Search results

The thermotropic phase behaviour and phase structure of crystalline and non-crystalline n-tetradecyl-beta-D-maltoside (C(14)G(2)) and n-hexadecyl-beta-D-maltoside (C(16)G(2)) have been investigated by means of differential scanning calorimetry and X-ray techniques. Upon lyophilisation, both compounds form a solid, lamellar phase comprising disordered head groups and hexagonally packed alkyl chains

The thermophilic marine bacterium Rhodothermus marinus produces a modular family 10 xylanase (Xyn10A). It consists of two N-terminal family 4 carbohydrate binding modules (CBMs) followed by a domain of unknown function (D3), and a catalytic module (CM) flanked by a small fifth domain (D5) at its C-terminus. Several truncated mutants of the enzyme have been produced and characterised with respect t

Binary composite endpoints offer some advantages as a way to succinctly combine evidence from a number of related binary endpoints recorded in the same clinical trial into a single outcome. However, as some concerns about the clinical relevance as well as the interpretation of such composite endpoints have been raised, it is recommended to evaluate the composite endpoint jointly with the involved

A macroscopically oriented double diamond inverse bicontinuous cubic phase (Q(II)(D)) of the lipid glycerol monooleate is reversibly converted into a gyroid phase (Q(II)(G)). The initial Q(II)(D) phase is prepared in the form of a film coating the inside of a capillary, deposited under flow, which produces a sample uniaxially oriented with a < 110 > axis parallel to the symmetry axis of the sample

Natural killer (NK) cells are cytotoxic lymphocytes and play a vital role in controlling viral infections and cancer. In contrast to B and T lymphopoiesis where cellular and regulatory pathways have been extensively characterized, the cellular stages of early human NK cell commitment remain poorly understood. Here we demonstrate that a Lin(-)CD34(+)CD38(+)CD123(-)CD45RA(+)CD7(+)CD10(+)CD127(-) pop

The growth and ordering of {5,10,15,20-tetrakis(4-bromophenyl)porphyrinato}nickel(II) (NiTBrPP) molecules on the Au(111) surface have been investigated using scanning tunnelling microscopy, X-ray absorption, core-level photoemission, and microbeam low-energy electron diffraction. When deposited onto the substrate at room temperature, the NiTBrPP forms a well-ordered close-packed molecular layer in

Fennoscandia has a strong tradition in dendrochronology, and its large tracts of boreal forest make the region well suited for the development of tree-ring chronologies that extend back several thousands of years. Two of the world's longest continuous (most tree-ring chronologies are annually resolved) tree-ring width chronologies are found in northern Fennoscandia, with records from Tornetrask an

International Relations (IR) research is constantly undergoing change, both in reaction to real changes in international politics and to new patterns of and trends in cooperation and conflict, as well as to methodological innovations within the academy. In general the discipline of IR has paid extensive attention to the definition and dynamics of conflict, while in comparison fewer efforts have be

The yeast pathogen Candida glabrata is the second most frequent cause of Candida infections. However, from the phylogenetic point of view, C. glabrata is much closer to Saccharomyces cerevisiae than to Candida albicans. Apparently, this yeast has relatively recently changed its life style and become a successful opportunistic pathogen. Recently, several C. glabrata sister-species, among them clini

Hypoxia is an important factor in the hematopoietic stem cell (HSC) niche in the bone marrow, but whether it also plays a role in the regulation of fetal liver (FL) HSCs is unclear. Vascular endothelial growth factor A (VEGFA) is essential for adult HSC survival, and hypoxic induction of VEGFA in adult HSCs is required for proper function. Loss of hypoxia-regulated VEGFA expression increases the n

This is an overview paper that motivates and describes performed work done in the European Commission funded research project BASTION, which focuses on two critical problems of modern electronics: the No-Fault-Found (NFF) and CMOS ageing. New defect classes contributing to NFF have been identified, including timing related faults (TRF) at board level and intermittent resistive faults (IRF) at IC l

Animal tissue requires low-oxygen conditions for its maintenance. The need for low-oxygen conditions contrasts with the idea of an evolutionary leap in animal diversity as a result of expanding oxic conditions. To accommodate tissue renewal at oxic conditions, however, vertebrate animals and vascular plants demonstrate abilities to access hypoxia. Here, I argue that multicellular organisms sustain

Background: Despite the mutual benefit of the industry-academia partnership, the level of joint work is still low. For this reason, the interest in connecting research and practice has increased recently in the academic community. Objective: This research aims to design and apply approaches to improve the knowledge exchange between academic researchers and software engineering practitioners. Metho

Abstract in UndeterminedDiabetic foot complications result in huge costs for both society and the individual patients. Few reports on the health-economic consequences of diabetic foot infections have been published. In studies considering a wide societal perspective, costs of antibiotics were relatively low, whereas total costs for topical treatment were high relative to the total costs of foot in

The sand-steppe is a unique vegetation type almost exclusively found in eastern Scania. It is dominated by rare species such as Koeleria glauca, Festuca polesica, Phleum arenarium, Dianthus arenarius, Astragalus arenarius, Anthericum ramosum and Syntrichia ruraliformis. In 1994, the area covered by this vegetation was estimated to be 57 ha but in the present study only 20-30 ha were refound. Prere