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The dispersion of repolarization in patients with ventricular tachycardia. A study using simultaneous monophasic action potential recordings from two sites in the right ventricle
The role of increased dispersion of repolarization in the genesis of torsade de pointes and ventricular fibrillation has been well recognized generally, but not in the genesis of monomorphic ventricular tachycardia (VT). Monophasic action potentials (MAP) were therefore recorded simultaneously from the right ventricular (RV) apex (RVA) and outflow tract (RVOT) during sinus rhythm, RV pacing and pr
Effect of dofetilide on cardiac repolarization in patients with ventricular tachycardia. A study using simultaneous monophasic action potential recordings from two sites in the right ventricle
Monophasic action potentials (MAP) were simultaneously recorded from the right ventricular (RV) apex (RVA) and the outflow tract (RVOT) before and after an infusion of dofetilide in 10 patients with documented ventricular tachycardia. After the drug infusion, the MAP duration (MAPd), repolarization time, and corrected QT interval were significantly prolonged during sinus rhythm, RV pacing, and RV
Age-related dynamics in biodiversity and carbon cycling of Icelandic woodlands (ICEWOODS): Experimental design and site descriptions
A form is simply something which allows something else to be transported from one site to another. Murray Guy Gallery, New York
Urban underwater ERT for site investigation in lake Mälaren, Sweden
An underwater ERT survey was made along a planned road tunnel for The Stockholm Bypass Project (Förbifart Stockholm). The aim was to assess the ability to identify variations in the depth of the bottom sediments, as well as variations in rock quality and the possible presence of weak zones in the rock. Reference data from a seismic survey and geotechnical drilling was used for evaluation the resul
Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interaction
The heterodimer HIF-1α (hypoxia inducible factor)/HIF-β (also known as ARNT-aryl hydrocarbon nuclear translocator) is a key mediator of cellular response to hypoxia. The interaction between these monomer units can be modified by the action of small molecules in the binding interface between their C-terminal heterodimerization (PasB) domains. Taking advantage of the presence of several cysteine res
Joint inversion of lake-floor electrical resistivity tomography and boat-towed radio-magnetotelluric data illustrated on synthetic data and an application from the Äspö Hard Rock Laboratory site, Sweden
The electrical resistivity tomography (ERT) method provides moderately good constraints for both conductive and resistive structures, while the radio-magnetotelluric (RMT) method is well suited to constrain conductive structures. Additionally, RMT and ERT data may have different target coverage and are differently affected by various types of noise. Hence, joint inversion of RMT and ERT data sets
Underwater ERT surveying in water with resistivity layering with example of application to site investigation for a rock tunnel in central Stockholm
We present an approach to underwater electrical resistivity tomography surveying under conditions with several water layers with different resistivity in the water above the electrode layout. The approach is verified against a synthetic model example and tested in full scale on data from a field survey. The field survey was carried out in central Stockholm as part of pre-investigations for a new m
Equivalent Black Carbon from fossil fuel and biomass burning sources at European rural background sites assessed by high time resolution measurements and modelling
The Mesolithic Site in Hög in a South-Scandinavian Perspective : A snap shot from the Early Kongemose Kultur
A 3D Digital Approach for the Study and Presentation of the Bisarcio Site
Submerged sites under threat : Defining new strategies for their monitoring and preservation
New excavations at the central site of Uppåkra, in the very south of Sweden
BVOC ecosystem flux measurements at a high latitude wetland site
A novel mutation on the transferrin gene abolishes one N-glycosylation site and alters the pattern of transferrin isoforms, mimicking that observed after excessive alcohol consumption.
In the process of obtaining a driver's license, a healthy 28year old man presented increased levels of disialo-transferrin (TF) (approx. 20%, ref. value<2) by HPLC analysis of TF isoforms (%CDT), while other markers of excessive alcohol consumption (PEth, MCV and γ-GT) were in the normal range. The objective of this study was to determine the cause of the increased %CDT levels.
Identification of covalent binding sites of ethyl 2-cyanoacrylate, methyl methacrylate and 2-hydroxyethyl methacrylate in human hemoglobin using LC/MS/MS techniques.
Acrylates are used in vast quantities, for instance in paints, adhesive glues, molding. They are potent contact allergens and known to cause respiratory hypersensitivity and asthma. Here we study ethyl 2-cyanoacrylate (ECA), methyl methacrylate (MMA) and 2-hydroxyethyl methacrylate (HEMA). There are only limited possibilities to measure the exposure to acrylates, especially for biological monitori