Effect of Ganglioside GM3 on the Mobility and Mesostructure of Lipid and α-Synuclein Co-assemblies: A Combined Polarization Transfer Solid-State NMR and Scattering Study
The 13C mobility and cross-β-sheet structure of lipid-protein co-assemblies formed by incubating ganglioside GM3-containing model membranes with the amyloid protein α-synuclein were investigated by solid-state NMR and wide-angle X-ray scattering (WAXS) at varying lipid-to-protein ratios and membrane compositions at body temperature. The POPCGM3 model membrane was characterized by PT ssNMR and X-ra
