Filetype
A Tale of Two Proteins: SepF2 and SepF3 You might have heard of antibiotic resistance, which is one of the biggest public health issues of our time. In addition to the measures that should be taken at all levels of society to combat this issue, research to identify new antimicrobial targets to alleviate the rapid emergence of antibiotic resistance has become crucial. Cell division proteins in bac
Brevmall Postadress: Box 117, 221 00 Lund Besöksadress: Paradisgatan 5B Telefon dir 046-222 91 68, växel 046-222 00 00 E-post asa.ekberg@stu.lu.se Educat ion Board Regulations for the establishment, discontinuation and quality assurance of open web-based learning (Massive Open Online Courses, MOOCs) at Lund University Open web-based learning (MOOCs) is regulated in the Higher Education Ordinance (
The monosaccharide anhydrides (MAs) levoglucosan, galactosan and mannosan are products of incomplete combustion and pyrolysis of cellulose and hemicelluloses, and are found to be major constituents of biomass burning (BB) aerosol particles. Hence, ambient aerosol particle concentrations of levoglucosan are commonly used to study the influence of residential wood burning, agricultural waste burning
Popular Abstract in Swedish I mitt doktorandprojekt har jag studerat den fästingspridda bakterien Borrelia och dess värddjur skogssork. Det övergripande syftet har varit att kartlägga den genetiska variationen i den delen av immunförsvaret som tar hand om bakterieinfektioner, som till exempel borrelia. I alla ryggradsdjur finns ett specifikt immunförsvar som kan identifiera små proteinbitar från eThe major histocompatibility complex (MHC) class IIB genes exhibit extensive allelic polymorphism, most likely maintained by pathogen-mediated balancing selection (PMBS). PMBS may operate in the form of heterozygote advantage (HA), and/or through the interaction of pathogens and specific MHC alleles via fluctuating selection (FS) or negative frequency-dependent selection (NFDS). In particular, NFD
Introduction: Vertebral fracture is a strong risk factor for future spine and hip fractures; yet recent data suggest that only 5-20% of subjects with a spine fracture are identified in primary care. We aimed to develop easily applicable algorithms predicting a high risk of future spine fracture in men and women over 50 years of age. Methods: Data was analysed from 5,561 men and women aged 50+ year
There is increasing evidence that fermentation in the large intestine is important for health, and that health-promoting effects are mediated by fermentation products such as butyric and propionic acid. As the formation of carboxylic acids (CAs) from various carbohydrates reaching the colon has been shown to vary, it is of great interest to identify food factors that could be of importance to this
Since publication of the 1998 UNEP Assessment, there has been continued rapid expansion of the literature on UV-B radiation. Many measurements have demonstrated the inverse relationship between column ozone amount and UV radiation, and in a few cases long-term increases due to ozone decreases have been identified. The quantity, quality and availability of ground-based UV measurements relevant to a
The thesis concerns modeling, simulation and numerical analysis of heat and mass transport, and fluid flow in ducts of both solid oxide fuel cells (SOFCs) and proton exchange membrane fuel cells (PEMFCs). The unique fuel cell boundary conditions (thermal, mass) for the flow ducts in fuel cells are identified and applied. Various duct configurations have been studied, such as rectangular and trapez
Cell fate reprogramming towards pluripotency or alternative somatic cell-types has highlighted the plasticity of adult somatic cells, providing new technologies to generate desired cell types for tissue repair or for disease modeling. There is momentum to bring these concepts to immunology by specifying unique immune cellular identities that set in motion immune responses. Dendritic cells (DCs) ar
The role of Apolipoprotein A-I (ApoA-I), the main protein component of HDL, in cholesterol transport and metabolism is well known and has been studied for more than four decades. More recently, ApoA-I protein has been shown to also have a positive role in glucose control by both stimulation of glucose uptake by muscles and by increasing glucose-stimulated pancreatic insulin secretion. Two of the f
When doped into solid state transparent crystals, rare-earth ions can have optically excited states with milliseconds coherence time and up to six hours coherence time for hyperfine levels after being cooled down to liquid helium temperature. This long coherence property makes them unique as solid state material and attractive for quantum information applications.The rare-earth ions have narrow ho
Background: Poor housing conditions, such as poor building materials and weak structures as well as high levels of indoor air pollution, are important risk factors for a broad range of diseases, including acute respiratory infections (ARI). In mining areas, research on the determinants of respiratory health predominantly focuses on exposures to outdoor air pollutants deriving from mining operation
Following the impressive development of bulk lead-based perovskite photovoltaics, the “perovskite fever” did not spare nanochemistry. In just a few years, colloidal cesium lead halide perovskite nanocrystals have conquered researchers worldwide with their easy synthesis and color-pure photoluminescence. These nanomaterials promise cheap solution-processed lasers, scintillators, and light-emitti
Numerous barbiturates, such as (±)-pentobarbital, reversibly enhance the affinity for equilibrium binding of [3H]diazepam to well-washed rat cortical membranes in a chloride-dependent and picrotoxinin-sensitive manner [Leeb-Lundberg et al., Proc. Natl. Acad. Sci. U.S.A. 77:7468-7472 (1980)]. The chemical specificity and stereospecificity of this barbiturate effect in vitro has been examined in det
Collagen is the main organic building block of musculoskeletal tissues. Despite collagen being their smallest load bearing unit, these tissues differ significantly in mechanical function and properties. A major factor behind these differences is their hierarchical organization, from the collagen molecule up to the organ scale. It is thus of high importance to understand the characteristics of each
Background. A once commonly held belief was that surgery is too complicated, too expensive, and too ineffectively addressing a too minor proportion of the burden of disease to deserve priority in a setting of scarce healthcare resources in low- and middle-income countries. Yet, essential surgical care can be as highly cost-effective as other common public health interventions, and surgical service
This paper presents the results of the 2022 Groundwater Time Series Modelling Challenge, where 15 teams from different institutes applied various data-driven models to simulate hydraulic-head time series at four monitoring wells. Three of the wells were located in Europe and one was located in the USA in different hydrogeological settings in temperate, continental, or subarctic climates. Participa
This paper presents the results of the 2022 Groundwater Time Series Modelling Challenge, where 15 teams from different institutes applied various data-driven models to simulate hydraulic-head time series at four monitoring wells. Three of the wells were located in Europe and one was located in the USA in different hydrogeological settings in temperate, continental, or subarctic climates. Participa
This Master’s thesis is performed on behalf of Alfa Laval, a multinational company providing technological products and services.
Alfa Laval has in the past had a lot of successful mergers, but there were also those cases that led to sell off and those that had potential to add more value than was actually realized. In the common case, it has been shown that 60-70 per cent of M&As fall sho
Popular Abstract in Swedish Deponier (soptippar) har förändrats kraftigt de senaste decennierna. Detta beror främst på ändrad lagstiftning vilken i sin tur till stor del bygger på en önskan att skydda miljön. Dock har lag¬stiftningen implementerats utan riktig kännedom om dess konsekvenser för utsläppen från deponier på lång sikt. För att öka förståelsen för konsekvenserna genomfördes det forskninWaste management in Europe has changed, mainly as a result of stricter regulations, most notably the European Landfill Directive 1999/31/EC. In Sweden, landfill tax and a ban on the landfilling of waste with total organic carbon content over 10 % have diverted large amounts of waste from landfills. The biogeochemistry of landfills has changed due to their reduced organic content. The research pres
