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The cardiac troponin T variations have often been used as an example of the application of clinical genotyping for prognostication and risk stratification measures for the management of patients with a family history of sudden cardiac death or familial cardiomyopathy. Given the disparity in patient outcomes and therapy options, we investigated the impact of variations on the intermolecular interac

BACKGROUND: Early life risk factors are associated with cardiometabolic disease, but have not been fully studied in atrial fibrillation (AF). There are discordant results from existing studies of birth weight and AF, and the impact of maternal body size, gestational age, placental size, and birth length is unknown.METHODS AND RESULTS: The Helsinki Birth Cohort Study includes 13 345 people born as

Neural transplantation is developing into a therapeutic alternative in Parkinson's disease. A major limiting factor is that only 3-20% of grafted dopamine neurons survive the procedure. Recent advances regarding how and when the neurons die indicate that events preceding actual tissue implantation and during the first week thereafter are crucial, and that apoptosis plays a pivotal role. Triggers t

Signal transduction in response to growth factors is a strictly controlled process with networks of feedback systems, highly selective interactions and finely tuned on-and-off switches. In the context of cancer, detailed signaling studies have resulted in the development of some of the most frequently used means of therapy, with several well established examples such as the small molecule inhibito

The purpose of this study is to analyse the communication of Apple to illustrate how social exclusion is used to produce fear, and how it has played the role as a means of persuasion in a constructed reality. In the present investigation process the researchers have taken a critical stance. The authors aim at unveiling the structure of implicit means of persuasion in various Apple’s campaigns over

Enligt Newsecs rapport från 2016 söker företag idag kontor som har effektiv kontorsyta med stor flexibilitet vad det gäller både area och hyresavtal. Deras analys är att sådana kontor kommer fortsätta att efterfrågas. Vad som menas med flexibla hyresavtal är inget som är självklart i branschen men i detta examensarbete innebär sådana hyresavtal kortare hyrestider och mindre ytor för varje aktör soAccording to Newsec's report from 2016 companies are looking for offices that have efficient office space with great flexibility in terms of both area and lease. Their analysis is that such offices will continue to be demanded. What is meant by flexible real estate leases is nothing that is obvious in the industry but in this paper such leases mean less lease times and less space for each part

Som följd av klimatförändringar kommer klimatanpassningsåtgärder att bli nödvändiga för att skydda mot effekterna av det förändrade klimatet. Det förändrade klimatet kommer innebära att risken för översvämningar och erosion ökar längs med Sveriges kuster, sjöar och vattendrag. Vem det är som bär ansvaret för att se till att dessa klimatanpassningsåtgärder kommer till stånd råder det en osäkerhet kAs a result of climate change, our society will need to start to adapt to the changing conditions. With these changes the risk of floods, races, spills and erosion along the coasts, lakes and streams of Sweden will increase. The need to take action to counteract these impending risks is strong but how is going to take responsibility for these actions? The purpose of the report is to investigate th

Astronomiska observationer på 1900-talet visade att det saknas lysande materia i vårt universum. Materian som inte syntes fick namnet mörk materia. Efter denna upptäckt har olika teoretiska modeller och experiment skapats för att förklara mörk materias egenskaper. På CERN sker forskning för att upptäcka mörk materia i ATLAS detektorn. Simuleringar av sådana händelser har blivit undersökta i detta Standard matter, the matter that we can see, only make up about 6% of the universe. Astronomical observations have found that there exist other matter, which is non-luminous, called dark matter. This matter can interact gravitationally with standard matter, but it is unknown if it can interact weakly with the help of some other force as well. If such interactions were possible, events between dark

The consumption and production of livestock have a negative impact on the environment and climate. In many Western countries, the consumption is particularly high and it is expected to increase globally. This increase will lead to further pressure on already stressed planetary boundaries. Recently edible insects have been proposed to be an alternative to conventional meat, because they have a lowe

Informationssamhället medför många frågor beträffande om hur rätten till personlig integritet ska balanseras med rätten till informations- och yttrandefrihet, vilket den nya dataskyddsförordningen (DSF) inte ännu gett många svar på. I den här uppsatsen undersöker jag fenomenet med personuppgiftsregister, innehållande information hämtad från allmänna handlingar, publicerade på internet för kommersiThe information society brings many questions in terms of how personal integrity is to be balanced with the freedom of expression and information, which the General Data Protection Regulation (GDPR) has not yet provided many answers to. In this thesis, the phenomena with websites containing personal data, obtained from official documents, published on the Internet for commercial purposes, is exami

In multi-user multiple input multiple output (MU-MIMO), the complexity of the base-station scheduler has increased further compared to single-user multiple input multiple output (SU-MIMO). The scheduler must understand if several users can be spatially multiplexed in the same time-frequency resource. One way to spatially separate users is through beamforming with sufficiently many antennas. In thi

Green energy defaults (where the uptake of renewable energy is promoted among households by opt-out tariffs) are gaining increasing interest with policy makers, due to the high enrolment rates shown in (experimental) studies. Such default choices are often justified on normative and behavioural grounds as although consumers express a desire and willingness to pay for green energy, they often fail

With growing awareness about their environmental impact, music festivals have increased their efforts to become greener since the 2000s. In line with this trend, the German Fuchsbau Festival developed a transport plan, taking into account that up to 80.0% of a festival’s emissions are produced through audience travel. Aiming at triggering a greener travel behaviour among its visitors, four measure

With the ever increasing demand for higher data rates and reliability, efficient management of cellular networks remains a challenge. Among other technologies, fifth generation systems are expected to tackle this challenge using large electronically controllable antenna arrays operating in the time division duplex mode. In such systems, spatial beamforming is implemented with accurate channel esti

Purpose: The purpose and aim with this research was to understand how brands successfully can co-opt a social movement; specifically feminism, as part of their brand building-strategies. The phenomenon was explored by comparing one successful case, Libresse’s ‘RedFit’ campaign, with a relatively the less successful case; that is, H&M’s ‘Ladylike’ campaign. Methodology: This study takes a rela

Formerly widely distributed throughout Europe, the great snipe (Gallinago media) – a medium-sized wader species – has experienced an important decline in the last century, mainly driven by habitat loss. Remaining population are now restricted to eastern Europe and Scandinavia and the species is considered endangered. The great snipe (Gallinago media) is a food specialist, feeding almost exclusivel

The purpose of this study is to improve the understanding of the ability of educational interventions to improve strategic thinking. It does this both by contributing to the available empirical data on the development of strategic thinking ability and by exploring potential; avenues of research, intervention designs, study designs, sampling issues and analysis problems, for future studies as part

Purpose: The purpose of this thesis is to examine the impact of diverse boards with one, two, three or more women in limited companies founded in Sweden in 2010 on financial performance. Firm’s characteristics as board’s gender distribution, net sales, ROE, board size and number of employees will be examined aiming to understand how these boards are composed in terms of gender diversity and the im