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Background and purpose: During radiotherapy, rectal cancer patients show inter-fractional internal motion that effects the delivered dose distribution. The purpose of this work is to study I) the inter-fractional bladder volume change, II) the effect of bladder volume change on bowel dose distribution, III) the effect of bladder optimization on the relationship between bladder volume and bowel dos
Frågan om bevisning utgör en viktig fråga även i skiljeförfaranden. I synnerhet skriftlig bevisning är viktig då den överlag anses vara mer tillförlitlig än muntlig sådan. Det är därför av vikt att part får tillgång till all skriftlig bevisning, även sådan som motpart eller annan kan tänkas inneha. Om dessa dokument frivilligt företes av part eller tredje man uppstår inga problem. Problemen börjar
Chemical Loping Combustion (CLC) is a novel combustion technology in which the exhaust gas is inherently divided into oxygen depleted air in one stream and CO2 and water vapour in another. This is however under the ideal condition that the fuel conversion is complete, i.e. all the hydrocarbons in the fuel is transformed to heat, water vapour and CO2. The CO2 capture rate can under such ideal condi
The impact of cytogenetic findings in AML was analyzed in the large population-based Swedish AML registry. Karyotypic patterns differed by age: t(8;21), inv(16) and t(11q23) were more common in younger patients, whereas loss of 5q, 7q and 17p, monosomal karyotype (MK) and complex karyotype (CK) were more common in older patients. Patients with ≥5 chromosome abnormalities had worse overall survival
The thesis analyzes and explains the current situation for the Russian minority in Estonia. Using Oren Yiftachel’s theoretical framework of Ethnocracy, it examines key documents related to integration, such as the constitution and policy documents, through textual analysis. It briefly covers the integration process from independence in the 1990s to the present. The findings of the study shows that
This thesis examines legal tensions arising from the interaction between OECD/G20 IF Administrative Guidance and the Pillar Two Directive within the EU legal order. While the Pillar Two Directive remains locked into version of OECD/G20 IF Pillar Two rules as they stood in 2022, the OECD/G20 IF continues to develop its Pillar Two framework through subsequent Administrative Guidance. The thesis exam
Corporate misconduct is a persistent feature of contemporary organizational life, yet corporations rarely acknowledge wrongdoing when confronted with allegations of harm. Instead, they rely on discursive strategies that protect legitimacy, organizational identity, and moral credibility. This chapter examines how corporations employ techniques of neutralization to defend themselves against accusati
This study examines how customary and statutory land governance systems intersect in shaping land governance outcomes in post-conflict Liberia, with specific focus on Gbarnga City, Bong County. Despite the Land Rights Act of 2018 formally recognizing customary land ownership, significant gaps persist between legal provision and experienced tenure security, particularly for women and customary comm
Background: Mental health problems are prevalent among adolescents with severe obesity, but long-term mental health outcomes after adolescent bariatric surgery are not well known. We aimed to assess mental health outcomes over 5 years of follow-up after Roux-en-Y gastric bypass surgery in adolescents who participated in the Adolescent Morbid Obesity Surgery (AMOS) study. Methods: This was a non-ra
This study examined journalists' perceptions regarding the legal system's ability to protect them against online harassment. By utilizing open-ended survey responses from respondents with varying levels of trust in the legal system, the findings suggested a need for increased technical proficiency, resources, and priority within the legal system to adequately address the issue. Additionally, a rec
IMPORTANCE: The clinical utility of stress cardiovascular magnetic resonance imaging (CMR) in stable chest pain is still debated, and the low-risk period for adverse cardiovascular (CV) events after a negative test result is unknown.OBJECTIVE: To provide contemporary quantitative data synthesis of the diagnostic accuracy and prognostic value of stress CMR in stable chest pain.DATA SOURCES: PubMed
The Syrian civil war has been described as a first example of the conflicts expected in the wake of climate change. The conflict, which started in 2011, was preceded by a severe drought in 2007–2009 that hit agriculture and the rural population hard. But what do we really know about what happened to Syria’s climate and agriculture before and after the start of the conflict? In this article, I summ
Background: Exposure and Response Prevention (ERP) is a form of behavioural therapy for tics; however, its effectiveness remains uncertain. We aimed to evaluate the effectiveness of internet-delivered, therapist-supported, and parent-assisted ERP for treatment of tics in children and young people with Tourette syndrome or chronic tic disorder. Methods: This multicentre, parallel group, single-blin
Previous research has focused on how governments and public authorities can limit civil society organisations’ (CSOs) autonomy by shrinking their operational civic space and their democratic functions. There has been less attention paid to how other external actors and types of pressure might restrict access to civic space and how it can induce coping responses on both an individual and organizati
Importance: Long-term follow-up after transcatheter aortic valve replacement (TAVR) is of interest given that longitudinal data on mortality and durability of transcatheter heart valves are limited. The REPRISE III (Repositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus Valve System-Randomized Clinical Evaluation) randomized clinical trial compared the mecha
Background: Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often scarce. We aimed to determine whether thrombolytic treatment with intravenous tenecteplase given within 4·5 h of awakening improves functiona
We examine the causes and policy implications of strategic (willful) ignorance of risk as an excuse to overengage in risky health behavior. In an experiment on Copenhagen adults, we allow subjects to choose whether to learn the calorie content of a meal before consuming it, and measure their subsequent calorie intake. Consistent with previous studies, we find strong evidence of strategic ignoranceWe examine the causes and policy implications of strategic (willful) ignorance of risk as an excuse to over-engage in risky health behavior. In an experiment on Copenhagen adults, we allow subjects to choose whether to learn the calorie content of a meal before consuming it and then measure their subsequent calorie intake. Consistent with previous studies, we find strong evidence of strategic igno
Hjärtsvikt betecknar ett syndrom som innebär att hjärtat har otillräcklig förmåga att försörja kroppen med blod. Detta kan antingen bero på att hjärtat inte kan fyllas med eller stöta ut tillräckligt med mängd blod. Patienter med hjärtsvikt har i allmänhet hög dödlighet, detta trots att stora framsteg har gjorts avseende behandlingen av hjärtsvikt, speciellt sedan 1980-talet. Femårsöverlevnaden föIntroduction: Despite major advances, the incidence rate and mortality of heart failure (HF) remains high, with a five-year survival of approximately 50%. At the time of inception of this thesis the familial risks of HF, including the aspects of mortality, were largely underdetermined. This thesis is composed of four papers with the main aims as follows:To determine the risk of hospitalization of
Popular Abstract in Swedish Avhandlingen handlar om hur fett (lipider) i kosten bryts ner och transporteras i blodet för att slutligen antingen användas som energi, byggstenar i cellväggarna eller lagras i fettväven. I den här avhandlingen kan man också läsa om hur man kan modifiera fetter med hjälp av speciella proteiner: enzymer för att förbättra näringsinnehållet och dess fysikaliska egenskaperAn important indicator of the metabolic capacity of humans is the ability to regulate plasma triacylglycerol levels and to clear triacylglycerol-rich lipoproteins (TRLs) from the circulation after a meal. This is crucial since most of the day is spent in the postprandial state. High concentrations and long circulation times of TRL remnants may be detrimental since these are considered to be highly
