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Summary. This review describes the background for the development of recombinant FVIIa (rFVIIa; NovoSeven) for use in haemophilic patients with inhibitors. The first proof of principle for using pharmacological doses of FVIIa as a haemostatic agent was obtained by producing small amounts of pure plasma-derived FVIIa, which showed encouraging effect in two patients with haemophilia A and inhibitors
OBJECTIVE: To adapt the Knee injury and Osteoarthritis Outcome Score (KOOS) into French and to evaluate the psychometric properties of this new version. METHODS: The French version of the KOOS was developed according to cross-cultural guidelines by using the "translation-back translation" method to ensure content validity. KOOS data were then obtained in patients with symptomatic knee osteoarthrit
Microbial decomposition of soil organic matter (SOM) is the source of most of the terrestrial carbon dioxide emission. Consequently, our ability to predict how climate warming will affect the global carbon (C) budget relies on our understanding of the temperature relationship and adaptability of microbial processes. We exposed soil microcosms to temperatures between 0 and 54 degrees C for 2 months
BACKGROUND: Associations between cadmium (Cd) and kidney function have been reported even at low levels of exposure in the general population. Recently, the causality of these associations has been questioned. OBJECTIVES: We examined associations between urinary Cd (U-Cd; a biomarker of exposure) and urinary proteins that are used as biomarkers of kidney effects, based on repeated short-term sampl
BACKGROUND: Knowledge regarding characteristics and transmission of Neisseria gonorrhoeae, Chlamydia trachomatis and Mycoplasma genitalium and antibiotic resistance in N gonorrhoeae in Guinea-Bissau, West Africa, is entirely lacking. OBJECTIVES: To characterise N gonorrhoeae, C trachomatis and M genitalium samples from Guinea-Bissau and to define bacterial populations, possible transmission chains
Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on European subjects. Methods We performed a two-stage meta-analysis on more than 78 000 participants. In stage 1, we synthesised data from eight GWAS whereas data from 10 centres wer
AIMS/HYPOTHESIS: To date, the molecular function of most of the reported type 2 diabetes-associated loci remains unknown. The introduction or removal of cytosine-phosphate-guanine (CpG) dinucleotides, which are possible sites of DNA methylation, has been suggested as a potential mechanism through which single-nucleotide polymorphisms (SNPs) can affect gene function via epigenetics. The aim of this
Popular Abstract in Swedish Akupunktur är en mer än 2000 år gammal terapeutisk metod, som ingår i den traditionella kinesiska medicinen (TCM), för lindring av en del sjukdomar och symtom såsom smärta. Tunna, solida nålar instickes i så kallade akupunkturpunkter, oftast belägna i muskulaturen och utspridda över hela kroppen längs linjer som kallas meridianer. Det finns ett flertal olika sätt att teIn a retrospective follow-up study, n=202, long-term pain relief (>6 months) after a course of acupuncture treatments was found mainly among patients with chronic nociceptive pain while patients with neurogenic or psychogenic pain did not benefit much. In a placebo-controlled randomised single-blind long-term study with independent observer of chronic nociceptive low back pain, n=50, it was found
Wetland creation at large, regional scales is implemented as a measure to abate the biodiversity loss in agricultural landscapes and the eutrophication of watersheds and coastal areas by non-point source nutrient pollution (mainly nitrogen). The consequences of creating many new wetlands for biodiversity conservation and nutrient retention (ecosystem functioning) in agricultural landscapes are sti
Popular Abstract in Swedish Kostfiber visar på gynnsamma effekter på blodsockersvar, inflammationsmarkörer och blodfetter utifrån tre humanstudier som genomfördes i detta arbete. I en av studierna analyserades blod och urin med metabolomik. Det är en metod där man analyserar alla små molekyler (metaboliter) som finns i provet med hjälp av vätskekromatografi kopplat till masspektrometri. Med hjälp It is well-known that dietary fibre can have a positive effect on the development of lifestyle-dependent diseases such as cardiovascular disease and type 2 diabetes. However, the effect may be different for different kinds of fibre and different sub-populations at risk. Therefore, the effects of three different kinds of fibre on postprandial and long-term response in healthy subjects were investig
This work presents a comparative luminescence study of Pr3+ doped phase-pure BaLuF5 and mixed-phase BaLu2F8 – BaLuF5 materials synthesized via a hydrothermal route. The spectroscopic studies were mainly performed for phase-pure BaLuF5 and two mixed-phase materials, which, according to structural and phase compositional analysis, contained 90 or 70 wt% of orthorhombic BaLu2F8 and 10 or 30 wt% of cu
BACKGROUND: The cross-sectional association between cerebral tissue oxygen saturation (SctO 2) and heart failure (HF) has been previously studied, but the prognostic significance of SctO 2 in HF remains uncertain. This study aimed to assess the role of SctO 2 as a risk factor for all-cause mortality and rehospitalisation, as well as to explore the cross-sectional association between physical activ
Numerical models of meteorite delivery from impacts on the Moon have demonstrated that the impact event forming the lunar crater Tycho (~85 km diameter; ca. 109 Ma age) would have delivered considerable amounts of ejected material to Earth. The ejecta, containing lunar Ti- and V-rich chrome spinels, would have been distributed globally and admixed with seafloor sediments over a few meters of a typ
Importance Women with adverse pregnancy outcomes have higher subsequent cardiovascular risks, but their long-term risk of atrial fibrillation (AF) and potential causality are unclear. A better understanding of such risks is needed to identify women with high risk early in life and guide interventions to prevent AF and its complications. Objective To determine long-term risks of AF associated with
Pay policy programme for Lund University.Word Page 1 of 8 Dnr I F 9 5307/1999 Pay policy programme for Lund University approved by the University Board on 7 April 2000 The basic aim of the pay policy is to help the University in achieving its targets. Motivated, committed and knowledgeable employees are a necessary prerequisite for high quality in the University’s activities. Lund University shall
https://www.staff.lu.se/sites/staff.lu.se/files/2023-10/pay-policy-programme-for-Lund-University.pdf - 2026-05-10
An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood An Age-Related Exponential Decline in theRiskofMultiple Islet Autoantibody Seroconversion During Childhood https://doi.org/10.2337/dc20-2122 OBJECTIVE Islet autoimmunity develops before clinical type 1 diabetes and includes multiple and single autoantibody phenotypes. The objective was to
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/127_MP237_Bonifacio_Diab%20Care_2021.pdf - 2026-05-10
Handledare: Hervé Corvellec VT 2011 Kandidatuppsats Institutionen för Service Management Food Service Management INTERN KOMMUNIKATION för att verkställa ett avtal inom avfallssektorn Rosanna Lindström Kristina Nilsson Sara Nilsson Intern kommunikation | Lunds universitet 2 Förord Detta är vårt examensarbete som beskriver hur ett avtal inom avfallssektorn verkställs med hjälp av intern kommunikatio
https://www.ses.lu.se/sites/ses.lu.se/files/oki-rosanna_lindstroem_kristina_nilsson_sara_nilsson.pdf - 2026-05-10
NORCA POLICY BRIEF - 2 (v2.0) POLCA (project number 101228676), funded by the European Commission under Horizon Europe MSCA Staff Exchanges programme From Service Digitisation to Digital Governance: Lessons from Scandinavia for Uzbekistan POLICY BRIEF MARCH 2026 KEY MESSAGES Uzbekistan has made rapid progress in digitalising public services. More than 770 public services are now available through
https://www.norca.lu.se/sites/norca.lu.se/files/2026-03/NORCA%20POLICY%20BRIEF%20-%202%20(v2.0).pdf - 2026-05-10
Embedded 3D Printing in Self‐Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs RESEARCH ARTICLE www.advancedscience.com Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs Janko Kajtez,* Milan Finn Wesseler, Marcella Birtele, Farinaz Riyahi Khorasgani, Daniella Rylander Ot
Yttrande för remissen: Förbättrade möjligheter för barn att utkräva sina rättigheter enligt barnkonventionen SOU 2023:40 Sida 1 av 4 Dekan REMISSYTTRANDE Diarienummer V 2023/2523 Datum 2024-01-29 Rektor Yttrande för remissen: Förbättrade möjligheter för barn att utkräva sina rättigheter enligt barnkonventionen SOU 2023:40 Samhällsvetenskapliga fakulteten vid Lunds universitet, som anmodats att ytt
