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Pathologic aggregation of beta-amyloid (A beta) peptide and the axonal microtubule-associated protein tau protein are hallmarks of Alzheimer's disease (AD). Evidence supports that A beta peptide accumulation precedes microtubule-related pathology, although the link between A beta and tau remains unclear. We previously provided evidence for early co-localization of A beta 42 peptides and hyperphosp
Vector navigation, i.e., maintaining a constant heading for a given amount of time, is hypothesized to provide a viable basis for the navigational feats of a number of long-distance animal migrants. Since animals following this strategy are subject to drift by wind or by ocean current, performing long migrations relying on vector navigation is particularly challenging. We tested whether vector nav
The Paleocene-Eocene Thermal Maximum (PETM, ca. 56 Ma) is marked by a negative carbon isotope excursion (CIE) and increased global temperatures. The CIE is thought to result from the release of 13C-depleted carbon, although the source(s) of carbon and triggers for its release, its rate of release, and the mechanisms by which the Earth system recovered are all debated. Many of the proposed mechanis
The natural products pulchrol and pulchral, isolated from the roots of the Mexican plant Bourreria pulchra, have previously been shown to possess an antiparasitic activity toward Trypanosoma cruzi, Leishmania braziliensis and L. amazonensis, protozoa responsible for the Chagas disease and leishmaniasis. These infections have been classified as neglected diseases, and still require the development
Background: The Hawthorne Effect is the change in behaviour by subjects due to their awareness of being observed and is evident in both research and clinical settings as a result of various forms of observation. When the Hawthorne effect exists, it is short-lived, and likely leads to increased productivity, compliance, or adherence to standard protocols. This study is a qualitative component of an
Insects contribute considerably to global crop pollination, with pollination deficits being documented for multiple entomophilous or pollinator-dependent crops. Different cultivars of crops are being cultivated within and across production regions, so it is essential to understand the cultivar variability of pollination deficits. Here, we used a dataset from 286 sites from multiple production regi
Reliable quantitative vegetation reconstructions for Europe during the Holocene are crucial to improving our understanding of landscape dynamics, making it possible to assess the past effects of environmental variables and land-use change on ecosystems and biodiversity, and mitigating their effects in the future. We present here the most spatially extensive and temporally continuous pollen-based r
Accurate and continuous monitoring of inland surface water dynamics is vital for sustainable water resource management, climate impact assessment, and ecological planning. This study introduces a machine learning-based remote sensing-based data-fusion framework that improves Sentinel-3 radar altimeter (SRAL) estimations of water surface elevation (WSE) by integrating ERA5 reanalysis climate varia
Human dihydroorotate dehydrogenase (DHODH) catalyzes the fourth step of the de novo pyrimidine biosynthesis pathway and uses ubiquinone Q10, a lipophilic molecule located in the inner mitochondrial membrane (IMM), as its co-substrate. DHODH is anchored to the IMM by a single transmembrane helix located at its N-terminus. Nevertheless, how DHODH function is determined by its surrounding membrane en
Background: One of the preanalytical factors that can affect the results of arterial blood gas (ABG) analysis is the time from sample collection to analysis. A delay in analysis may affect the results due to factors such as ongoing cellular metabolism within the blood sample, gas exchange between the blood sample and the environment, and temperature changes. ABG analysis can be delayed for various
Nitrogenase is the only enzyme that can cleave the strong triple bond in N2, making nitrogen available for biological life. There are three isozymes of nitrogenase, differing in the composition of the active site, viz., Mo, V, and Fe-nitrogenase. Recently, the first crystal structure of Fe-nitrogenase was presented. We have performed the first combined quantum mechanical and molecular mechanical (
Prostate-specific antigen (PSA) is a serine protease secreted by hath normal prostate glandular celts and prostate cancer cells. The major proteolytic substrates for PSA are the gel-forming proteins in semen, semenogelin (Sg) I and II. On the basis of the PSA cleavage map for Sg I and II, a series of small peptides (ie., ≤ 7 amino acids) was synthesized and coupled at the COOH terminus to 7-amino-
Pedestrians and cyclists are so-called unprotected road users which are sensitive in the context of road safety. When it comes to road safety focus are often placed on pedestrians-cars and cyclist-cars, in this report focus are placed on the road safety between pedestrians and cyclists. Pedestrians and cyclists are often referred to a combined space, with or without a separation. The purpose of th
The thesis consists of a description of the waste management in Sweden today, related to a case study at IKEA’s warehouses in Älmhult. Waste is globally one of the most important environmental challenges. Waste management in Sweden has developed a lot during the past years and is now standing in front of the next big challenge: to reach higher up in the waste hierarchy. By studying the academic li
Som student vid Lunds universitet kan du ladda ner olika program som hjälper dig i dina studier. Här hittar du information om hur du får tillgång till och installerar dessa program. Microsoft Office 365 UniversityMed ditt studentkonto kan du logga in på Microsofts portal och ladda ner bland annat:WordExcelPowerPointOneNoteOutlook.Du får även tillgång till Microsoft Teams och 30 GB lagringsyta på O
https://www.lu.se/student/it-tjanster-och-studentsupport/programvara - 2026-07-20
HRS4R Form | EURAXESS Internal Review Case number: 2019SE450153 Name Organisation under review: Lund University, Lund, Sweden Organisation’s contact details: Kajsa Roubert, LDC, kajsa.roubert@ldc.lu.se 1. Organisational Information Please provide an update of the key figures for your organisation. Figures marked * are compulsory. STAFF & STUDENTS FTE (December 2021) Total researchers = staff, fell
This thesis delves into small business administration and scheduling through interviews with two different types of businesses within the service sector. A nightclub and an inn. As part of the project, a prototype with the basic functionalities has been developed. An analysis is made of the strengths and weaknesses of different administration and scheduling techniques and an explanation is given o
For centuries, people have appreciated the taste of wild mushrooms which can be found in nature throughout the European continent and the Fennoscandian peninsula. This is especially so for those of the order of Cantharellales, where you find the Golden Chanterelle among others. Today the commercial aspect of mushroom harvesting has resulted in regulations and guidelines set out by the Nordic Counc
Popular Abstract in Swedish Antalet äldre i befolkningen ökar i förhållande till andra åldersgrupper. Detta beskrivs medföra en ekonomisk utmaning för samhället och att fler äldre behöver skjuta upp sin ålderspension. Avhandlingen bygger på fyra studier med det övergripande syftet att bidra till ökad kunskap om faktorer som medverkar till ett förlängt alternativt förkortat arbetsliv bland personerIn most of the industrialised world, the proportion of older and retired people in the population is continuously increasing. This will have budgetary implications for maintaining the welfare state, because the active working section of the population must fund the non-active and old population. Aim: The overall aim of this thesis was to obtain knowledge about older workers’ work and life situatio
Spectral aerosol light absorption is an important parameter for the assessment of the radiation budget of the atmosphere. Although on-line measurement techniques for aerosol light absorption, such as the Aethalometer and the Particle Soot Absorption Photometer (PSAP), have been available for two decades, they are limited in accuracy and spectral resolution because of the need to deposit the aeroso
