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An exploratory study of Middle Stone Age and Later Stone Age site locations in Kenya’s Central Rift Valley using landscape analysis : a GIS approach

The Kenyan central rift has witnessed dramatic climatic changes over relatively short periods of time in response to global climatic changes, with the water levels of the lakes within the rift rising and falling with these changing conditions. There is considerable evidence showing extreme wet and dry phases throughout their existence. These wet and dry phases also influenced the vegetation cover,

Detection by near-infrared spectroscopy of large lipid cores at culprit sites in patients with non-st-segment elevation myocardial infarction and unstable angina

ObjectiveThis study was performed to assess the lipid burden of culprit lesions in non-ST-segment elevation myocardial infarction (non-STEMI) and unstable angina (UA). BackgroundA recent intracoronary near-infrared spectroscopy (NIRS) study showed 85% of STEMI culprit lesions have a maximum lipid core burden index in 4-mm (maxLCBI(4mm))400. Whether culprit lesions in non-STEMI and UA are character

Management of saltpans as potential foraging sites for shorebirds

Abstract Estuaries and salt marshes are important wetlands used by waterbirds during winter and migration. However, many salt-marshes have been transformed into salinas, which currently function as high-tide roosts. Since traditional salt production is no longer profitable, many salinas have been abandoned or converted into aquaculture potentially becoming less attractive to waders. In this study

Russian internet news sites, 2008–2018 : Fostering an informed citizenry?

Since Perestroika, Russian journalism has gone through a liberalization. However, the short lived apex of journalistic freedom that took place in the late 1980s and early 1990s was followed by a setback in particular since Putin’s accession to power in 2000. The situation for the freedom of the daily press has stagnated. Despite this, the findings based on qualitative text analysis of news article

Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation

ATP phosphoribosyltransferase catalyses the first step of histidine biosynthesis and is controlled via a complex allosteric mechanism where the regulatory protein HisZ enhances catalysis by the catalytic protein HisGS while mediating allosteric inhibition by histidine. Activation by HisZ was proposed to position HisGS Arg56 to stabilise departure of the pyrophosphate leaving group. Here we report