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This thesis presents studies on dissociation of two model molecules: Butadiene and Cyclopropane. Tunable synchrotron radiation was used to ionize or excite the molecules in the gas phase, and the momentum correlation of the resulting fragment ions were measured using a 3D momenta coincident ion spectroscopy. The experimental results were interpreted with the aid of ab-initio quantum calculation. T
Introduction: Assay discrepancy in factor VIII activity between the one-stage and the chromogenic assays has been described in approximately one third of patients with non-severe haemophilia A. Whether assay discrepancy may also occur in patients with haemophilia B remains unknown. Aim: This study compared the results from the one-stage and the chromogenic assays in patients with haemophilia B. Me
Background: High levels of blood glucose are thought to be associated with colorectal cancer (CRC) and hyperinsulinemia, an interstage in the development of CRC. The purpose of this study was to examine associations between incident CRC and blood glucose; plasma insulin; and the homeostasis model assessment for insulin resistance (HOMA2-IR), respectively, and to determine whether these association
A commercially available NaI(Tl) based spectrometer-dosimeter has been used to separate contributions of the terrestrial radionuclides (238U series, 232Th series and 40K) and 137Cs to the total ambient dose equivalent rate (ADER), Ḣ*(10) , outdoors. The device had been initially calibrated by the manufacturer to measure: 1) the total ADER; 2) activity concentrations of 226Ra, 232Th, 40K and ‘effec
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) has been associated with multiple metabolic abnormalities. By applying a non-targeted metabolomics approach, we aimed at investigating whether serum metabolite profile that associates with NAFLD would differ in its association with NAFLD-related metabolic risk factors. Methods & Results: A total of 233 subjects (mean ± SD: 48.3 ±
BACKGROUND: Endovascular thrombectomy (EVT) is standard of care for anterior circulation acute ischemic stroke (AIS) caused by large vessel occlusion (LVO), but data on nationwide performance in routine healthcare are sparse. The study aims were to describe EVT patients with LVO AIS, analyze mortality and functional outcome, and compare results with randomized controlled trials (RCTs).METHODS: Dat
Thousands of species migrate [1]. Though we have some understanding of where and when they travel, we still have very little insight into who migrates with whom and for how long. Group formation is pivotal in allowing individuals to interact, transfer information, and adapt to changing conditions [2]. Yet it is remarkably difficult to infer group membership in migrating animals without being able
The measurement of innovation is a challenging task for management accounting practitioners and researchers alike. To tackle this task, key performance indicators (KPIs) can be used to measure and follow up innovation. This case study shows how KPIs are used to measure innovation after strategic changes due to competitive pressures. The findings of this study indicate that KPIs in innovation are uMeasuring innovation is a challenging but essential task to improve business performance. To tackle this task, key performance indicators (KPIs) can be used to measure and monitor innovation. The objective of this study is to explore how KPIs, designed for measuring innovation, are used in practice. To achieve this objective, the author draws upon literature on business performance in accounting a
Recent outlooks suggest a long-term relevance of internal combustion engines for both power generation and transportation. Nonetheless, stringent pollutant reduction requirements combined with new CO2 mandates draws a challenging scenario, requiring intensive research and development activities to develop and optimize combustion modes to fulfill these requirements. Among the recent advancements, t
‘Modern astronomy’ was introduced to Siam (present-day Thailand) when the Belgian Jesuit missionary-astronomer Father Antoine Thomas carried out astronomical observations in 1681 and 1682 in order to determine the latitude and longitude of Ayutthaya. Three years later a contingent of French Jesuit missionary astronomers observed a total lunar eclipse from Lop Buri, which marked the start of an int
Avian communities play a pivotal role in Arctic ecosystems and birds have become the key model taxa for climate change research. Due to funding priorities, Arctic passerines have been studied less intensively than waterfowl and shorebirds. In our study, we aim to partly fill this gap and look at the change in passerine community species composition in the Chaun River Delta in Northeast Siberia (68
UNLABELLED: There are three main methods used to assay factor VIII (FVIII) activity: the one-stage and two-stage clotting assays and the two-stage chromogenic method. The most commonly used assay for the diagnosis of haemophilia A is the automated one-stage FVIII assay. The classical two-stage FVIII assays are less frequently used. The chromogenic FVIII:C assay is a variant of the two-stage assay.
OBJECTIVE: To characterize 414 patients with primary SS who developed hematological malignancies and to analyze how the main SS- and lymphoma-related features can modify the presentation patterns and outcomes.METHODS: By January 2021, the Big Data Sjögren Project Consortium database included 11 966 patients fulfilling the 2002/2016 classification criteria. Hematological malignancies diagnosed acco
BackgroundOncoMasTR is a recently developed multigene prognostic test for early-stage breast cancer. The test has been developed in a kit-based format for decentralized deployment in molecular pathology laboratories. The analytical performance characteristics of the OncoMasTR test are described in this study.MethodsExpression levels of 6 genes were measured by 1-step reverse transcription-quantita
AimTo quantify the responses of alpha and beta diversity to multivariate gradients, incorporating variation in environmental and management variability in coastal dune slacks.LocationUnited Kingdom dune slacks.MethodsPlant community composition, plant nutrient status and soil characteristics were measured for 164 quadrats in 41 dune slacks across 12 coastal sand dune systems. Data were collated on
Background: The Parkinson Disease (PD) Home Diary (HD) is a commonly used clinical outcome measure, but it has not been extensively compared to direct assessments by experienced observers.Objective: Validation of patient-reported HD by investigating the agreement between motor state assessments by patients and observers.Methods: This observational study included patients with PD and motor fluctuat
