Sertindole: efficacy and safety in schizophrenia
Sertindole is an antipsychotic drug with affinity for dopamine D, serotonin 5-HT2A and 5-HT2C, and alpha(1)-adrenoreceptors. Preclinical studies suggest that sertindole acts preferentially on limbic and cortical dopaminergic neurons and clinical trials have confirmed that sertindole is effective at a low cloparnine D-2 occupancy level. The active substance has a long half-life. Oral administration
