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Research on violence on digital platforms have focused on how perpetrators exploit ano-nymity, Geo-tracking, blackmail and other tools to abuse a victim online and very little re-search has been done in regards on how society and organisations protect the victims. This thesis explores what organisations that work with domestic violence victims experience when it comes to digital technology. Four u
Directional crack growth criteria in compressed elastic–plastic materials are considered. The conditions at the crack tip are evaluated for a straight stationary crack. Remote load is a combined hydrostatic stress and pure shear, applied via a boundary layer assuming small scale yielding. Strains and deformations are assumed to be small. Different candidates for crack path criteria are examined. M
Under de senaste 100 åren har vi successivt minskat vår dagliga fysiska aktivitet. Eftersom vi är mindre vältränade, svagare och mer överviktiga har benägenheten att drabbas av sjukdomar som diabetes och hjärt- och kärlsjukdomar ökat. WHO rapporterar att 25% av vuxna inte uppfyller de globala rekommenderade nivåerna av fysisk aktivitet. Vår forskningsenhet är intresserad av att lära sig hur genetiDuring the last 100 years, we have gradually reduced our daily physical activity. As less fit, weaker, and fatter, we have become more prone to diseases like diabetes and cardiovascular disease. The WHO reports that one in four adults do not meet the global recommended levels of physical activity. Our research unit is interested in learning how genetic variation influences skeletal muscle function
Lungcancer är en vanlig tumörsjukdom med dåliga behandlingsresultat och den cancerform som skördar flest liv i Sverige och globalt. Rökning är den starkaste riskfaktorn för lungcancer men 10-15% av patienterna har aldrig rökt. Lungcancer är en heterogen sjukdom på molekylär nivå. För att förbättra diagnostiken, behandlingen och prognosen i lungcancer behövs en bättre förståelse av tumörspecifika fLung cancer, the leading cause of cancer death, is divided into histological subtypes with large differences in molecular alterations, clinical presentation, and patient outcome. By a combined clinical and molecular approach we focus on improving the molecular understanding of lung cancer and translate research findings into a clinical diagnostics. By characterization of the genomic, transcriptio
Epidemiology is the study of the distribution of diseases and disease promoting factors in the population. The cardiovascular epidemiology research group focuses on studies of cerebrovascular diseases (stroke) and heart diseases, such as myocardial infarction, heart failure or atrial fibrillation. The research is performed in well characterized population-based cohorts, with extensive information
We aim to identify novel interventions for prevention and treatment of diabetes-related cardiovascular disease (CVD). Our strategy is to identify genetic, endocrine and metabolic disturbances in humans which are causally related to disease development and are detectable many years before disease presents. We then test in both animals and in human intervention studies if manipulation of such molecu
Avdelningen forsknings- och externkommunikation har följande ansvarsområden: forskningskommunikation, innehållsproduktion, samt redaktion och medierelationer.The Research and External Communication unit has the following areas of responsibility: research communication, content production, editorial activities and media relations.
Ferric uptake regulator (Fur) and Fur-like proteins form an important family of transcriptional regulators in many bacterial species. In this work we have characterized a Fur-like protein, the peroxide regulator PerR, in an M1 serotype of Streptococcus pyogenes. To determine the role of PerR in S. pyogenes, we inactivated the gene by allelic replacement. PerR-deficient bacteria showed 48% reductio
