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Objectives: Long-term, placebo-controlled studies of cholinesterase inhibitors (ChEIs) in Alzheimer’s disease (AD) are not permitted for ethical reasons. Therefore, the advancement of knowledge on longitudinal outcomes in different domains warrants well-designed naturalistic studies. The aim of this study was to explore the 3-year effectiveness of rivastigmine treatment. Methods: The Swedish Alzhe
Freezing is a widely used method of preserving food products. Efforts are currently being directed towards improving the quality of the sensitive tissues of plant foods such as leaves, after freezing and thawing. One of the methods under investigation is the combination of vacuum impregnation (VI) with cryoprotectants and the application of a pulsed electric field (PEF) to the plant tissue prior t
Osteoarthritis and osteoporosis are two medical conditions involving the hip which affect the life quality of many people worldwide. These two diseases are diagnosed with 2D imaging by analysis of radiological measures, bone mineral density and joint space. Computed Tomography (CT) can provide 3D images of the hip, but has higher cost and imposes a higher radiation dose to the patient. Another op
This article is the product of a close chronological reading of the debate surrounding the so called ‘’ISIS-returnees’’ in Sweden during the spring of 2019. The debate itself, as well as the situation it concerned, has been treated as a discursive field where a securitization has been attempted and resisted by several actors. The study has found that an intersubjective struggle between these actor
Connecting science to political agenda-setting is essential for a sustainable transition and acceptable politics. This task is complicated by phenomena like post-truth, for which facts are a non-issue. However, post-truth is not the only issue. The practice of political spin, in which the significance of facts is reconstructed according to specific interests poses another threat to scientific cred
Due to the world’s growing population and an increase in food demand, new innovative food products need to be developed to maximize the use of limited farmland. Because of global warming and the fact that plant based products generate less greenhouse gases than meat based products, research should focus on new plant-based protein sources. Rapeseed press cake is a residue from rapeseed oil producti
The aim of this study was to determine in patients with HCV genotype 2 or 3 the performance at week 4 of two assays with different sensitivities for HCV RNA detection, for the prediction of SVR and stratification for treatment duration (14 and 24 weeks). Recruitment was from two trials comparing 14 and 24 weeks treatment to patients with rapid virological response (RVR) (n = 550). RVR was original
Background: The natriuretic peptides play an important role in salt homeostasis and blood pressure regulation. It has been suggested that obesity promotes a relative natriuretic peptide deficiency, but this has been a variable finding in prior studies and the cause is unknown. Aim: The aim of this study was to examine the association between obesity and natriuretic peptide levels and evaluate the
Abstract Background. Proteinuria is the hallmark of glomerular disease and non-selective proteinuria is often associated with progression to renal failure. The predictive value of urine IgG excretion was studied comprehensively in patients with nephrotic syndrome. In the present follow-up study, we examine the predictive value of IgG-uria in patients with idiopathic glomerular diseases with a wide
Background: The prevalence of blindness and visual impairment from glaucoma is influenced by the criteria used to define these entities, which differ between countries and regions, as well as among published reports. The objective of the present study was to ascertain the extent to which different criteria of blindness and visual impairment influence estimates of the number of patients classified
Even though a number of studies have shown that UV-B radiation inhibits plant growth and regulates the cell cycle progress, little is known about the molecular and cellular mechanisms. Here, we developed a synchronous root-tip cell system to investigate expression changes of cell cycle marker genes and DNA damage under UV-B radiation. Expression analysis of cell cycle marker genes revealed that G1
PURPOSE. To estimate the rate of visual field progression in open-angle glaucoma (OAG) subjects, by using data from population-based cross-sectional studies. METHODS. Subjects with OAG were identified in nine surveys of randomly sampled populations using standard criteria for glaucomatous optic neuropathy. Subjects were of European, African, Chinese, and Hispanic ethnicity. The measure of OAG dama
Background. Although muscle wasting may lead to decreased ammonia detoxification in cirrhosis, the potential role of lean mass depletion in hepatic encephalopathy (HE) has not been explored. Anemia, hormonal abnormalities, and psychological distress may contribute to cognitive dysfunction, but data on their potential relation to HE are limited. Methods. Data on 108 cirrhotic liver transplant candi
Background Primary Sjogren's syndrome (pSS) is an autoimmune rheumatic disease mainly characterised by focal mononuclear cell infiltration in the salivary and lacrimal glands, and by the symptoms xerostomia and keratoconjunctivitis sicca. Germinal centre-like structures (GC) are found in the minor salivary glands of approximately 25% of patients. In this study, we aimed to assess genetic variation
Objective To assess the use of lipid-lowering therapy in patients with known coronary heart disease (CHD), cerebrovascular disease or diabetes in a community-based population in Sweden considering expert recommendations. Methods A random sample of individuals aged >= 40 years who were surveyed in 1993-1994 were revisited 10 years later during 2003-2004 (n=724). A clinical investigation focused on
Aims: To explore the association between tooth loss and obesity in an adult Swedish population, and to investigate the influence of socioeconomy, life-style, and co-morbidity. Methods: A cross-sectional population health survey conducted in 2001-2005 in 2816 randomly selected Swedish men and women (age: 30-74 years; participation rate 76%). Main measures were; tooth loss: < 20 remaining teeth (sel
