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Older patients with acute myeloid leukemia benefit from intensive chemotherapy: an update from the Swedish acute leukemia registry.
Most patients with acute myeloid leukemia (AML) are older, the median age is 71 years, and survival decreases rapidly with age. The achievement of complete remission and long-term survival mostly require intensive combination chemotherapy, but standard regimens are often believed to be too toxic for older patients. The Swedish Acute Leukemia Registry is unique and contains data on 98% of all patie
Co-benefits from sustainable dietary shifts for population and environmental health : an assessment from a large European cohort study
Possible benefits from a knowledge management system - Attitudes towards the use of a knowledge management approach at a small department
Assets of today’s organizations consist part in the form of immaterial assets. These immaterial assets often have the form of employees and their knowledge, which put a demand on effective means of communicating and organizing knowledge within an organization. To capture, facilitate, store, and communicate knowledge, several types of systems can be used. We have done an inductive case study of a s
ErbB2 status and the benefit from two or five years of adjuvant tamoxifen in postmenopausal early stage breast cancer
AIM: We aimed to study the importance of erbB2 status in early stage postmenopausal breast cancer for patients who participated in a trial of five vs. two years of adjuvant tamoxifen.PATIENTS AND METHODS: We analysed the erbB2 status of the tumours from 577 patients participating in the trial, either by a DNA amplification assay (n = 181) or by measurement of the protein level with flow cytometry
Children’s routes to participation in support groups: motives, barriers, and benefits from children’s and parent’s perspectives
I Sverige erbjuds förebyggande stödgrupper av socialtjänsten för barn som växer upp i familjer där det förekommer våld, missbruk eller psykisk ohälsa. Stigma som är kopplad till föräldrars problem och till socialtjänstens inblandning utgör hinder för barns deltagande i stödgrupper. I denna artikel undersöks barns och föräldrars upplevda motiv, hinder och fördelar med deltagandet genom att utforskaIn Sweden, preventive support groups for children exposed to domestic violence, substance abuse, or mental illness in the home are provided by local child welfare services. The stigma associated with parental problems and the involvement of child welfare services are barriers to children’s participation in support groups. This article examines the motives, barriers, and benefits according to child
Illegality and inequity in Ghana's cocoa-forest landscape : How formalization can undermine farmers control and benefits from trees on their farms
Schemes to promote sustainable forest management have increasingly focused on addressing widespread informalities in timber production, based on the presumed links between formalisation, the maintenance of forest cover and local welfare. This trend is typified by the EU Forest Law Enforcement, Governance and Trade (FLEGT) initiative and associated Voluntary Partnership Agreements (VPA) aimed at er
Can costs of pesticide exposure for bumblebees be balanced by benefits from a mass-flowering crop?
Mass-flowering crops provide forage for bees but also contain pesticides. Such pesticide exposure can harm bees, but our understanding of how this cost is balanced by forage benefits is limited. To provide insights into benefits and costs, we placed bumblebee colonies in 18 landscapes with conventional red clover fields treated with the neonicotinoid thiacloprid (flowers + pesticide), untreated or
The OA Trial Bank: meta-analysis of individual patient data from knee and hip osteoarthritis trials show that patients with severe pain exhibit greater benefit from intra-articular glucocorticoids.
To evaluate the efficacy of intra-articular (IA) glucocorticoids for knee or hip osteoarthritis (OA) in specific subgroups of patients with severe pain and inflammatory signs using individual patient data (IPD) from existing trials.
High-Risk Premenopausal Luminal A Breast Cancer Patients Derive no Benefit from Adjuvant Cyclophosphamide-based Chemotherapy: Results from the DBCG77B Clinical Trial
Response to Mortality Benefits From US Population-Wide Reduction in Sodium Consumption: Projections From 3 Modeling Approaches
Biogas from waste materials as transportation fuel – benefits from an environmental point of view.
The majority of people with type 1 diabetes and multiple daily insulin injections benefit from using continuous glucose monitoring : An analysis based on the GOLD randomized trial (GOLD-5)
Aim: To identify responders to continuous glucose monitoring (CGM) in relation to reductions in HbA1c and percentage of time spent in hypoglycaemia after initiation of CGM for individuals with type 1 diabetes treated with multiple daily insulin injections. Materials and Methods: We analysed data from 142 participants in the GOLD randomized clinical trial. We evaluated how many lowered their HbA1c
Patients Undergoing Breast-Conserving Surgery Can Benefit from the Opportunity to Participate in Choosing Their Surgical Technique
Background: Shared decision-making is increasingly advocated in many countries. The aims of this study were to investigate whether patients receiving breast-conserving surgery at Skåne University Hospital Malmö, Sweden, perceived an offered possibility to join in the decision-making process regarding the surgical method; to identify potential determinants for not having perceived such an offer; an
Benefiting from Spontaneously Generated 2D/3D Bulk-Heterojunctions in Ruddlesden−Popper Perovskite b
The Euro and the Nation-State That Never Disappeared: Would Europe Benefit from the Return of National Currencies?
This chapter discusses the current problems and future prospects of the euro area. The author argues that the problem for the euro area is not the return of the nation-state, but that the nation-states never disappeared. A common currency requires common economic policies, which is largely lacking in the euro area. As a result, large economic and social imbalances have emerged. The chapter examine
Benefit from extended surveillance interval on colorectal cancer risk in Lynch syndrome
Wild-goose chase, no predictable patient subgroups who benefit from meniscal surgery : patient-reported outcomes of 641 patients 1 year after surgery
The Benefits from an Accessible Web: a Case Study
En explosiv ökning av interaktiva webbttjänster gör att webb-tillgänglighet är ett hett ämne. Det syftar på att alla, oavsett funktionsnedsättningar, ska komma åt webb-innehåll. Företag med hundratals applikationer kan genom förbättrad till- gänglighet e ektivisera arbetsprocesser, spara resurser och rekrytera er.There is an explosive growth in on-line information and interactive services provided on the Web. Web accessibility refers to designing these websites so that all people, no matter disabilities, can access Web content. Recently in Sweden, laws and regulations have been imposed, requiring private corporations to ensure an accessible digital work environment. Scania is a major Swedish automotive ind
Fungi benefit from two decades of increased nutrient availability in tundra heath soil.
If microbial degradation of carbon substrates in arctic soil is stimulated by climatic warming, this would be a significant positive feedback on global change. With data from a climate change experiment in Northern Sweden we show that warming and enhanced soil nutrient availability, which is a predicted long-term consequence of climatic warming and mimicked by fertilization, both increase soil mic