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Michelson interferometers have been routinely used in various applications ranging from testing optical components to interferometric time-resolved spectroscopy measurements. Traditionally, plate beamsplitters are employed to redistribute radiation between the two arms of an interferometer. However, such an interferometer is susceptible to relative phase fluctuations between the two arms resulting
We study space complexity and time-space trade-offs with a focus not on peak memory usage but on overall memory consumption throughout the computation. Such a cumulative space measure was introduced for the computational model of parallel black pebbling by [Alwen and Serbinenko 2015] as a tool for obtaining results in cryptography. We consider instead the nondeterministic black-white pebble game a
This open access book adopts a rights-based approach to shed light on the different legal and policy instruments that have been developed to implement circular migration policies in the EU, and their consequences for the rights of migrant workers. It contributes to the understanding of the meaning of this concept in general and in the EU, as well as specifically regarding its Eastern neighborhood.
Aim: The aim of this study was to interpret and understand the meanings of the lived experiences of visiting of patients in an ICU and their families. Method: The research design was hermeneutic, based on interviews. This study includes 12 interviews with seven patients and five relatives who had been in an ICU. The interview text was interpreted in a Gadamerian manner as different plays with acto
At the Rio Earth Summit of 1992 governments undertook to develop and adopt national sustainable development strategies as a key component of implementing the goals of Agenda 21. Only partial progress was reported at the 2002 World Summit in Johannesburg, with uncertainty as to the effectiveness of those strategies that had been introduced. This paper describes a methodology for assessing a country
This paper discusses the 3D dosimetric consequences of radiotherapy delivery during two kinds of motion, (i) the respiratory motion by the patient and (ii) the motion by the gantry while rotating around the patient. Respiratory motion primarily compromises treatments in the thorax and abdomen regions. Several strategies to reduce respiratory motion effects have been developed or are under developm
Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.
Dynamic heterogeneity in lung ventilation is an important measure of pulmonary function and may be characteristic of early pulmonary disease. While standard indices like spirometry, body plethysmography, and blood gases have been utilized to assess lung function, they do not provide adequate information on regional ventilatory distribution nor function assessments of ventilation during the respira
Climate change is an important driver of range shifts and community composition changes. Still, little is known about how the responses are influenced by the combination of land use, species interactions and species traits. We integrate climate and distributional data for 131 butterfly species in Sweden and Finland and show that cumulative species richness has increased with increasing temperature
In 1909, Italian zoologist Daniele Rosa proposed a radical new evolutionary theory: hologenesis, or simultaneous, pan-terrestrial creation and evolution driven primarily by internal factors. Hologenesis was widely ignored or rejected outside Italy, but Swiss-French anthropologist George Montandon eagerly embraced and developed the theory. An ambitious careerist, Montandon’s deep investment in an o
Intermarriage with natives has the potential to enhance immigrant integration, as intermarried immigrants gain access to resources such as language skills, information about institutions and customs, and native networks. Due to these spillover effects, immigrants in intermarriages are more likely to be successful in the labour market. However, a positive relationship between intermarriage and econ
This article examines the relationship between theories of the ‘new’ public diplomacy and recent attemptsby foreign ministries in the United Kingdom, United States and Sweden to develop public diplomacystrategies for the early twenty-first century. It provides a summary of policy debates in each nation alongsideanalysis of the evaluation methods that have been designed to support them. The article
Disease modifying drugs for osteoarthritis (OA) that may halt or retard joint destruction and at the same time possibly improve symptoms are being developed and tested at various stages in clinical trials. This has, for at least two reasons, focused attention on the need for identification of patient groups at high risk for incident or progressive OA. First, well characterized such groups may be u
TPA is known to cooperate with an activated Ras oncogene in the transformation of rodent fibroblasts, but the biochemical mechanisms responsible for this effect have not been established. In the present study we used c-fos promoter-luciferase constructs as reporters, in transient transfection assays, in NIH3T3 cells to assess the mechanism of this cooperation. We found a marked synergistic interac
Reading methods for software inspections are used for aiding reviewers to focus on special aspects in a software artefact. Many experiments have been conducted for checklist-based reading and scenario-based reading concluding that the focus is important for software reviewers. This paper describes and evaluates a reading technique called usage-based reading (UBR). UBR utilises prioritised use case
