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The effect of different glutamate‐receptor antagonists on the induction of cortical spreading depression of Leao and of cortical anoxic membrane depolarization were investigated in the anaesthetized rat. Spreading depression (SD), elicited by mechanical stimulation of the cortical surface, was inhibited by the non‐competitive N‐methyl‐d‐aspartate (NMDA)‐receptor blocker, (±)‐5‐methyl‐10,11‐dihydro

Acute myeloid leukemia (AML) with t(9;22)(q34;q11), also known as AML with BCR-ABL1, is a rare, provisional entity in the WHO 2016 classification and is considered a high-risk disease according to the European LeukemiaNet 2017 risk stratification. We here present a retrospective, population-based study of this disease entity from the Swedish Acute Leukemia Registry. By strict clinical inclusion cr

Lactobacillus reuteri metabolises glycerol efficiently to form 3-hydroxypropionic acid (3-HP) and 1,3-propanediol (1,3PDO) by the same mechanism as that for 1,2-propanediol (1,2PDO) conversion to propionic acid and propanol via its propanediol utilization (pdu) pathway. Pdu enzymes are encoded by the pdu-operon, which also contain genes encoding the shell proteins of the microcompartment housing t

Background: A novel potential approach for lung transplantation could be to utilize xenogeneic decellularized pig lung scaffolds that are recellularized with human lung cells. However, pig tissues express several immunogenic proteins, notably galactosylated cell surface glycoproteins resulting from alpha 1,3 galactosyltransferase (α-gal) activity, that could conceivably prevent effective use. Use

Bonäsheden, Sweden's largest continuous dune field, situated in the county of Dalarna, central Sweden, has been investigated using LiDAR (light detection and ranging) remote sensing, ground penetrating radar as well as by field observations and luminescence dating. The use of LiDAR in conjunction with geographic information system (GIS) software proved to be efficient in mapping the inactive dune

The present article analyses the relation between politics and historiography in communist Romania (1948- 1989). Since the beginning of the four-decades-long communist dictatorship, history has been turned into an ancillary discipline of the political discourse. The analysis of this peculiar kind of historiography starts from the processes that have determined its political nature and brought to i

Background: Around 70% of all ICU patients are treated with antibiotics whereas up to 30% are suggested as unnecessary. Measuring antibiotic consumption is a prerequisite to improving its use and the purpose of the present investigation was to explore the use of antibiotics in Swedish ICUs. Material and methods: Daily Defined Doses (DDDs) of antimicrobials delivered to Swedish ICUs, 2016–2018, wer

BACKGROUND AND OBJECTIVES: Under the ISBT, the Working Party (WP) for Red Cell Immunogenetics and Blood Group Terminology is charged with ratifying blood group systems, antigens and alleles. This report presents the outcomes from four WP business meetings, one located in Basel in 2019 and three held as virtual meetings during the COVID-19 pandemic in 2020 and 2021.MATERIALS AND METHODS: As in prev

Engineered and devitalized hypertrophic cartilage (HC) has been proposed as bone substitute material, potentially combining the features of osteoinductivity, resistance to hypoxia, capacity to attract blood vessels, and customization potential for specific indications. However, in comparison with vital tissues, devitalized HC grafts have reduced efficiency of bone formation and longer remodeling t

The purpose of this thesis was to explore the sustainability of a renewable village grid micro hydropower project in the Murung Raya district of Central Kalimantan Province, Indonesia, according to indicators for five dimensions of sustainability: economic, environmental, social, technical, and institutional. The theoretical discussion and subsequent analytical framework are rooted in dimensions o

This paper discusses the potential economic consequences of the countervailing duty imposed on solar panels imported from China by the EU. The paper is motivated by recent studies that indicate potential future costs from a world energy market that is characterized by technics that give rise to high relative levels of carbon dioxide. The intention is to discuss the potential effect that countervai

One of the most debated political events during 2016 was the referendum regarding the United Kingdom’s future in the European Union. Despite the many warnings received from economists the UK voters voted for ‘leave’, paving the way for Brexit. This thesis reviews some possible alternatives regarding the UK-EU relationship post Brexit and concludes that the economically best case scenario would be

Prebiotics are non-digestible carbohydrates that selectively stimulate the growth and activity of health promoting bacteria in the colon, resulting in homeostasis to the gut environment. It is considered to be the solution of many health-related diseases such as type-2 diabetes, cardiovascular disease and cancer. Arabinoxylooligosaccharides, the hydrolysis product of arabinoxylan from plant cell w

Den som mottagit en förmånersättning enligt SFB kan bli återbetalningsskyldig om det visar sig att utbetalningen varit felaktig. Även om den felaktiga ersättningen inte orsakats av den försäkrade själv kan det bedömas att det skäligen borde ha funnits en insikt om att utbetalningen varit felaktig. När det finns en god man eller förvaltare förordnad för den försäkrade uppstår en oklarhet i vems insOne who has received a benefit payment under socialförsäkringsbalken may be liable to repay if it turns out that the payment was erroneous. Even if the erroneous payment was not caused by the insured, it may be judged that there should have been a realization that the payment was erroneous. When there is a trustee or administrator acting for the insured, there is a lack of clarity in whose realiza

En grundläggande princip inom konkursrätten är att konkursboet inte ansvarar för gäldenärens tidigare förpliktelser. Miljörätten däremot är uppbyggd runt syftet att kunna utkräva ansvar från en stor krets av fysiska och juridiska personer, detta i syfte att skydda nuvarande och kommande generationer. Det problematiska är att kombinera dessa två lagstiftningar och syften. Syftet för den här framsA fundamental principle within the bankruptcy law is that the bankruptcy estate is not responsible for the debtor’s prior obligations. The environmental law is built around the purpose of enabling the enforcement system to demand accountability from a large group of corporations and persons. This, for the purpose of protecting present and future generations. An important matter is how to combine t