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IDAC-Bio, A Software for Internal Dosimetry Based on the New ICRP Biokinetic Models and Specific Absorbed Fractions

ABSTRACT: Radiation dosimetry is central to virtually all radiation safety applications, optimization, and research. It relates to various individuals and population groups and to miscellaneous exposure situations-including planned, existing, and emergency situations. The International Commission on Radiological Protection (ICRP) has developed a new computational framework for internal dose estima

Benign prostatic hyperplasia/obstruction ameliorated using a soluble guanylate cyclase activator

Benign prostatic hyperplasia (BPH) is a feature of ageing males. Up to half demonstrate bladder outlet obstruction (BOO) with associated lower urinary tract symptoms (LUTS) including bladder overactivity. Current therapies to reduce obstruction, such as α1-adrenoceptor antagonists and 5α-reductase inhibitors, are not effective in all patients. The phosphodiesterase-5 inhibitor (PDE5I) tadalafil is

Localization using Distance Geometry : Minimal Solvers and Robust Methods for Sensor Network Self-Calibration

In this thesis, we focus on the problem of estimating receiver and sender node positions given some form of distance measurements between them. This kind of localization problem has several applications, e.g., global and indoor positioning, sensor network calibration, molecular conformations, data visualization, graph embedding, and robot kinematics. More concretely, this thesis makes contribution

100 miljoner ord : Reflektioner kring forskningsarbete med storskaliga dataset som historisk empiri

I forskningsprojektet Välfärdsstaten analyserad (1945–89) arbetar vi med olika typer av algoritmisk textanalys av storskalig empiri från politikens sfär (digitaliserat riksdagstryck och statliga offentliga utredningar under perioden), dagspress och skönlitteratur. Svensk efterkrigstid är en väl utforskad period, men genom att applicera digitala metoder på kurerade dataset kan politikens, nyhetsmedA hundred million words: Reflections on historical research with large-scale textual datasets as empirical evidenceThe research project Welfare State Analytics: Text Mining and Modelling Swedish Politics, Media & Culture, 1945–1989 uses probabilistic methods and text-mining models to study three massive textual datasets from Swedish politics, news media, and literary culture. By topic modellin

Navigating the Minefield : Women's Experiences of Abortion in a Country with a Conscience Clause—The Case of Croatia

Many countries around the world have a conscience clause allowing physicians and health care providers to opt-out of performing abortions. This practice of conscientious objection to abortion care affects both healthcare providers and women's access to abortion care. In Croatia, a conscience clause was introduced in 2003. Nonetheless, women's experiences of abortion after the introduction have not

Informal care provision among male and female working carers : Findings from a Swedish national survey

INTRODUCTION: Informal carers in paid employment-working carers (WKCs)-have complex support needs. However, little is known about WKCs' pattern of informal care provision, the support they receive, the impact providing care has on their employment, and how these vary between male and female WKCs. This study describes the pattern of informal care provision and received support among Swedish WKCs.RE

Registry-based outcome assessment in haemophilia : a scoping study to explore the available evidence

Haemophilia is a congenital disorder with bleeding episodes as its primary symptom. These episodes can result in negative outcomes including joint damage, loss of active days due to hospitalization and reduced quality of life. Effective treatment, however, can improve the outcome. Registries have been used as a valuable source of information regarding the monitoring of treatment and outcome. The t

Time-lapse seismic analysis of pressure depletion in the Southern Gas Basin

In the Southern Gas Basin (SGB) of the North Sea there are many mature gas fields where time-lapse monitoring could be very beneficial in extending production life. However, the conditions are not immediately attractive for time-lapse seismic assessment. This is primarily because the main production effect to be assessed is a pore pressure reduction and frame stiffening because of gas production i

Flytta eller stanna? : Betydelsen av plats och platsförankring för den kvalificerade arbetskraftens internationella migration

Popular AbstractI takt med att svenska företag har ökat sina utlandssatsningar med bland annat direktinvesteringar på utländska marknader har också efterfrågan av internationell rörlighet bland den svenska kvalificerade arbetskraften ökat. En del av detta behov rör tidsbegränsade utlandsposteringar av svensk arbetskraft på så kallade ’expats-kontrakt’. Ofta utgår samhällsdebatten från en uppfattniAs Swedish companies have increased their commitments abroad, the demand for internationally mobile skilled Swedish labour has increased. Some of this demand concerns temporary positions on so called ’expats-contracts’. Often the discussion on this issue originates from a discourse that claims this type of labour force to be unanimously positive towards moving abroad to work. International tempora

Emerging challenges in antimicrobial resistance : implications for pathogenic microorganisms, novel antibiotics, and their impact on sustainability

Overuse of antibiotics is accelerating the antimicrobial resistance among pathogenic microbes which is a growing public health challenge at the global level. Higher resistance causes severe infections, high complications, longer stays at hospitals and even increased mortality rates. Antimicrobial resistance (AMR) has a significant impact on national economies and their health systems, as it affect

Storsjöodjuret i ett kalejdoskop. Humanekologiska perspektiv på en svensk kryptid.

"Storsjöodjuret”, eller “The Great Lake Monster”, är ett undflyende fenomen i sjön Storsjön, belägen i landskapet Jämtland i norra Sverige. Denna avhandling i ämnet humanekologi undersöker hur det sammankopplingar av det sociala, det kulturella, det historiska och det lokala påverkar formandet av detta svenska kryptid, eller “dolda djur”. Syftet med studien är att visa hur detta vetenskapligt ännuStorsjöodjuret, or The Great Lake Monster, is an elusive phenomenon in lake Storsjön, situated in the province of Jämtland in Northern Sweden. This dissertation in Human Ecology investigates how the intricate web of the social, the cultural, the historical, and the local influence the shaping of this Swedish cryptid, or “hidden animal”. The purpose of the study is to demonstrate how this scientifi

The frequency of atrial fibrillatory waves is modulated by the spatiotemporal pattern of acetylcholine release : a 3D computational study

In atrial fibrillation (AF), the ECG P-wave, which represents atrial depolarization, is replaced with chaotic and irregular fibrillation waves (f waves). The f-wave frequency, F f, shows significant variations over time. Cardiorespiratory interactions regulated by the autonomic nervous system have been suggested to play a role in such variations. We conducted a simulation study to test whether t

Late Pleistocene glacial history of Jameson Land, central East Greenland, derived from cosmogenic (10)Be and (26)Al exposure dating

Abstract in Undetermined Previous work has presented contrasting views of the last glaciation on Jameson Land, central East Greenland, and still there is debate about whether the area was: (i) ice-free, (ii) covered with a local non-erosive ice cap(s), or (iii) overridden by the Greenland Ice Sheet during the Last Glacial Maximum (LGM). Here, we use cosmogenic exposure ages from erratics to reconc

Heterologous expression of barley and wheat oxalate oxidase in an E-coli trxB gor double mutant

Oxalate oxidase catalyses the degradation of oxalic acid to carbon dioxide and hydrogen peroxide and is of commercial importance for clinical analyses of oxalate in biological samples. Novel potential applications for oxalate oxidase include the prevention of the formation of calcium oxalate incrusts in pulp and paper manufacture and rapid determination of oxalic acid in process waters. The potent

En artificiellt intelligent inre marknad: En analys av den föreslagna AI-förordningen och dess betydelse för säkerställandet av en väl fungerande inre marknad för AI

Under de senaste åren har det skett betydande framsteg inom teknikområdet artificiell intelligens (AI). AI är ett komplext tekniskt område som involverar utveckling av mjuk- och programvara med förmåga att efterlikna de kognitiva egenskaper som normalt associeras med människor. Teknikutvecklingen på området förväntas föra med sig stora ekonomiska och sociala fördelar, men är också förenad med riskIn recent years, significant technological advancements have been made in the field of artificial intelligence (AI). AI is a complex technical domain that involves the development of software and hardware capable of mimicking the cognitive abilities normally associated with humans. Technological advancements in AI are expected to bring about substantial economic and social benefits. However, these

Hur främjas skapandet av sociala nyttor i campus utemiljöer?

Behovet av att skapa hållbara och flexibla byggnader har vuxit under de senaste åren, inte minst för att möta högt uppsatta klimatmål. Utrymmena mellan byggnaderna, med andra ord utemiljöer, har regelbundet prioriterats sekundärt och anpassats i stor utsträckning efter det bebyggda behovet. Utemiljöer i urban kontext innehåller ofta mer eller mindre kollektiva varor, som är icke-exkluderbara och i

Prospective Seroepidemiologic Study of Human Papillomavirus and Other Risk Factors in Cervical Cancer

Background: Several sexually transmitted infections (STI) have been reported to interact with human papillomavirus (HPV) in the etiology of cervical cancer. A large cohort study is required to obtain a both unbiased and stable estimate of their effects. Methods: Four major biobanks in the Nordic Countries containing samples from about 1,000,000 subjects were linked with nation-wide cancer registri

Experimental demonstration of efficient and selective population transfer and qubit distillation in a rare-earth-metal-ion-doped crystal

In optically controlled quantum computers it may be favorable to address different qubits using light with different frequencies, since the optical diffraction does not then limit the distance between qubits. Using qubits that are close to each other enables qubit-qubit interactions and gate operations that are strong and fast in comparison to qubit-environment interactions and decoherence rates.