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Relationships between fungal uptake of ammonium, fungal growth and nitrogen availability in ectomycorrhizal Pinus sylvestris seedlings
Nitrogen deposition and intentional forest fertilisation with nitrogen are known to affect the species composition of ectomycorrhizal fungal communities. To learn more about the mechanisms responsible for these effects, the relations between fungal growth, nitrogen uptake and nitrogen availability were studied in ectomycorrhizal fungi in axenic cultures and in symbiosis with pine seedlings. Effect
Evidence for electrical remodelling of the atrial myocardium in patients with atrial fibrillation. A study using the monophasic action potential recording technique.
Sample preparation effects on the compaction properties of Swedish fine-grained tills
Fine-grained tills are a dominant feature of the drift geology of Sweden. Until recently their use in earthworks applications has been limited due to the plentiful supply of naturally occurring gravel and crushed rock, and their high sensitivity to moisture content change which often leads to the view that fine-grained tills are problem soils. Environmental and economic factors are, however, leadi
Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.
Holocene palaeoecology along the Blekinge coast, SE Sweden, and implications for climate and sea-level changes
To investigate the Holocene vegetation history and shoreline displacement along the southeastern Swedish coast, two radiocarbon dated pollen, macrofossil and mineral magnetic sequences were studied in the western Blekinge coast: Hunnemara Lake and Smygen Bay. Both pollen records show mosaic vegetation with grasslands, heaths and woodlands prior to 11 300 cal. BP. Pinus-dominated mixed forest was i
Is Levoglucosan a Suitable Quantitative Tracer for Wood Burning? - Comparison with Receptor Modeling on Trace Elements in Lycksele, Sweden
Particle emissions from residential wood combustion in small communities in Northern Sweden can sometimes increase the ambient particle concentrations to levels comparable to densely trafficked streets in the center of large cities. The reason for this is the combination of increased need for domestic heating during periods of low temperatures, leading to higher emission rates, and stable meteorol
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus
We analyzed a comprehensive set of single-nucleotide polymorphisms (SNPs) and length polymorphisms in the interferon regulatory factor 5 (IRF5) gene for their association with the autoimmune disease systemic lupus erythematosus (SLE) in 485 Swedish patients and 563 controls. We found 16 SNPs and two length polymorphisms that display association with SLE (P < 0.0005, OR > 1.4). Using a Bayesian mod
Boronate-containing copolymers: Polyelectrolyte properties and sugar-specific interaction with agarose gel
Copolymers of N-acryloyl-m-aminophenylboronic acid (NAAPBA) with acryamide (AA), N,N-dimethylacrylamide (DMAA), and N-isopropylacrylamide (NIPAM) were found to adsorb on cross-linked agarose gel (Sepharose CL-6B) in the pH range from 7.5-9.2, due to specific boronate-sugar interactions. The molar percentages of phenylboronic acid (PBA) groups in the boronate-containing copolymers (BCCs), as estima
Feeding, reproduction and toxin accumulation by the copepods Acartia bifilosa and Eurytemora affinis in the presence of the toxic cyanobacterium Nodularia spumigena
Feeding, reproduction and accumulation of cyanobacterial toxins by the calanoid copepods Acartia bifilosa and Eurytemora affinis were studied during a cruise in the northern Baltic Sea. The experiments were carried out using both mixtures of natural plankton communities, mixtures containing the toxic Nodularia spumigena, and diets containing only the toxic cyanobacterium. Both copepod species had
Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib
Tumors with anaplastic lymphoma kinase (ALK) fusion rearrangements, including non-small-cell lung cancer and anaplastic large cell lymphoma, are highly sensitive to ALK tyrosine kinase inhibitors (TKIs), underscoring the notion that such cancers are addicted to ALK activity. Although mutations in ALK are heavily implicated in childhood neuroblastoma, response to the ALK TKI crizotinib has been dis
Precuneus Activity during Retrieval Is Positively Associated with Amyloid Burden in Cognitively Normal Older APOE4 Carriers
Preliminary Assessment of Hydrological Heritage in North Macedonia : A Novel Contribution to Geodiversity Protection
This study inventories, classifies, and evaluates the hydrological heritage of North Macedonia, categorizing key features into four main groups: (1) river basins, including rivers and waterfalls; (2) springs, classified as karst and thermal; (3) natural lakes, subdivided into tectonic, glacial, landslide, denudation, and karst types; and (4) marshes. Recent measurements have shown a significant de
Minerals, microbes and melanin drive differential incorporation of fungal necromass carbon and nitrogen into mineral-associated organic matter
Despite the importance of mineral-associated organic matter (MAOM) in long-term soil carbon (C) and nitrogen (N) persistence, and the significant contribution of fungal necromass to this pool, the factors controlling the formation of fungal-derived MAOM remain unclear. This study investigated how fungal necromass chemistry, specifically melanin, interacts with soil mineral properties and microbial
Development and Validation of a Risk Prediction Model for Esophageal Squamous Cell Carcinoma Using Cohort Studies
INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure to readily available risk factors to identify high-risk individuals of ESCC.METHODS: Competing risk regression modeling was used to develop a risk prediction model. Individuals' ab
Short-range exciton couplings in LH2 photosynthetic antenna proteins studied by high hydrostatic pressure absorption spectroscopy
The effects of high hydrostatic pressure (up to 8 kbar) on bacteriochlorophyll a Qy electronic absorption bands of LH2 photosynthetic antenna complexes have been studied at ambient temperature. A variety of samples were studied, including intact membranes and isolated complexes from wild type and mutant photosynthetic bacteria Rhodobacter sphaeroides, Rhodopseudomonas acidophila, and Rhodospirillu
Markvattenhalt och temperatur i sandig jordbruksmark vid Ilstorp, centrala Skåne : en mätnings- och modelleringsstudie
Populärvetenskaplig sammanfattning: Vinderosion på jordbruksmark har länge varit ett välkänt faktum trots att någon utförligare undersökning om dess omfattning och skadeverkan inte tidigare genomförts. Mot bakgrund av detta har därför ett nordeuropeiskt projekt, WEELS (Wind Erosion on European Light Soils), dragits i gång som syftar till kartlägga vinderosionen på sandig jordbruksmark i norra Euro
Combined computational and crystallographic study of the oxidised states of [NiFe] hydrogenase
[NiFe] hydrogenases catalyse the reaction H2 <-> 2H(+) + 2e(-). Several states of the enzyme have been observed by spectroscopic methods. Among these, the two most oxidized states, called the unready Ni-A and Ni-SU states, have been especially intriguing, because they take a much longer time to activate than the corresponding ready Ni-B and Ni-SI states. It has recently been suggested that the unr
Allogeneic haematopoietic stem cell transplantation for metastatic renal carcinoma in Europe
Background: An allogeneic antitumour effect has been reported for various cancers. We evaluated the experience of allogeneic haematopoietic stem cell transplantation (HSCT) for renal cell carcinoma (RCC) in 124 patients from 21 European centres. Patients and methods: Reduced intensity conditioning and peripheral blood stem cells from an HLA-identical sibling (n = 106), a mismatched related (n = 5)
SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density
Context: SHBG regulates free sex steroid levels, which in turn regulate skeletal homeostasis. Twin studies have demonstrated that genetic factors largely account for interindividual variation in SHBG levels. Glucuronidated androgen metabolites have been proposed as markers of androgenic activity. Objective: Our objective was to investigate whether polymorphisms in the SHBG gene promoter [(TAAAA)(n
