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European Spallation Source Lattice Design Status

The accelerator of the European Spallation Source (ESS) will deliver 62.5 mA proton beam of 2.0 GeV onto the target, offering an unprecedented beam power of 5 MW. Since the technical design report (TDR) was published in 2013, work has continued to further optimise the accelerator design. We report on the advancements in lattice design optimisations after the TDR to improve performance and flexibil

The Membrane-Spanning Domain of Complex I Investigated with Fusion Protein Techniques

Popular Abstract in Swedish När vi äter kolhydrater, fett, protein och andra näringsämnen sker kemiska reaktioner i kroppen som kan liknas vid dom som sker när man eldar en brasa. Vid förbränning reagerar kolhydrater med syre och bildar koldioxid och vatten. Denna förbränning frigör den energi som funnits lagrad i kolhydraterna, i brasan i form av värme, och i kroppens celler omvandlas den till keNADH:quinone oxidoreductase, or complex I, is a large, complex and poorly understood bioenergetic enzyme in the respiratory chain of living organisms. The enzyme has a conserved core structure, comprising fourteen protein subunits: Seven subunits protrude from the membrane and contain a flavin prosthetic group and eight iron-sulfur clusters that guide electrons from the oxidation of NADH towards t

Stable isotopes reveal differences in diet among reed bunting subspecies that vary in bill size

Reed bunting Emberiza schoeniclus subspecies vary considerably in bill size and shape and seem to be at an early stage of speciation, in which bill might be indirectly causing reproductive isolation. Hence, we evaluated whether bill size, as well as age and sex, are associated with foraging niche in three west European subspecies of reed bunting: the thin-billed schoeniclus, the intermediate-bille

Ghrelin affects gastrectomy-induced decrease in UCP1 and beta(3)-AR mRNA expression in mice.

this study we investigated the effects of gastrectomy (Gx) and of the gastric hormone, ghrelin, on the expression of proteins in brown adipose tissue (BAT) that are thought to be involved in thermogenesis. Heat production in BAT is known to depend upon activation and increased expression of β3-adrenergic receptors (β3-AR) and the consequent up-regulation of uncoupling protein 1 (UCP1). Mice were s

Femtosecond charge transfer in assemblies of discotic liquid crystals

The electronic coupling strength within columns of discotic liquid crystals is investigated using core-level Coexisting well-ordered and disordered regions are identified in thin films of tetra-alkoxy-substituted phthalocyanines with the aid of near edge X-ray absorption fine structure and photoelectron spectroscopies. These different regions Lire used to derive a lower limit for the intermolecula

Location of interstitial cells and neurotransmitters in the mouse bladder

To investigate whether interstitial cells (ICs) are present in the adult mouse bladder, and what transmitters characterize adjacent nerve fibres, as ICs in human and guinea-pig bladder lie close to nerve fibres but transmitters present in these nerves have not yet been reported. Sections of the bladder wall from 12 adult male mice (six each, aged 3-4 or 18-24 months) were incubated in carboxygenat

Asymmetric interaction specificity between two sympatric termites and their fungal symbionts

1. Fungus-growing termites live in an obligate mutualistic symbiosis with Termitomyces fungi. The functions of the fungal symbiont have been hypothesised to differ between species and to range from highly specific roles of providing plantdegrading enzymes complementary to termite gut enzymes, to non-specific roles of providing protein-rich food to the termites. 2. Termite species with unspecialise

In vitro effect of fibrinogen on Candida albicans germ tube formation

Pseudohyphae formation by Candida albicans blastoconidia, as seen in vaginal smears, is a phenotypical change commonly assumed to mean fungal invasiveness, i.e. not mere colonization. C. albicans forms germ tubes in vitro in the presence of serum. In our search for inhibitory components of germ tube formation, we decided to study fibrinogen. The inhibition of germ tube formation by clinical isolat

Molecular alignment of ammonia studied by electron-ion-ion coincidence spectroscopy

Electron-ion-ion coincidence measurements carried out at discrete resonances near the N 1s threshold in ammonia are reported. The measured coincidence spectra show clear alignment of the molecule upon resonant core-electron excitation. The coincidence data are analyzed to extract information about the molecule in the excited state by simulating the alignment and the dissociation processes. Dynamic

311881 Lokalförsörjningsplan 2022

Lokalförsörjningsplan 2022 Lokalförsörjningsplan 2022 LUNDS UNIVERSITET FÖRORD .................................................................................... 5 1. LOKALFÖRSÖRJNING VID LUNDS UNIVERSITET ................6 1.1 Mål för Lunds universitets campus och lokaler ................ 7 1.2 Campusutveckling .......................................................... 8 1.3 Principer för lokal

https://www.staff.lu.se/sites/staff.lu.se/files/2022-05/311881_Lokalf%C3%B6rs%C3%B6rjningsplan%202022%20.pdf - 2026-05-07

Quantitative proteomic analysis reveals metabolic alterations, calcium dysregulation and increased expression of extracellular matrix proteins in laminin α2 chain-deficient muscle.

Congenital muscular dystrophy with laminin α2 chain-deficiency (MDC1A) is one of the most severe forms of muscular disease and is characterized by severe muscle weakness and delayed motor milestones. The genetic basis of MDC1A is well-known, yet the secondary mechanisms ultimately leading to muscle degeneration and subsequent connective tissue infiltration are not fully understood. In order to obt

Social Economy as Antidote to Criminal Economy: How Social Cooperation is Reclaiming Commons in the Context of Campania’s Environmental Conflicts

This article contributes to ongoing debates on how bottom-up social cooperation can halt and reverse processes of environmental and human degradation, dispossession and impoverishment, by proposing a synchronization of resistance and of commoning practices. The article moves from the empirical case of social and ecological conflicts currently unfolding in the so-called Land of Fires, an area in So

Exciton dynamics in alternating polyfluorene/fullerene blends

Exciton dynamics in alternating copolymer/fullerene solar cell blends have been investigated using femtosecond transient absorption spectroscopy. The acceptor concentrations have been varied over a wide range. Experimental data, kinetic modeling and simulations, all indicate that the efficiency of exciton conversion to charges is 100% even at acceptor concentrations as low as 20 wt%. The reported

Intermolecular exciton-exciton annihilation in phospholipid vesicles doped with [Ru(bpy)(2)dppz](2+)

The ultrafast photophysics of [Ru(bpy)(2)dppz](2+) (dppz = dipyrido[3,2-a:2',3'-c]-phenazine) embedded into the walls of phospholipid vesicles has been studied by femtosecond time-resolved pump-probe spectroscopy. While [Ru(bpy)(2)dppz](2+) has been studied intensively with respect to its intramolecular charge transfer processes, which are associated with the well known light-switch effect, this s

Sampling and Characterization of Sub-Micrometer High-Temperature Particles Present in the Product Gas from a Circulating Fluidized-Bed Biomass Gasifier

The removal of particulate fine fractions by a proper high-temperature cleaning device is a very important issue in the development of the biorefinery concept. Therefore, in this investigation, particles from a 100 kW(th) steam-O-2 blown circulating fluidized-bed (CFB) gasifier were sampled and characterized. The sampling was performed with a specially designed heated dilution probe downstream of

Carbon nanorings: A challenge to theoretical chemistry

High-level quantum-chemical methods show that the binding in the inclusion complex of hexamethylbenzene (HMB) in 6-cycloparaphenitacetylene (6-CPPA) cannot be explained only in terms of electrostatic interactions-caused by the polarization associated to curved a-conjugated systems-and the inclusion of dispersion forces is definitely needed. The theoretical description of van der Wools interactions