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This study estimated the risk of second primary malignancies after Hodgkin's lymphoma (HL) in relation to family history of cancer, age at diagnosis and latency, among 6946 patients treated for HL in Sweden in 1965-1995 identified through the Swedish Cancer Register (SCR). First-degree relatives (FDRs) to the HL patients and their malignancies were then ascertained together with their malignancies

The pathogenesis of ulcerative colitis (UC) remains unknown. It is thought to be due to an abnormal and uncontrolled immune response to normally occurring constituents of the intestine. Microbial agents appear to be involved in the pathogenesis and intestinal bacteria seem to be an important factor in the development and chronicity. The aim of this study was to investigate the colonic microbiota o

This Letter presents measurements of the differential cross-sections for inclusive electron and muon production in proton-proton collisions at a centre-of-mass energy of root s = 7 TeV, using data collected by the ATLAS detector at the LHC. The muon cross-section is measured as a function of p(T) in the range 4 < p(T) < 100 GeV and within pseudorapidity vertical bar eta vertical bar < 2.5. In addi

Several deep Greenland ice cores have been retrieved, however, capturing the Eemian period has been problematic due to stratigraphic disturbances in the ice. The new Greenland deep ice core from the NEEM site (77.45°N, 51.06°W, 2450 m.a.s.l) recovered a relatively complete Eemian record. Here we discuss the cosmogenic (10)Be isotope record from this core. The results show Eemian average (10)Be con

In addition to HLA, recent genome-wide association studies (GWASs) of Hodgkin's lymphoma (HL) have identified susceptibility loci for HL at 2p16.1, 8q24.21 and 10p14. In this study, we perform a GWAS meta-analysis with published GWAS (totalling 1,465 cases and 6,417 controls of European background), and follow-up the most significant association signals in 2,024 cases and 1,853 controls. A combine

The major intrinsic proteins (MIPs) form a large protein family of ancient origin and are found in bacteria, fungi, animals, and plants. MIPs act as channels in membranes to facilitate passive transport across the membrane. Some MIPs allow small polar molecules like glycerol or urea to pass through the membrane. However, the majority of MIPs are thought to be aquaporins (AQPs), i.e., they are spec

A method of growing high-quality epitaxial Ge layers on a Si(100) substrate is reported. In this method, a 0.8 mum Si0.1Ge0.9 layer was first grown. Due to the large lattice mismatch between this layer and the Si substrate, many dislocations form near the interface and in the lower part of the Si0.1Ge0.9 layer. A 0.8 mum Si0.05Ge0.95 layer and a 1.0 mum top Ge layer were subsequently grown on the

Post-consolidation immunotherapy with histamine dihydrochloride and interleukin-2 has been shown to improve leukemia-free survival in acute myeloid leukemia in a phase III trial. For this study, treatment efficacy was determined among 145 trial patients with morphological forms of acute myeloid leukemia as defined by the French-American-British classification. Leukemia-free survival was strongly i

We investigate the growth and the physical and optical properties of type-II heterostructured ZnTe/ZnSe colloidal nanocrystals, focusing on the role of the 7% lattice mismatch between the two materials in determining growth homogeneity and band structure. We find that the lattice mismatch between the two materials places limitations on the range of structures that can be grown, and for those in wh

The feasibility of digesting energy crops supplemented with macro- and micronutrients instead of manure, without the commonly applied long hydraulic retention time (HRT), was investigated in long-term, single-stage continuous stirred tank processes. The crops used were mixtures of sugar beets, maize and whole crop triticale. The organic loading rate (OLR) measured as a total solid (TS) was 1.5-5.5

We present an interactive, searchable expressed sequence tag database for the periwinkle snail Littorina saxatilis, an upcoming model species in evolutionary biology. The database is the result of a hybrid assembly between Sanger and 454 sequences, 1290 and 147 491 sequences respectively. Normalized and non-normalized cDNA was obtained from different ecotypes of L. saxatilis collected in the UK an

Nontypeable Haemophilus influenzae (NTHi) is one of the main aetiologies of childhood bacterial infections as well as exacerbations in COPD patients. Currently, no licensed NTHi vaccine exists. In the present study, we evaluated the potential of the conserved and ubiquitous surface protein Haemophilus Protein F (PF) as a vaccine candidate. Our results show that incubation of NTHi with anti-PF anti

To fulfill increasing requirements within the manufacturing sector, highly flexible and adaptable automation systems are needed. It is desirable to have one integrated approach that stretches from the process planning phase, through the implementation phase and all the way to the phase for execution of the process control logics. One promising approach is to use the concepts of service-oriented ar

Background: Development of multiple primary tumors is a hallmark of hereditary cancer. At least 1/10 of breast cancers and colorectal cancers occur because of heredity and recently the cell cycle kinase 2, CHEK2 1100delC allele has been identified at a particularly high frequency in families with hereditary breast and colorectal cancer. Methods: We utilized the Southern Sweden population-based can

The uterine arteries and arteries in the wall and core of myomas were examined with transvaginal color and spectral Doppler ultrasound in 28 premenopausal and 17 postmenopausal women with uterine myomas. Eighteen premenopausal women and 100 postmenopausal women without myomas served as the controls for uterine artery Doppler measurements. The respective median time-averaged maximum velocity and pu