responsibility of Arms Transferring States Under the European Convention on Human Rights

Under vapenhandelsfördraget och rådets gemensamma ståndpunkt 2008/944/GUSP av den 8 december 2008 om fastställande av gemensamma regler för kontrollen av export av militär teknik och krigsmateriel (EU:s gemensamma ståndpunkt) är stater skyldiga att minimera de humanitära konsekvenserna av internationell export och överföring av vapen. Vapenhandel är alltjämt en växande industri. En allt större andThe Arms Trade Treaty (ATT) as well as Council Common Position 2008/944/CFSP of 8 December 2008 defining common rules governing control of exports of military technology and equipment (EU Common Position) impose substantive obligations on states for the purpose of minimising the adverse humanitarian effects of global arms trade. Notwithstanding these commitments, arms trade is an expanding busines

Den suveräna statens skyldighet att skydda miljön

Den här uppsatsen utforskar möjligheten till miljömässigt motiverad intervention (vilket i uppsatsen är definierat som ekologisk intervention), med syfte att tvinga upphörande av annan stats miljöförstöring med global påverkan, och hur en sådan lösning skulle påverka det internationella klimatet politiskt och juridiskt. Uppsatsen utgår ifrån de bakomliggande miljörättsliga och folkrättsliga princi

The "Formgivning" of Domus, Kristianstad

Today, we are creating and building more than ever. While buildings rise from the horizon, the consumption of building materials increases massively. More than 22% of global carbon dioxide emissions come from the consumption of building materials such as concrete, steel, and aluminum, etc. 55% of embodied carbon in a conventional building is in the structure and substructure (Smedley, 2019). Hence

Ändring av talan i ljuset av rättskraften - En undersökning av rättskraftens utveckling och innebörd för 13 kap. 3 § RB

Flera olika synsätt på rättskraftens omfattning har genom historien presenterats. Traditionellt sett har ett samband mellan rättskraften i 17 kap. 11 § Rättegångsbalken (RB) och 13 kap. 3 § st. 3 RB, taleändringsregeln, utpekats. Genom Högsta domstolens avgöranden har rättskraften utvidgats och rättsläget börjat klarna. Denna uppsats syftar till att dels undersöka rättskraftens omfattning närmre, Several different opinions on the scope of res judicata have been presented throughout history. Traditionally a connection between res judicata in chapter 17, article 11 of the Swedish Code of Judicial Procedure (RB) and the rule of amendment in chapter 13, article 3, paragraph 3 RB has been pointed out. Through the rulings of the Supreme Court the scope of res judicata has been expanded and its d

Det som krävs för att Lunds Klimatallians ska kunna utveckla sina medlemmars hållbarhetsarbete

Lunds Klimatallians har ambitioner att hjälpa sina medlemmar arbeta mot en hållbar utveckling och letar efter nya metoder för att förbättra sin insats. Lunds Klimatallians är en organisation som startades i initiativ av Lund Kommuns miljöstrategiska enhet i syfte att bidra till Sveriges genomförande av FN:s klimatmål. Målen ska leda världen mot en hållbar utveckling men i dagsläget finns hållbarheLund's Climate Alliance was initiated 2010 by the municipality of Lund, in southern Sweden, to support local climate adaptation and mitigation efforts. The purpose of this paper is to investigate what each member of Lund's Climate Alliance believes will be necessary to realize sustainability goals particular to their organization in the future. The study thereby points to new topics, activ

Mild versus moderate stages of Alzheimer's disease: three-year outcomes in a routine clinical setting of cholinesterase inhibitor therapy.

BACKGROUND: There is an increasing interest in cognitive and functional outcomes in the respective stages of Alzheimer's disease (AD) and in novel therapies particularly for the milder phases of AD. Our aim was to describe and compare various aspects of disease progression in patients with mild versus moderate AD in routine clinical practice of cholinesterase inhibitor (ChEI) therapy. METHODS: Thi

Efficient Arsenic Metabolism - The AS3MT Haplotype Is Associated with DNA Methylation and Expression of Multiple Genes Around AS3MT.

Arsenic is a very potent toxicant. One major susceptibility factor for arsenic-related toxicity is the efficiency of arsenic metabolism. The efficiency, in turn, is associated with non-coding single nucleotide polymorphisms (SNPs) in the arsenic methyltransferase AS3MT on chromosome 10q24. However, the mechanism of action for these SNPs is not yet clarified. Here, we assessed the influence of gene

Long-term outcomes five years after selective dorsal rhizotomy

Background: Selective dorsal rhizotomy (SDR) is a well accepted neurosurgical procedure performed for the relief of spasticity interfering with motor function in children with spastic cerebral palsy (CP). The goal is to improve function, but long-term outcome studies are rare. The aims of this study were to evaluate long-term functional outcomes, safety and side effects during five postoperative y

Variant ABO Blood Group Alleles, Secretor Status, and Risk of Pancreatic Cancer: Results from the Pancreatic Cancer Cohort Consortium

Background: Subjects with non-O ABO blood group alleles have increased risk of pancreatic cancer. Glycosyltransferase activity is greater for the A(1) versus A(2) variant, whereas O01 and O02 variants are nonfunctioning. We hypothesized: 1) A(1) allele would confer greater risk than A(2) allele, 2) protective effect of the O allele would be equivalent for O01 and O02 variants, 3) secretor phenotyp

Tea Consumption and Incidence of Type 2 Diabetes in Europe: The EPIC-InterAct Case-Cohort Study

Background: In previous meta-analyses, tea consumption has been associated with lower incidence of type 2 diabetes. It is unclear, however, if tea is associated inversely over the entire range of intake. Therefore, we investigated the association between tea consumption and incidence of type 2 diabetes in a European population. Methodology/Principal Findings: The EPIC-InterAct case-cohort study wa

Current smoking status is a strong predictor of radiographic progression in early rheumatoid arthritis: results from the SWEFOT trial

Objectives To study clinical predictors for radiographic progression after 1 year in an early rheumatoid arthritis (RA) trial. Methods In the SWEFOT trial population, disease modifying antirheumatic drug (DMARD) naive RA patients started methotrexate; 3-month responders (DAS28 <3.2) continued (n=147), while non-responders were randomised to addition of sulfasalazine +hydroxychloroquine (n=130) or

Individually tailored treatment with epirubicin and paclitaxel with or without capecitabine as first-line chemotherapy in metastatic breast cancer: a randomized multicenter trial

Anthracyclines and taxanes are active cytotoxic drugs in the treatment of early metastatic breast cancer. It is yet unclear whether addition of capecitabine to the combination of these drugs improves the treatment outcome. Patients with advanced breast cancer were randomized to first-line chemotherapy with a combination of epirubicin (Farmorubicin(A (R))) and paclitaxel (Taxol(A (R))) alone (ET) o

Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls

Introduction: Synaptic dysfunction and degeneration are central events in Alzheimer's disease (AD) pathophysiology that are thought to occur early in disease progression. Synaptic pathology may be studied by examining protein biomarkers specific for different synaptic elements. We recently showed that the dendritic protein neurogranin (Ng), including the endogenous Ng peptide 48 to 76 (Ng(48-76)),

Cangrelor During Percutaneous Coronary Intervention in Patients With Cardiogenic Shock or Cardiac Arrest

Background: Little is known regarding treatment with cangrelor during percutaneous coronary intervention (PCI) in patients with myocardial infarction complicated by cardiogenic shock or cardiac arrest. Objectives: The aim of this study was to investigate the effects of such cangrelor treatment during PCI in patients with myocardial infarction complicated by cardiogenic shock or cardiac arrest. Met

Cardiac rehabilitation and physical activity decrease the risk of stroke after acute myocardial infarction : A nationwide cohort study in Sweden

Background: Stroke and acute myocardial infarction (AMI) rank among the leading causes of mortality. Physical activity and exercise are recommended as part of rehabilitation after AMI to prevent cardiovascular events, but the importance for stroke prevention has not been investigated using population-based data. Objectives: To determine associations between participation in exercise-based cardiac

High-Resolution 3D Turbo Spin-Echo Wrist MRI at 7T Accelerated by Compressed Sensing

This study aimed to obtain high-resolution 3D isotropic turbo spin-echo (TSE) wrist MRI acquisitions at 7T, with and without fat suppression, facilitated by compressed-sensing (CS) acceleration. In 16 healthy subjects, fat-suppressed (FS) and nonfat-suppressed (NFS) TSE wrist images were obtained. The protocol consisted of a SENSE-accelerated scan, with an isotropic voxel size of 0.45 mm and acqui

Bimodal solutions in peritoneal dialysis : what can we expect from different glucose volumes added to the icodextrin bag? Data from a simulation procedure

Background: Ultrafiltration (UF) insufficiency in peritoneal dialysis (PD) often leads to transfer to hemodialysis. Therefore, strategies to prolong time on therapy are needed. The use of a combined crystalloid and colloid solution, also called bimodal PD, can help improve UF. Methods: We propose a method for reconstituting bimodal solutions. Three bimodal PD solutions, with respectively 100 ml (s

Kan en heterosexuell man ha feministiskt sex? En studie av villkoren för mänskligt handlande.

Sammanfattning Syftet med denna uppsats är att söka svar på vilka analytiska verktyg som krävs för att förstå villkoren för mänskligt handlande. Min tes är att den diskursteoretiska epistemologi som kommit att dominera samtida feministisk forskning - i uppsatsen representerad främst av Judith Butler - inte tillhandahåller dessa analytiska verktyg. För att pröva denna tes har jag intervjuat fem he

En utgående modell? - en diskussion kring grunderna för rättsligt föräldraskap och vårdnadsansvar

Uppsatsen handlar om grunderna för rättsligt föräldraskap, konstruktionen av dess rättsverkningar i allmänhet och vårdnadsansvaret i synnerhet samt denna konstruktions kompatibilitet med familjer som inte faller in under begreppet kärnfamilj. Den deskriptiva delen av uppsatsen innehåller ett inledande resonemang kring begreppen förälder och vårdnad, en genomgång av rättsläget rörande fastställande