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Från år 2021 ska alla nybyggnationer i Europa vara nära-nollenergibyggnader. Detta innebär att byggnaders energianvändning bör vara låg och i mycket hög grad tillförs i form från förnybara energikällor som produceras på plats eller i närheten. Syftet med de höga energikraven är att påskynda takten för att skapa ett mer energieffektivt byggande. Den minskade energianvändningen tillsam-mans med en ö
Background: Over the past decade, the miniaturisation of animal borne tags such as geolocators and GPS-transmitters has revolutionized our knowledge of the whereabouts of migratory species. Novel light-weight multi-sensor loggers (1.4g), which harbour sensors for measuring ambient light intensity, atmospheric pressure, temperature and acceleration, were fixed to two long-distance migrant bird spec
This thesis deals with the general problem of controlling rigid-body systems through space, with a special focus on unmanned aerial vehicles (UAVs). Several promising UAV control algorithms have been developed over the past decades, enabling truly astounding feats of agility when combined with modern sensing technologies. However, these control algorithms typically come without global stability gu
Unstructured citizen-science data are increasingly used for analysing the abundance and distribution of species. Here we test the usefulness of such data to predict the seasonal distribution of migratory songbirds, and to analyse patterns of migratory connectivity. We used bird occurrence data from eBird, one of the largest global citizen science databases, to predict the year-round distribution o
Microsoft Word - General study plan_Medical Science, doctoral degree_2021_beslutad.doc Research Studies Board GENERAL STUDY PLAN FOR DOCTORAL STUDIES IN MEDICAL SCIENCE Scope: 240 credits Qualification: Degree of Doctor Approved on 11 June 2018 Revised on 10 December 2018. Applies from 1 January 2019 Revised on 3 December 2019. Applies from 1 January 2020 Revised on 17 December 2020. Applies from
Utredningsrapport - Sammanslagning av geologi, INES och CEC Page 1 of 40 Reg. No. STYR 2022/1317 Date 2022-11-14 Postal address Kansli N, Box 118, 221 00 Lund Visiting address Astronomy building, Sölvegatan 27 Telephone 046-222 7182, (switch) 046-222 00 00 E-mail: Tobias.Nilsson@science.lu.se Investigation of how research in the Department of Geology, the Department of Physical Geography and Ecosy
I denna rapport undersöks hur olika åtgärder påverkar trafiksituationen för oskyddade trafikanter i korsningar. Undersökningen görs främst utifrån de tre aspekterna trafiksäkerhet, framkomlighet och omgivande miljö. Arbetet omfattar sex korsningar i Helsingborg som har byggts om vid olika tidpunkter och där olika åtgärder har vidtagits. För att göra en bedömning av åtgärdernas påverkan på trafiksäThis report examines how different traffic improvement measures affect the traffic situation for vulnerable road users at intersections. The survey is conducted mainly based on the three categories of road safety, accessibility and the surroundings. The work investigates six intersections in Helsingborg that have been rebuilt at different times and where different measures have been taken. To eval
This work aimed to characterize single chain fragment variables (scFvs) against S100A7 and Calprotectin, proteins part of the Ca2+ binding S100 family that have been associated with inflammatory diseases and cancer. The mechanisms governing the physiological functions of S100 proteins are not fully understood, but it is known that many of them contribute to maintaining homeostasis in the intracell
PURPOSE: The R2Pulm trial was conducted to evaluate the effect of busulfan-melphalan high-dose chemotherapy with autologous stem-cell rescue (BuMel) without whole-lung irradiation (WLI) on event-free survival (main end point) and overall survival, compared with standard chemotherapy with WLI in Ewing sarcoma (ES) presenting with pulmonary and/or pleural metastases. METHODS: From 2000 to 2015, we e
Microstructure and crystallographic texture are the key factors that determine the properties of sputtering target used in integrated circuit fabrication. Multi-pass clock-rolling has been used recently to produce Ta sputtering targets. However, the effect of strain per pass, or the number of passes to achieve desired thickness, in clock-rolling on the homogeneity of final microstructure has not b
Accurately quantifying soil base cation pool sizes is essential to interpreting the sustainability of forest harvests from element mass-balance studies. The soil-exchangeable pool is classically viewed as the bank of "available" base cations in the soil, withdrawn upon by plant uptake and leaching and refilled by litter decomposition, atmospheric deposition and mineral weathering. The operational
Background: Informed consent is a prerequisite for patients included in clinical trials. Trial design, inclusion criteria and legal requirements are increasingly complex. This complexity challenges design and delivery of written and oral trial information to ensure understandable information. To evaluate the level of concordance between patients' and informing physicians' assessments regarding pat
1. Measurements of membrane capacitance, as an indicator of exocytosis, and intracellular Ca2+ concentration ([Ca2+]i) were used to determine the Ca2+ dependence of secretion in single pancreatic B-cells. 2. Exocytosis was dependent on a rise in [Ca2+]i and could be evoked by activation of voltage-dependent Ca2+ currents. The threshold for depolarization-induced release was 0.5 microM [Ca2+]i. Onc
Previous studies in the rat have shown that a serotonergic depletion greatly potentiates the learning and memory impairments produced by pharmacological or lesion-induced cholinergic blockade in the forebrain. The impairment produced by combined serotonergic-cholinergic lesions is reminiscent of that seen in memory-impaired aged rats. In the present experiment, we investigated whether grafts of ch
Background and ObjectivesIntestinal levodopa/carbidopa gel infusion (LCIG) is superior to oral treatment in advanced Parkinson disease. The primary objective of this trial was to investigate whether continuous subcutaneous or intravenous infusion with a continuously buffered acidic levodopa/carbidopa solution yields steady-state plasma concentrations of levodopa that are equivalent in magnitude, a
The maintenance of protein homeostasis, also referred to as proteostasis, is essential for preserving the structural and functional stability of the proteome in living organisms. This involves the precise control of protein synthesis, folding, and degradation. As proteostasis disruption can cause growth and survival deficiencies in bacteria, the investigation of proteostasis has rapidly emerged as
Optimization of Affibody molecules would allow for high contrast imaging of cancer associated surface receptors using molecular imaging. The primary aim of the thesis was to develop Affibody-based PET imaging agents to provide the highest possible sensitivity of RTK detection in vivo. The thesis evaluates the effect of radiolabelling chemistry on biodistribution and targeting properties of Affibod
Objectives To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk. Design Meta-analysis of genome wide association studies (GWAS) and a two-sample mendelian randomisation approach. Setting 25 cohorts from Europe, United States, east Asia, and Australia with genome wide genotyping and fracture data. Participants A discover
