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Many group A streptococcal strains express two different immunoglobulin-binding proteins, encoded by closely linked genes: characterization of the proteins expressed by four strains of different M-type
Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q
Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i
Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis
Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe
Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome
INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w
Streptococcus pyogenes secreted enzymes interacting with the human host
Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that
Potentialities of manganese ore and iron-carbon particles for pharmaceuticals and personal care products removal in electroactive constructed wetland
This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo
Handkirurgi och dess specifika omvayrdnad
Handkirurgi och dess specifika omvårdnad U PP D R A G SU TB IL D N IN G Institutionen för hälsovetenskaper erbjuder utbildningar som genomförs av lärare vid Lunds universitet och i många fall i samarbete med arbetslivet - en garanti för både ämnesmässig bredd och aktualitet, ett vetenskapligt djup och en modern pedagogik. Institutionens uppdragsverksamhet sker i samarbete med Lund University Commi
https://www.medicin.lu.se/sites/medicin.lu.se/files/handkirurgi_och_dess_specifika_omvayrdnad.pdf - 2026-05-20
The Implementation of the Frequency-Time Encoded Decoy-State Protocol with the Slow-Light Effect for Quantum Memories
Since the dawn of the first civilizations, the security of information has proven vital to the success of any given community. History records the first attempts at using cryptography techniques in a 1900 BC to 600 BC time frame. In ancient times, the working mechanism of this technique involved the use of letters in the alphabet. To secure the information, these techniques shifted the letters’ nu
IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.
EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca
Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions
Countercurrent distribution of lymphocytes from human peripheral blood in an aqueous two-phase system. : II. Separation into subsets of lymphocytes with distinctive functions
Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti
Recurrent risk of hospitalization among older persons with problematic alcohol use: A multiple failure-time analysis with a discontinuous risk model
Background and AimsOlder persons with problematic alcohol use vary in psychosocial functioning, age of onset for problem drinking and use of other drugs. The study measured the differential risks of all-cause, alcohol, polydrug and psychiatric-related repeated hospitalizations among older persons with problematic alcohol use.DesignA linked register-based cohort study with discontinuous multiple-fa
Neurofutures: Promises and Perils of Neurotechnologies
27 maj 2026 09:00 till 13:00 | Workshop From invasive and non-invasive brain-computer interfaces to data privacy, governance models, and the impact on democracy and human dignity, the Pufendorf-Theme has examined how these technologies are reshaping our brains, bodies, and societies. Now, the researchers invite academic staff, students, practitioners, and curious minds - to join them for a provoca
https://www.lu.se/evenemang/neurofutures-promises-and-perils-neurotechnologies - 2026-05-20
Neurofutures: Promises and Perils of Neurotechnologies
27 maj 2026 09:00 till 13:00 | Workshop From invasive and non-invasive brain-computer interfaces to data privacy, governance models, and the impact on democracy and human dignity, the Pufendorf-Theme has examined how these technologies are reshaping our brains, bodies, and societies. Now, the researchers invite academic staff, students, practitioners, and curious minds - to join them for a provoca
https://www.psy.lu.se/evenemang/neurofutures-promises-and-perils-neurotechnologies - 2026-05-21
Neurofutures: Promises and Perils of Neurotechnologies
27 maj 2026 09:00 till 13:00 | Workshop From invasive and non-invasive brain-computer interfaces to data privacy, governance models, and the impact on democracy and human dignity, the Pufendorf-Theme has examined how these technologies are reshaping our brains, bodies, and societies. Now, the researchers invite academic staff, students, practitioners, and curious minds - to join them for a provoca
https://www.pi.lu.se/evenemang/neurofutures-promises-and-perils-neurotechnologies - 2026-05-21
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https://www.svet.lu.se/en/contact - 2026-05-21
2025 Spring meeting
The COMPUTE spring meeting 2025 will take place on Monday the 28th of April 2025. The theme is "Development of Scientific Software". The event is aimed atall who write code to do their research and want to become better at itall who use code to do their research and want to learn more about where this code comes from and how it might be improved.Program 9:45 - 10:15Fika before lecture room MH:Ries
https://www.compute.lu.se/other-activities/2025-spring-meeting - 2026-05-21
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Energy Storage & Conversion
Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r
https://www.energy.lth.se/research/energy-storage-conversion - 2026-05-21
