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Increased pulmonary blood volume variation in patients with heart failure compared to healthy controls; a non-invasive, quantitative measure of heart failure

Variation of the blood content of the pulmonary vascular bed during a heartbeat can be quantified by pulmonary blood volume variation (PBVV) using magnetic resonance imaging (MRI). The aim was to evaluate if PBVV differs in patients with heart failure compared to healthy controls and investigate the mechanisms behind the PBVV. Forty-six patients and 10 controls underwent MRI. PBVV was calculated f

A new perspective in the road asset management with the use of advanced monitoring system & BIM

The present paper reports different applications which have a common data source: Automatic Road Analyzer (ARAN) of the Transport Infrastructure Laboratory of the University of Catania. Data surveyed with ARAN were used to develop performance indicators of the road asset. A BIM model makes possible to improve the flexibility in information access and to merge data with the aim to allow a complete

Proteomic profiling of osteoarthritis. A computational approach to biomarker discovery.

Understanding the molecular mechanisms of osteoarthritis (OA) is critical for early diagnosis and effective treatment. OA is a leading cause of disability and poses an increasing burden on healthcare systems, particularly with an aging global population. Despite the potential of proteomics to elucidate the complex biology underlying OA, its application remains limited due to challenges including g

Metabolic engineering of Thermoanaerobacterium AK17 for increased ethanol production in seaweed hydrolysate

Sustainably produced renewable biomass has the potential to replace fossil-based feedstocks, for generation of biobased fuels and chemicals of industrial interest, in biorefineries. In this context, seaweeds contain a large fraction of carbohydrates that are a promising source for enzymatic and/or microbial biorefinery conversions. The thermoanaerobe Thermoanaerobacterium AK17 is a versatile ferme

Quantification of heat shock proteins in the posterior interosseous nerve among subjects with type 1 and type 2 diabetes compared to healthy controls

Introduction: Diabetic peripheral neuropathy (DPN) is a common complication of both type 1 (T1D) and type 2 diabetes (T2D). No cure for DPN is available, but several potential targets have been proposed for treatment. Heat shock proteins (HSPs) are known to respond to both hyper- and hypoglycemia. DPN can be diagnosed using electrophysiology and studied using peripheral nerve biopsies.Aim: This st

Exposure to polystyrene nanoplastics reduces bacterial and fungal biomass in microfabricated soil models

Nanoplastics have been proven to induce toxicity in diverse organisms, yet their effect on soil microbes like bacteria and fungi remains largely unexplored. In this paper, we used micro-engineered soil models to investigate the effect of polystyrene (PS) nanospheres on Pseudomonas putida and Coprinopsis cinerea. Specifically, we explored the effects of increasing concentrations of 60 nm carboxylat

Three perspectives on learning in a simulated patient scenario : a qualitative interview study with student, simulated patient, and teacher

INTRODUCTION: Patient simulation can be useful for medical students in developing communication skills for vulnerable situations. Three participants are primarily involved in the patient simulation activities: the student, the simulated patient (SP), and the teacher. We here aimed to explore these participants' perceptions of learning in a patient simulation scenario.METHODS: We conducted individu

Habitat complexity affects microbial growth in fractal maze

The great variety of earth's microorganisms and their functions are attributed to the heterogeneity of their habitats, but our understanding of the impact of this heterogeneity on microbes is limited at the microscale. In this study, we tested how a gradient of spatial habitat complexity in the form of fractal mazes influenced the growth, substrate degradation, and interactions of the bacterial st

On the convergence rate of the dirichlet-neumann iteration for coupled poisson problems on unstructured grids

We consider thermal fluid structure interaction with a partitioned approach, where typically, a finite volume and a finite element code would be coupled. As a model problem, we consider two coupled Poisson problems with heat conductivities $$\lambda _1$$, $$\lambda _2$$ in one dimension on intervals of length $$l:1$$ and $$l:2$$. Hereby, we consider linear discretizations on arbitrary meshes, such

Growth patterns and their contributing factors among HIV-exposed uninfected infants

With expanded HIV treatment and prevention programmes, most infants born to HIV-positive women are uninfected, but the patterns and determinants of their growth are not well described. This study aimed to assess growth patterns in a cohort of HIV-exposed uninfected (HEU) infants who participated in an experimental HIV vaccine trial and to test for associations with maternal and infant factors, inc

Frame disputes or frame consensus? "environment" or "welfare" first amongst climate strike protesters

Present debates suppose a close linkage between economic, social, and environmental sustainability and suggest that individual wellbeing and living standards need to be understood as directly linked to environmental concerns. Because social movements are often seen as an avant-garde in pushing for change, this article analyzes climate protesters' support for three key frames in current periods of

A reduced-order through-flow program for choked and cooled axial turbines

A reduced-order through-flow program has been developed at the Lund Institute of Technology. The goal of the work was to develop and verify a program suitable for scientific studies of coaxial turbines. The program has built-in capability for multiple choked stages, and turbine cooling, as well as flexible modules for state, losses, deviation, and blockage. The code uses Matlab [trademark] as a pl

Copyright Protection of Software under the TRIPS Agreement - Software reengineering and reverse engineering in the context of international trade law

In 1994, the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) was adopted as part of the Agreement Establishing the World Trade Organization (WTO). Pursuant to the TRIPS Agreement copyright protection of computer programs for the first time had received explicit recognition on the international level. Despite obligating all WTO Members to protect computer programs as lite

Auschwitz, autenticitet, kunskap

This essay reflects on issues surrounding the remembrance and teaching of the Holocaust. It was commissioned by the project Living History and the Swedish Prime Minister's Office.