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In this analytical chapter we focus on human factors to shed light on what a 21st-century project might look like from within. Adopting a non-essentialist perspective to project-making, we at the same time acknowledge that the notion of human nature is blurred, dynamic, changeable, heterogeneous, and internally riven. The human condition, hence, always dictates what ontological position a project
Popular Abstract in Swedish Avhandlingen Optimization of Low-Level Controllers and High-Level Polymer Grade Changes är inom ämnesområdet reglerteknik. Det centrala i ämnet reglerteknik är att styra ett system, såsom en motor, ett teleskop eller en kemisk reaktor, så att det uppför sig på ett önskvärt sätt. Detta görs genom att använda mätningar av systemet, en algoritm som beräknar hur systemet sTwo design problems at different levels in the control hierarchy are considered; optimization of robust low-level controllers with constrained control signal activity and optimization of economical high-level polyethylene grade changes. As for the first design problem, a constraint on control signal activity due to measurement noise is presented and used when optimizing and comparing PI/PID contr
Background: In egg-laying animals, mothers can influence the developmental environment and thus the phenotype of their offspring by secreting various substances into the egg yolk. In birds, recent studies have demonstrated that different yolk substances can interactively affect offspring phenotype, but the implications of such effects for offspring fitness and phenotype in natural populations have
Att investera sina pengar på ett smart sätt – så kallad portföljoptimering – är en grundläg- gande utmaning inom finans. Traditionellt har detta byggt på att man försöker förutspå framtida avkastning och hur olika tillgångar samvarierar. Men dessa uppskattningar är ofta osäkra och kan leda till felbeslut. I takt med att maskininlärning blivit allt vanligare inom finansvärlden har nya metoder utvecPortfolio optimization is a central problem in finance, with traditional approaches of- ten relying on forecasts of expected returns and covariances. With the growing adoption of machine learning in finance, return forecasting using ML techniques has become in- creasingly common. More recently, an alternative approach has been proposed where the portfolio weights are learned directly, bypassing th
Kan proteiner visa vägen till bättre plaståtervinning och en renare värld? Vissa typer av proteiner(enzymer) har under de senaste åren visat prov på nedbrytning av plast och kan därför bli en ny och hållbar metod för plaståtervinning. Mest framgångsrikt är en typ av enzymer som kallas cutinas som kan effektivt bryta ner PET, som bland annat finns i PET-flaskor. Nu visar forskning på att användninPolyolefins make up the majority of all plastics produced and can be found in a range of applications. Simultaneously, 60% of all plastics are not being recycled, and consequently are accumulating in the environment where it poses serious threats to both the environment, human health, and economies. Current attempts to address the problem have had limited success. An emerging solution is biodegrad
The aim of this thesis is to investigate how queer students in Danish upper-secondary schools expe- rience and navigate their school environments and how this is influenced by institutional practices. As such, this thesis adopts a dual perspective on queer students by investigating experiences of and agency within school environments, in the form of how they choose to respond to situations of dis-
The Foreign Subsidies Regulation (FSR) came into effect in July 2023, with the aim of addressing foreign subsidies which potentially lead to distortions in the internal market of the European Union (EU). Since the Commission published its proposal for the Regulation, the FSR has come under consistent scrutiny from both scholars and stakeholders. In particular, scholars have noted the lack of clari
‘’Brandscapes: Rethinking fashion retail spaces in a digital age’’ explores the evolving role of branded environments in response to ongoing digital and economic shifts. As online platforms and e-commerce reshape consumer behavior, physical retail spaces face challenges justifying their presence and redefining their relevance. Rather than viewing these environments as solely transactional, this th
Sexualbrott mot barn utgör en särskilt komplex kategori av brottmål där be-visningen ofta i huvudsak består av barnets utsaga. För att skydda barnet från ytterligare psykisk påfrestning härs barnet i regel inte muntligen inför rätten, utan utsagan förebringas genom videoförhör från förundersökningen. Denna ordning innebär avsteg från principerna om muntlighet och omedelbarhet vilka normalt utgör cSexual offences against children constitute a particularly complex category of criminal cases, in which the evidence often consists primarily of the child´s statement. In order to protect the child from further psychological strain, the child is generally not heard orally before the court. Instead, the statement is presented through video-recorded interviews from the preliminary investigat-ion. Th
Exaggerated neutrophil activation and formation of neutrophil extracellular traps (NETs) are reported in systemic sclerosis (SSc) but its involvement in SSc pathogenesis is not clear. In the present study we assessed markers of neutrophil activation and NET formation in SSc patients in relation to markers of inflammation and disease phenotype. Factors promoting neutrophil activation in SSc remain
Background and Objectives: The International Society of Blood Transfusion (ISBT) Working Party (WP) on Red Cell Immunogenetics and Blood Group Terminology (RCI&BGT) held six business meetings between December 2021 and June 2024. This report describes the new blood group systems and antigens ratified during these meetings. Materials and Methods: Candidate systems and antigens were reviewed acco
Den pågående energiomställningen har inneburit en överhalning av både policy och infrastruktur. Medan beslutsfattare och industrin letar efter nya tillvägagångssätt för att tackla alltmer växande problem som klimatomställningar, resiliens och energifattigdom, är sektorn under total transformation. Det finns en ökad medvetenhet om att energisektorn inte bara består av teknik, utan också av människoDen pågående energiomställningen har inneburit en överhalning av både policy och infrastruktur. Medan beslutsfattare och industrin letar efter nya tillvägagångssätt för att tackla alltmer växande problem som klimatomställningar, resiliens och energifattigdom, är sektorn under total transformation. Det finns en ökad medvetenhet om att energisektorn inte bara består av teknik, utan också av människo
The drafters of the 1990 Dublin Convention knowingly and willfully disregarded divergences among Member States' protection systems. Like a boomerang, the fallacy of this approach has now reappeared in cases where asylum seekers have challenged transfers under the Convention, tasking judges to tackle a problem which its drafters avoided. The core issue of this article is whether and when such diver
Objectives: The paper describes recruitment results and characteristics of the UP-TECH clinical trial sample, including level of care services use, informal caregiver burden and its determinants.Methods: UP-TECH is designed to test innovative care solutions for community-dwelling patients with moderate stage Alzheimer's disease and their caregivers in Italy. Four hundred and fifty patient-caregive
One of the conclusions from comparative empirical studies of the structural challenges towards making global production and consumption patterns compatible with environmental limits is that rich countries would need to ‘degrow’ (O’Neill 2015; Fritz and Koch 2016). To shed light on the potential role of the state in such a planned downscaling process the paper compares state roles in a capitalist e
The transformation of chronic lymphocytic leukemia (CLL) to high-grade B-cell lymphoma is known as Richter's Syndrome (RS) and it is a rare event with dismal prognosis. In this study, we conducted whole genome sequencing (WGS) of paired circulating CLL (PB-CLL) and RS biopsies (tissue-RS) from 17 clinical trial (CHOP-O) patients. We found that tissue-RS was enriched for mutations in poor-risk CLL
