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The first paper, Pharmaceutical R&D: a real option approach, considers the process of pharmaceutical R&D analyzed with real option theory. This process is analyzed as an opportunity to research and develop a new pharmaceutical. Contrary to other models using real option analysis I use an option that takes time to exercise. Thus, the important aspect of long R&D processes when developin
Superporous agarose beads were used as a support for hydrophobic interaction chromatography. These beads have large connecting flow pores in addition to their normal diffusion pores. The flow pores, which are approximately one fifth of the overall diameter of the superporous agarose beads, were earlier shown to give the beads improved mass transfer properties relative to homogeneous agarose beads
Purpose: Studies of desmopressin in children with primary nocturnal enuresis show a greater than 90% decrease in wet nights in 20% to 30%, a 50% to less than 90% decrease in 20% to 40% and less than a 50% decrease in up to 60%. Insufficient response to desmopressin is attributable to various factors, including differences in the primary nocturnal enuresis definition, underlying bladder dysfunction
Aim: The Driving to Learn project focused on people with profound cognitive disabilities and their possible achievements from practicing joystick-use in a powered wheelchair. The aim of this study within the project was to statistically analyse the participants' outcomes, and to explore factors, in terms of participant and training characteristics, associated with a favourable outcome of training
The incidence of Hodgkin lymphoma has increased among adolescents and young adults in recent decades, but the relevant risk factors in early life are still unknown. A national cohort study was conducted of 3,571,574 individuals born in Sweden in 19732008 and followed up for Hodgkin lymphoma incidence through 2009, to examine perinatal and family risk factors for Hodgkin lymphoma in childhood throu
The pathogenesis of pulmonary fibrosis is a complicated chain of interactions between cells and molecules. During recent years bronchoalveolar lavage (BAL) in patients with various interstitial lung disorders has increased our knowledge of the fibrosis process and focused on new interesting interactions. Here we present an animal model which makes it possible to apply both morphological and immuno
Stimulation around the superior cerebellar peduncle or within the deep cerebellar nuclei is known to inhibit the inferior olive with a very long latency. It has been suggested that this inhibition is mediated by the GABA-ergic nucleo-olivary pathway, but alternative explanations such as activation of an indirect excitatory pathway or a pathway via the red nucleus are possible. A long-latency inhib
Hemicelluloses, which are abundant in nature and have potential use in a wide variety of applications, may make an important contribution in helping relieve society of its dependence on petrochemicals. However, cost-efficient methods for the isolation of hemicelluloses are required. This article presents an economic evaluation of a full-scale process to isolate hemicelluloses from process water fr
The present series comprises all families (n = 77) with haemophilia B in Sweden and may be considered to be representative for the purposes of a population-based study of mutational heterogeneity. The 77 families (38 severe, 10 moderate, 29 mild) had 51 different mutations in total. Thirteen families had total, partial or small deletions, two had mutations in the promoter, eight families had splic
Here, we describe the preparation, structure, and properties of cryogel sponges, which represent a new type of macroporous biomaterial for tissue engineering. Cryogels were produced through freeze-thawing techniques, either from agarose alone or from agarose with grafted gelatin. The aim of this study was to evaluate agarose cryogel sponges as scaffolds for Culturing both isolated pancreatic islet
Objectives: To compare a laparoscopic (totally extraperitoneal patch (TEP)) and an open technique (Lichtenstein) for inguinal hernia repair regarding recurrence rate and possible risk factors for recurrence. Summary Background Data: Laparoscopic hernia repair has been introduced as an alternative to open repair. Short-term follow-tip suggests benefits for those patients operated with a laparoscopi
Patients with anaplastic thyroid carcinoma can rarely be cured, but every effort should be made to prevent death due to suffocation. Between 1984 and 1999, 55 consecutive patients with anaplastic thyroid carcinoma were prospectively treated according to a combined regimen consisting of hyperfractionated radiotherapy, doxorubicin, and when feasible surgery. Radiotherapy was carried out for 5 days a
As climate change have become generally accepted as a potential problem, reducing the greenhouse gas emissions and global energy demand has become an important research topic. This have led to an increased interest towards the retrofitting of the existing building stock, including cultural protected buildings. Due to the cultural protection, carrying out major alteration such as exterior wall retr
LTH:s 13:e Pedagogiska Inspirationskonferens, 4 december 2025 Is LTH keeping up with the AI revolution? Sergio Davila Martinez, Leandro Iannacone, Viktor Jönsson, Erik Ottosson, Taqwa Saeed, LTH Abstract—Our objective is to identify how LTH teachers are adapting their teaching to the rise of generative AI tools. We conducted a survey targeting course coordinators at LTH to assess their opinions o
https://www.lth.se/fileadmin/cee/genombrottet/konferens2025/B1_Martinez_etal.pdf - 2026-05-31
Betong skadas ibland av frysning. I miljöer där dessutom salt förekommer blir det särskilt svårt för betongen att inte skadas. Skadorna yttrar sig som avskalningar på betongens yta, men den inre strukturen kan vara opåverkad. Utöver den estetiska oangelägenheten kan dessa ytliga avskalningar även bidra till påskyndade korrosionskador och inre frostskador. Syftet med detta examensarbete är att undeConcrete is sometimes damaged by freezing. The damage increases if salt also is present. The damage consists of the removal of small flakes on the surface of the concrete, the inner structure may however be completely unaffected. This surface damage may increase the degree of saturation and ingress of e.g. chloride ions, which may lead to inner frost damage and corrosion on the reinforcing steel.
Eventuella beteendemässiga konsekvenser av pornografianvändande har undersökts flitigt under de senaste decennierna. Forskningen har dock inte inkorporerat kontextuella aspekter av pornografianvändande eller intresserat sig för möjliga samband med användarnas egen sexualitet. Denna studies första syfte var att undersöka pornografianvändande i en icke-klinisk population av 16- till 30-åringar i Sve
Recent surveys show that on average about 70% of the area budget of the system on chip (SoC) is occupied by Static Random Access Memory (SRAM)s, with a capacity ranging from a few kilo-bits to tens of megabits. SRAM (static RAM or SRAM) is a type of electronic memory that uses bistable latching circuitry (flip-flop) to store each bit. SRAM is volatile in the conventional sense that data is eventua
Uppsatsens syfte är att fördjupa förståelsen för den svenska lagstiftarens avvägning mellan personlig integritet och de brottsbekämpande myndigheternas behov av datalagring hos telekommunikationsbolag. Den nationella rätten styrs av EU-rätt på det här området och därför ingår i syftet att redogöra för det nationella och EU-rättsliga regelverket rörande dels datalagring av brottsbekämpande skäl, deThis thesis aims at providing an in-depth study of the balancing act made by the Swedish legislator between the rights to privacy and data protection on the one hand, and the retention of data generated in connection with the provision of publicly available electronic communications networks on the other hand. The latter aspect is something that is made in order to ensure that the data are availab
