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Antibiotika-resistens utgör ett ökande hälsoproblem i världen och bakterier blir alltmer resistenta mot de antibiotika vi har att behandla med. Fler bakterier blir också resistenta mot mer än ett antibiotikum och behandling av infektioner med dessa typer av bakterier kompliceras av bristen på effektiva läkemedel vilket leder till ökade sjukvårdskostnader, längre vårdtider och en minskad chans att Multi-drug resistant (MDR) infections remain the leading cause of death worldwide. MDR infections caused by Streptococcus pneumoniae (Spn), Streptococcus pyogenes (GAS) and Streptococcus agalactiae (GBS) are considered global threats to human health due to increased spread of antibiotic resistance and limited treatment options. In this thesis, we present the human milk derived HAMLET (Human Alpha-

The raison d’être of the humanities is widely held to reside in its unique ability to generate critical thinking and critical thinkers. But what is “critical thinking?” Is it a generalized mode of reasoning or a form of political critique? How does it relate to discipline-specific practices of scholarly pursuit? How does it relate to discourses of “post-truth” and “alternative facts”? How is it be

 While greater incentives and new funding models for antibiotic drug develooment are needed, it is unclear whether a system dependent on endlessly churning out new and ever more expensive medicines will be  economically feasible and scientifically possible in the long term. Greater priority should therefore be given to implementing more permanent solutions that are not limited to slowing resistanc

Demarketing is generally recognized as that aspect of marketing that aims at discouraging customers in general or a certain class of customers in particular on either a temporary or permanent basis and has been increasingly posited as a potential tool to degrow tourism and improve its overall sustainability, particularly as a result of so-called overtourism. The paper provides an overview of the v

Previous studies have shown that measurements of beluga whale (Delphinapterus leucas) and bottlenose dolphin (Tur-siops truncatus) echolocation signals at off-axis angles may be well modeled using a Gaussian bell function or a chirped Gaussian function as envelope. In this paper, we apply a novel technique, the matched window reassignment, for investigation of a range of models of dolphin echoloca

Digital twins, which are a new concept in industrial control systems (ICS), play a key role in realizing the vision of a smart factory, and they can have different effective use cases. With digital twins, we have virtual replicas of physical systems so that they precisely mirror the internal behavior of the physical systems. Hence, synchronization is necessary to keep the states of digital twins i

This paper presents an evaluation of single input single output (SISO), single input multiple output (SIMO) and multiple input multiple output (MIMO) channel capacities for a dual antenna prototype in proximity of a user. The dual antenna prototype mimics today’s small mobile phone design in size and in comprising internal, compact, multi-band antennas. Four different user cases are evaluated by m

We consider a system where a number of independent, time-triggered or event-triggered control loops are closed over a shared communication network. Each plant is described by a first-order linear stochastic system. In the event-triggered case, a sensor at each plant frequently samples the output but attempts to communicate only when the magnitude of the output is above a threshold. Once access to

Benchmarking has received much attention in local government. However, since benchmarking within a networking environment is quite a recent phenomenon, there is a need for better understanding of the impact of these networks on local government. This article describes municipal benchmarking networks and analyzes and categorizes variations in action and performance among municipalities participatin

In this paper, standard-cell based memories (SCMs)are proposed as an alternative to full-custom sub-VT SRAM macros for ultra-low-power systems requiring small memory blocks. The energy per memory access as well as the maximum achievable throughput in the sub-VT domain of various SCM architectures are evaluated by means of a gate-level sub-VT characterization model, building on data extracted from

When globular proteins fold into their characteristic three-dimensional structures, some amino acids are located on the surface, while others are situated in the protein core, where they cannot interact with molecules in the environment. Predicting the degree of solubility of amino acids provides insight into the function and relevance of residues. Residue accessibility is crucial for several prot

High-resolution phase-contrast 3D imaging using nano-holotomography typically requires collecting multiple tomograms at varying sample-to-detector distances, usually 3 to 4. This multi-distance approach limits temporal resolution, making it impractical for operando studies. Moreover, shifting the sample complicates reconstruction, requiring precise alignment, registration, and interpolation to cor

The Open and Reproducible Musculoskeletal Imaging Research community is a scientific community dedicated to promoting openness and reproducibility in musculoskeletal imaging, image processing, and computational modeling. In this perspective paper, we outline the motivations for conducting transparent research and provide practical guidelines for implementing it. We start by defining open and repro

Craft is re-emerging in debates on improving contemporary work. A recurring theme in research on craft is its potential to thwart alienation, which is considered one of the central pathologies of modern work. Through a case study of the Swedish craft beer community, we examine craft’s potential for de-alienating work. Drawing on Jaeggi’s conception of alienation as a relation of relationlessness,