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BACKGROUND: Low level of physical activity is a risk factor for new cardiac events in out-of-hospital cardiac arrest (OHCA) survivors. Physical activity can be assessed by self-reporting or objectively by accelerometery.AIM: To investigate the agreement between self-reported and objectively assessed physical activity among OHCA survivors HYPOTHESIS: Self-reported levels of physical activity will s

Background: Studies show that early, integrated palliative care (PC) improves quality of life (QoL) and end-of-life (EoL) care for patients with poor-prognosis cancers. However, the optimal strategy for delivering PC for those with advanced cancers who have longer disease trajectories, such as metastatic breast cancer (MBC), remains unknown. We tested the effect of a PC intervention on the documen

Avhandlingen är en studie av hur stöd och service organiseras kring fyra barn med funktionshinder och deras familjer. I denna service är normalt flera olika formella organisationer involverade, som barnhabilitering, förskola/skola/särskola, hjälpmedelscentral, assistentorganisationer, sjukvård m fl. Dessutom kan barnets och familjens situation vara komplicerad på många sätt. Själva funktionshindreThis study explores the organising of services for disabled children and their families in Sweden. It is based on 83 interviews with parents and involved staff surrounding four disabled children, with both physical and intellectual disabilities, and between two and nine years old. Further, 15 meetings between parents and staff were observed, primarily serving as background material. The service pr

Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an emerging and potentially life-saving procedure, necessitating qualified operators in an increasing number of centres. The procedure shares technical elements with other vascular access procedures using the Seldinger technique, which is mastered by doctors not only in endovascular specialties but also in trauma surg

Objective: Antimicrobial resistance is a growing worldwide problem and is considered to be one of the biggest threats to global health by the World Health Organization. Insights into the determinants of antibiotic prescribing may be gained by comparing the antibiotic usage patterns of Australia and Sweden. Design: Publicly available data on dispensed use of antibiotics in Australia and Sweden betw

Background and aim: Patient activation (PA) and Patient Involvement (PI) are considered elements in good survivorship. We aimed to evaluate the effect of a follow-up supported by electronic patient-reported outcomes (ePRO) on PA and PI. Method: From February 2017 to January 2019, we conducted an explorative interventional study. We included 187 patients followed after intended curative complex sur

BackgroundHypoplastic left heart syndrome is associated with significant morbidity and mortality. We aimed to assess the influence of left ventricular morphology and choice of shunt on adverse outcome in patients with hypoplastic left heart syndrome and stage 1 palliation.Methods and ResultsThis was a retrospective analysis of patients with hypoplastic left heart syndrome with stage 1 palliation b

INTRODUCTION: Patients with clinically node-negative breast cancer have a negative sentinel lymph node status (pN0) in approximately 75% of cases and the necessity of routine surgical nodal staging by sentinel lymph node biopsy (SLNB) has been questioned. Previous prediction models for pN0 have included postoperative variables, thus defeating their purpose to spare patients non-beneficial axillary

BACKGROUND: Accumulating studies reported that several phosphodiesterases (PDEs) inhibitors might have cardiovascular benefits.OBJECTIVES: This study aimed to explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian randomization (MR) approach, and then examine the effect of inhibitors of identified target on the outcomes by using real-world

Background and purpose: Tamoxifen remains an important adjuvant treatment in premenopausal patients with hormone receptor-positive breast cancer. Thus, determination of hormone receptors is important. Here, we compare cytosol-based methods, immunohistochemistry (IHC), and gene expression (GEX) analysis for determining hormone receptor status in premenopausal breast cancer patients from a randomise

I syfte att bekämpa grov brottslighet vidtar svenska myndigheter olika provokativa åtgärder, däribland brottsprovokation. Otillbörlig brottsprovokation innebär att någon provoceras att begå ett brott som denne annars inte hade begått. Detta är idag otillåtet, både enligt svensk rätt och enligt Europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande fri- och rättigheterIn order to combat serious crime, Swedish authorities implement provocative actions, including entrapment. Undue entrapment means that someone is provoked to commit a crime that he or she would not otherwise have committed. This is currently prohibited, both under Swedish law and under the European Convention on Human Rights (ECHR). The purpose of the prohibition of such entrapment is to protect t

This thesis presents an in-depth investigation into the behaviour of two distinct industrial material systems under specialized conditions: diamond tools machining titanium alloys and the annealing of alumina-forming steels. The observation of two sub-projects was finished by two state-of-the-art synchrotron facilities FlexPES and MAXPEEM respectively at the MAX IV laboratory. The study elucidates

The objective of this work was to develop a harmonised Life-Cycle Assessment methodology tailored specifically for assessing the environmental impact of daylighting systems. These systems include various architectural features, such as windows, skylights, or shading devices, designed to optimize the use of daylight in a space. This project aligns with the efforts to unify LCA practices within the

Utgångspunkten i en totalentreprenad är att beställaren i förfrågningsunderlaget ska föreskriva ett funktionskrav, vilket entreprenören genom projekterade tekniska lösningar ska förverkliga. Inte sällan innehåller dock beställarens förfrågningsunderlag mer långtgående krav i form av egna tekniska lösningar eller detaljer för en sådan teknisk lösning. Detta innebär att beställaren redan har utfört The starting point in a design-build contract is that the client must prescribe a functional requirement in the tender documents, which the contractor must realize through designed technical solutions. However, it is not uncommon for the client's tender documents to contain more far-reaching requirements in the form of their own technical solutions or details of such a technical solution. This

Sedan införandet av EU:s GMO‑lagstiftning år 2001 har användningen av nya genomiska tekniker (NGT) inom genmodifiering av växter ökat markant inom EU. NGT:er skiljer sig från vedertagna genomiska tekniker genom att de utför mer precisa förändringar i en organisms genom. Uppsatsens fokus ligger på växter som framställts med NGT:erna riktad mutagenes, cisgenes och intragenes. Cisgenes och intragenesSince the introduction of the GMO-legislation in 2001, the EU has seen an increased use of new genomic techniques (NGTs) in the field of plant gene modification. NGTs differ from established genomic techniques by performing more precise changes in an organism’s genome. The thesis focuses on plants produced with the NGTs targeted mutagenesis, cisgenesis and intragenesis. Cisgenesis and intragenesis

Produktion av en nanotrådssolcell För att ta itu med miljöpåverkan från växthusgaser krävs en övergång till förnyelsebara energikällor. Ett exempel på en sådan källa är nanotrådssolceller. I mitt examensarbete har jag undersökt hur nanotrådar kan arrangeras på sådant sätt som krävs för att kunna omvandla solljuset till elektricitet. Global uppvärmning är ett hot som till stor del orsakas av utslThe demand for cheaper and more efficient solar cells is high. One way to decrease cost of material, while maintaining a high degree of efficiency, is to take advantage of nanomaterials. A thin film containing pn-junction nanowires can convert light with an efficiency comparable to traditional planar cells, while using a fraction of the material, and thus reduce costs. At the company Sol Voltaics

Populärvetenskaplig sammanfattning: Är klimatforskningen skev? En central fråga är om vi kan lita på att vetenskapliga tidskrifter återger en rättvis bild av aktuella forskningsresultat? Dessutom bör vi fråga oss hur rapporteringen påverkas då betydande händelser sker inom vetenskapsvärlden. I november 2007 och senare 2009 skedde två viktiga företeelser inom klimatforskningen som potentiellt kanAbstract The declaration of a scientific consensus concerning anthropogenic causes for climate change by the IPCC in their fourth assessment report (AR4), published in 2007, initiated a heated debate. During this debate, experts within the IPCC were accused of selective reporting and the AR4 got strong source criticism by politicians, stakeholders and climate skeptics in general. The debate furth

Sedan våren 2014 har delar av Ukrainas östra territorium kontrollerats av separatister som understödjs av Ryssland. Separatisterna har utropat nya folkrepubliker, som dock inte erkänts som nya stater av det internationella samfundet. På grund av separatisternas territoriella kontroll kan Ukraina inte säkerställa att Europakonventionen om de mänskliga rättigheterna efterlevs och respekteras i regioWhen Ukraine lost control over parts of its eastern territory to separatists in 2014, it indicated that it no longer had the ability to fulfil its obligations under the European Convention of Human Rights in regards to that area. However, although the separatists have proclaimed their own states, these are not recognised by the international community. Since the ECHR only applies to state parties

Ett nytt sätt att lägga upp försvar i våldtäktsmål har dykt upp i svenska domstolar de senaste åren. Detta försvar rör invändningen om sexsomni, det vill säga att den tilltalade skulle ha utfört den sexuella handlingen i sömnen. Denna uppsats syftar till att undersöka hur invändningen hanteras rättsligt. Vidare är det att reflektera över om det finns andra lösningar, då den rättsliga hanteringen iA new defence against rape has appeared in Swedish courts in the last couple of years. This defence is based on the objection of sexsomnia, which means that the accused has performed the sexual act while asleep. This thesis aims to investigate how the objection is handled legally. Furthermore, the purpose is to analyse whether there are other solutions, since the judicial handling of sexsomnia in