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Evidence of Site-Specific and Male-Biased Germline Mutation Rate in a Wild Songbird
Germline mutations are the ultimate source of genetic variation and the raw material for organismal evolution. Despite their significance, the frequency and genomic locations of mutations, as well as potential sex bias, are yet to be widely investigated in most species. To address these gaps, we conducted whole-genome sequencing of 12 great reed warblers (Acrocephalus arundinaceus) in a pedigree s
Spaces of becoming: the Stockholm Film Workshop as a transnational site of film production
HnRNP G prevents inclusion on the HPV16 L1 mRNAs of the central exon between splice sites SA3358 and SD3632
Mapping of the high molecular weight kininogen binding site of prekallikrein. Evidence for a discontinuous epitope formed by distinct segments of the prekallikrein heavy chain
Prekallikrein, a glycoprotein involved in contact phase activation, circulates in plasma in the form of a binary complex with high molecular weight kininogen (H-kininogen). The binding to H-kininogen is mediated by the prekallikrein heavy chain consisting of four repetitive domains, A1-A4. To define more precisely the region(s) involved in kininogen binding, we have employed an affinity cross-link
Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci
Validation of surgical site infection registration in colorectal surgery
Smoking increases donor site complications in breast reconstruction with DIEP flap
Objective: Reconstruction with deep inferior epigastric perforator flap (DIEP) is considered to be the first choice for autologous breast reconstruction. The primary aims of this retrospective study were to find out if differences in smoking habits and BMI are useful predictors for postoperative complications in DIEP surgery. Methods: Three hundred and one patients were included. Data regarding sm
Building-site camps and extended work hours : A two-week monitoring of self-reported physical exertion, fatigue, and daytime sleepiness
Anthropogenic and biogenic influence on VOC fluxes at an urban background site in Helsinki, Finland
Groundwater geochemistry of a nitrate-contaminated agricultural site
In situ observations of the isotopic composition of methane at the Cabauw tall tower site
High-precision analyses of the isotopic composition of methane in ambient air can potentially be used to discriminate between different source categories. Due to the complexity of isotope ratio measurements, such analyses have generally been performed in the laboratory on air samples collected in the field. This poses a limitation on the temporal resolution at which the isotopic composition can be
Upper Pleistocene palaeoenvironmental changes at the Zwierzyniec site, Central Poland
EFFECTIVE AND EFFICIENT WASTE SORTING IN CONSTRUCTION SITES
Severe retinal degeneration at an early age in Usher syndrome type 1B associated with homozygous splice site mutations in MYO7A gene
Association between a polymorphism affecting an AP1 binding site in the promoter of the TCIRG1 gene and bone mass in women
The TCIRG1 gene encodes a component of the osteoclast vacuolar proton pump and previous work has shown that inactivating mutations of the TCIRG1 cause autosomal recessive osteopetrosis. In order to determine whether allelic variation in TCIRG1 contributes to the regulation of bone mineral density (BMD) in normal individuals, we studied the relationship between polymorphisms of TCIRG1 and BMD in a