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Ensemble estimates of global wetland methane emissions over 2000-2020

Due to ongoing climate change, methane (CH4) emissions from vegetated wetlands are projected to increase during the 21st century, challenging climate mitigation efforts aimed at limiting global warming. However, despite reports of rising emission trends, a comprehensive evaluation and attribution of recent changes remains limited. Here we assessed global wetland CH4 emissions from 2000-2020 based

Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib

Tumors with anaplastic lymphoma kinase (ALK) fusion rearrangements, including non-small-cell lung cancer and anaplastic large cell lymphoma, are highly sensitive to ALK tyrosine kinase inhibitors (TKIs), underscoring the notion that such cancers are addicted to ALK activity. Although mutations in ALK are heavily implicated in childhood neuroblastoma, response to the ALK TKI crizotinib has been dis

The Ontology and Epistemologies of a Plant : The cannabis community in Buenos Aires, Argentina

Cannabisaktivism, en del av Argentinas bredare tradition av sociala rörelser, har utvecklats till ett dynamiskt fält för motstånd och påverkansarbete – särskilt när det gäller medicinsk cannabis, som hamnade i fokus år 2015. Faktum är att min avhandling tog sin startpunkt i och med att jag etablerade kontakt med Mama Cultiva, en sammanslutning av mödrar, som spelade en aktiv roll i skapandet av enCannabis activism, which is embedded in Argentina’s broader tradition of social movements, has become a dynamic field of resistance and advocacy, particularly regarding medicinal cannabis, which came into focus in 2015. Indeed, the research for my thesis began by establishing contact with Mama Cultiva, a mothers’ organisation that played an active role in the creation of a new cannabis law and dra

Preliminary Assessment of Hydrological Heritage in North Macedonia : A Novel Contribution to Geodiversity Protection

This study inventories, classifies, and evaluates the hydrological heritage of North Macedonia, categorizing key features into four main groups: (1) river basins, including rivers and waterfalls; (2) springs, classified as karst and thermal; (3) natural lakes, subdivided into tectonic, glacial, landslide, denudation, and karst types; and (4) marshes. Recent measurements have shown a significant de

Minerals, microbes and melanin drive differential incorporation of fungal necromass carbon and nitrogen into mineral-associated organic matter

Despite the importance of mineral-associated organic matter (MAOM) in long-term soil carbon (C) and nitrogen (N) persistence, and the significant contribution of fungal necromass to this pool, the factors controlling the formation of fungal-derived MAOM remain unclear. This study investigated how fungal necromass chemistry, specifically melanin, interacts with soil mineral properties and microbial

Development and Validation of a Risk Prediction Model for Esophageal Squamous Cell Carcinoma Using Cohort Studies

INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure to readily available risk factors to identify high-risk individuals of ESCC.METHODS: Competing risk regression modeling was used to develop a risk prediction model. Individuals' ab

Short-range exciton couplings in LH2 photosynthetic antenna proteins studied by high hydrostatic pressure absorption spectroscopy

The effects of high hydrostatic pressure (up to 8 kbar) on bacteriochlorophyll a Qy electronic absorption bands of LH2 photosynthetic antenna complexes have been studied at ambient temperature. A variety of samples were studied, including intact membranes and isolated complexes from wild type and mutant photosynthetic bacteria Rhodobacter sphaeroides, Rhodopseudomonas acidophila, and Rhodospirillu

Var sitter kompetensen? En studie om villkor för lärande i arbetet

Projektarbete har blivit en vanlig arbetsform i organisationer. Alfa Laval är ett företag som utnyttjar projektarbete för att utveckla verksamheten. Projekten leder dock inte alltid till de resultat som förväntas. För att analysera denna diskrepans vill jag lyfta fram projektledarnas uppfattning om sin arbetssituation. Studiens syfte är att belysa och analysera villkor för projektledarnas kompeten

Employer Branding och Generation Y. Vilken betydelse har generationstillhörigheten för organisationers Employer Branding?

Bakgrund/Problem: I samband med generationsskiftet på arbetsmarknaden uppstår frågan hur arbetsgivarna ur ett rent strategiskt perspektiv kan ta ställning till Generation Y (födda under andra halvan av sjuttiotalet fram till ca år 2000) i arbetslivet. Generation Y verkar nämligen ha en förändrad syn jämfört med äldre generationer när det gäller hur man ser på arbetets roll i livet. Företagen måste

En undersökning om fritidshemspersonalens uppfattning av den kunskapsspridning som sker inom ett arbetslag

Vi har genom tidigare arbetslivserfarenheter sett att det inte alltid är lätt sprida inkommande och inneboende kunskap vidare inom arbetslaget. Med detta som utgångspunkt har vi valt att göra en kvalitativ fallstudie av ett fritidshem. Där har vi undersökt hur innehavd och inkommande kunskap sprids vidare till de övriga i arbetslaget. Vår tanke med undersökningen var att se, om, och på vilket sätt

Erasmus studenter i Lund: en empirisk undersökning av identitetsförändringen

Det här arbetet är en empirisk undersökning av Erasmus studenter i Lund under läsåret 2006/2007. Arbetet fokuserar på identitetsförändringen av Erasmus studenterna under tiden i Lund. Undersökningen baserar på George Herbert Meads, Peter Bergers och Thomas Luckmanns teorier om identitetsutvecklingen. Det empiriska materialet baserar på tre intervjuer, email och materialen ur "gruppen" j

SeeMe at the crosswalk : Before-after study of a pedestrian crosswalk warning system

SeeMe is a pedestrian crosswalk warning system with automatic pedestrian detection that is mounted on crosswalk signs. Amber flashing lights are activated when pedestrians are approaching or crossing the crosswalk. The aim is to attract motorists’ attention, to improve yielding behavior and to reduce conflicts. A before-after study with a matched comparison group has been conducted in the Norwegia

Multiple independent origins of intermediate species between Sorbus aucuparia and S. hybrida (Rosaceae) in the Baltic region

Populations intermediate between the diploid and sexual Sorbus aucuparia and the tetraploid and facultative apomictic Sorbus hybrida are scattered in coastal regions of southern Scandinavia. Our aims were to investigate whether these populations were of local and independent origins, whether they were morphologically and molecularly distinct from each other and whether they could give rise to cons

Small changes in timing of breeding among subarctic passerines over a 32-year period

Many bird populations in temperate regions have advanced their timing of breeding in response to a warming climate in recent decades. However, long-term trends in temperature differ geographically and between seasons, and so do responses of local breeding populations. Data on breeding bird phenology from subarctic and arctic passerine populations are scarce, and relatively little data has been rec

Fractional flow reserve-guided percutaneous coronary intervention vs. medical therapy for patients with stable coronary lesions : meta-analysis of individual patient data

Aims: To assess the effect of fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) with contemporary drug-eluting stents on the composite of cardiac death or myocardial infarction (MI) vs. medical therapy in patients with stable coronary lesions. Methods and results: We performed a systematic review and meta-analysis of individual patient data (IPD) of the three available

Prostate cancer risk-associated single-nucleotide polymorphism affects prostate-specific antigen glycosylation and its function

BACKGROUND: Genetic association studies have reported single-nucleotide polymorphisms (SNPs) at chromosome 19q13.3 to be associated with prostate cancer (PCa) risk. Recently, the rs61752561 SNP (Asp84Asn substitution) in exon 3 of the kallikrein-related peptidase 3 (KLK3) gene encoding prostate-specific antigen (PSA) was reported to be strongly associated with PCa risk (P 2.3 108). However, the bi

Dialog eller dynamit : Viktor Rydberg och August Strindberg – förtryckets fiender

Trots att Viktor Rydberg och August Strindberg tillhörde olika generationer var de verksamma samtidigt under drygt 25 års tid. För första gången får vi här en grundlig inblick i deras åsikter om varandra samt en uppfattning om de impulser de fått från varandras författarskap. Studien bygger på brevmaterial och ingående textanalyser. Under 1880-talet när motståndet mot konservatismen polariserades,

Type and frequency of side effects during PC6 acupuncture : observations from therapists and patients participating in clinical efficacy trials of acupuncture

BACKGROUND: Many therapists practise PC6 acupuncture for emesis (nausea and vomiting) during pregnancy, different cancer therapies, palliative care, after surgery, or to induce relaxing effects in general. Knowledge of side effects is central to shared decision-making.AIM: To describe the type and frequency of side effects and the level of needle-induced pain during PC6 acupuncture.METHODS: We inc

Higher Flexibility of Glu-172 Explains the Unusual Stereospecificity of Glyoxalase i

Despite many studies during the latest two decades, the reason for the unusual stereospecificity of glyoxalase I (GlxI) is still unknown. This metalloenzyme converts both enantiomers of its natural substrate to only one enantiomer of its product. In addition, GlxI catalyzes reactions involving some substrate and product analogues with a stereospecificity similar to that of its natural substrate re