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OBJECTIVE: Nonmotor symptoms are common in Parkinson's disease (PD). Health-related quality of life (HRQoL) is negatively affected by different factors, of which pain and sleep disturbances are important contributors. This study was performed to evaluate and describe subjective experiences of pain, sleeping patterns, and HRQoL in a cohort of PD patients with chronic pain.METHODS: A total of 45 par

Background: Tracheal intubation is a high-risk procedure in the critically ill, with increased intubation failure rates and a high risk of other adverse events. Videolaryngoscopy might improve intubation outcomes in this population, but evidence remains conflicting, and its impact on adverse event rates is debated. Methods: This is a subanalysis of a large international prospective cohort of criti

Objective: Ovarian carcinoma (OvCa) is more common in the elderly, but also affects the adolescent and young adult (AYA) generation, which refers to those aged 15–39 years. Although the characteristics of OvCa may differ between AYAs and non-AYAs, limited information is currently available on differences in prognostic factors. Therefore, we herein investigated prognostic factors for and the progno

Visual systems adapt to different light environments through several avenues including optical changes to the eye and neurological changes in how light signals are processed and interpreted. Spectral sensitivity can evolve via changes to visual pigments housed in the retinal photoreceptors through gene duplication and loss, differential and coexpression, and sequence evolution. Frogs provide an ex

Air pollution in urban environments exhibits large spatial and temporal variations due to high heterogeneous air flow and emissions. To address the complexity of local air pollutant dynamics, a comprehensive large-eddy simulation using the PALM model system v6.0 was conducted. The distribution of flow and vehicle emitted aerosol particles in a realistic urban environment in Malmö, Sweden, was stud

Changes in the net carbon sink of boreal forests constitute a major source of uncertainty in the future global carbon budget and, hence, climate change projections. The annual net ecosystem exchange of carbon dioxide (CO2) controlling the terrestrial carbon stock results from the small difference between respiratory CO2 release and the photosynthetic CO2 uptake by vegetation. The boreal forest, an

Many migratory animals use daylength, or photoperiod, to signal when to migrate and transition between annual phenological states. Whether animals use photoperiod as a temporal or spatial cue while migrating, however, requires additional empirical support. We used hatch-year dunnocks, Prunella modularis (a songbird), caught during their first migration in southern Sweden to elucidate whether migra

INTRODUCTION:The Environmental Determinants of Diabetes in the Young study follows an HLA risk selected birth cohort for celiac disease (CD) development using a uniform protocol. Children under investigation come from 6 different regions within Europe and the United States. Our aim was to identify regional differences in CD autoimmunity and CD cumulative incidence for children born between 2004 an

Poor management and excessive pumping of groundwater (GW) resources can lead to a significant decline in GW level, which may result in land deformation and compaction of compressible fine-grained soils within or adjacent to the aquifer. Soil compaction and resulting land deformation may be permanent if the GW level declines beyond the maximum historical stress. In extreme cases, the aquifer may lo

The population dynamics of urban animals has been so far remarkably understudied. At the same time, urban species’ population trends can provide important information on the consequences of environmental changes in cities. We modelled long-term population trends of 93 bird species breeding in urban areas in 16 European countries as a function of species’ traits, characterising variability in their

Background: Obsessive-compulsive disorder (OCD) and co-occurring posttraumatic stress disorder (PTSD) is associated with more severe and chronic OCD. However, findings regarding treatment effectiveness of cognitive behavioral treatment (CBT) with exposure and response prevention (ERP) with this comorbidity are mixed. Research aimed at understanding the precise barriers to OCD treatment effectivene

Background: Peritonitis is a major cause of morbidity in peritoneal dialysis (PD) and an independent risk factor for elevated all-cause mortality. The aims of this study were to report the incidence, trend, aetiology, and antimicrobial susceptibility of PD-associated peritonitis and catheter-related infections in South Sweden between 2011–2020.Methods: This population-based observational cohort st

OBJECTIVES: Many universities offer faculty development to support teachers in developing and improving clinical education in the health professions. Although research shows outcomes on individual levels after faculty development, little is known about its contribution to change within the organisation. To advance current faculty development and ensure that it can support wider educational change

Aquaporin-0 (AQP0) is the main water channel in the mammalian lens and is involved in accommodation and maintaining lens transparency. AQP0 binds the Ca2+-sensing protein calmodulin (CaM) and this interaction is believed to gate its water permeability by closing the water-conducting pore. Here, we express recombinant and functional human AQP0 in Pichia pastoris and investigate how phosphorylation

Rubella virus encodes a nonstructural polyprotein with RNA polymerase, methyltransferase, and papain-like cysteine protease activities, along with a putative macrodomain of unknown function. Macrodomains bind ADP-ribose adducts, a post-translational modification that plays a key role in host-virus conflicts. Some macrodomains can also remove the mono-ADP-ribose adduct or degrade poly-ADP-ribose ch

Arbetsgivarens rehabiliteringsansvar innebär, i samband med att en arbetstagare får nedsatt arbetsförmåga till följd av sjukdom, en skyldighet att utreda arbetsanpassnings- och rehabiliteringsmöjligheterna för att möjliggöra återgång i arbete. Rehabiliteringsansvaret regleras främst inom lagen om (1982:80) anställningsskydd, arbetsmiljölagen (1977:1160), socialförsäkringsbalken (2010:110) och kompThe employer's responsibility to rehabilitate is, in connection with an employee's reduced ability to work as a result of illness, an obligation to investigate work adaptation and rehabilitation possibilities to enable a return to work. The responsibility for rehabilitation is mainly regulated within the Employment Protection Act (LAS), the work environment act (AML), the social insurance

Bakgrund: Psykisk ohälsa kan innebära att en person upplever svårigheter att hantera vardagen och därmed påverka individens aktivitetsengagemang negativt. Aktivitetsengagemang innefattar en individs livsstil i form av rutiner, balans mellan olika typer av aktiviteter samt social delaktighet och är viktigt för hälsan, delaktighet och rehabiliteringen av psykisk ohälsa. Dock saknas det studier som kBackground: Mental illness can have a negative effect on a person's ability in coping with everyday life and thereby occupational engagement. Occupational engagement is important for health, participation and the rehabilitation of mental illness and includes an individual's lifestyle in the form of routines, balance between different types of activities and social participation. However, t

Bakgrund. Varje år drabbas omkring 25 000 personer i Sverige av stroke. Individer som drabbats av stroke får oftast funktionsnedsättningar som orsakar aktivitetsbegränsning i vardagslivet. Syfte. Syftet med studien var att undersöka vilka erfarenheter och upplevelser strokedrabbade personer har av förändringar i vardagliga aktiviteter.Metod. Studien genomfördes som en kvantitativ metod där instrum

Under de senaste 100-200 åren har tall (Pinus sylvestris) etablerats på många sydsvenska mos- sar. Eftersom tall trivs i relativt torra och näringsrika miljöer, ger detta en indikation på att grundvattennivån i mos- sarna har sänkts. Tre mossar i Kronobergs län, Småland, har valts ut för en dendrokronologisk och torvstratigrafisk undersökning för att se om det finns ytnära torvlager som vittnar omScots pine (Pinus sylvestris) can be found growing in many raised bogs in Småland, south Sweden, and these trees have been established during the last 100-200 years. Because pine prefers a relatively dry environment rich in nutrients, its presence indicates a lowering of the groundwater table. Three bogs in south Sweden were in- vestigated with dendrochronologic and peat stratigraphic methods to d