Sorting and processing of neutrophil granule proteins
Popular Abstract in Swedish Sortering av bakteriedödande proteiner till behållarna i vita blodkroppar Vita blodkroppar har en livsviktig roll i det medfödda immunförsvaret som fagocyter, bakterieätare. Denna funktion, första linjens försvar, utövas av neutrofila granulocyter (neutrofiler), en speciell slags vita blodkroppar som är specialiserade på bakterieätning (fagocytos). När bakterier angripThe neutrophil granulocytes have a critical role in innate immunity in particular through phagocytosis of microorganisms. Their cytoplasmic granule subsets store digestive enzymes and antibiotic proteins that are released during this event. During the passage in the secretory pathway the granule proteins are retrieved from constitutive secretion to become sorted for storage. The aim of this thesis
