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Altered expression of cyclin E and the retinoblastoma protein influences the effect of adjuvant therapy in breast cancer
Kristallen i Mellanrummet
In the fall of 2007 a collective of artists in southern Sweden made waves for themselves by attempting to construct a rather unique ‘club-format’ unlike any other in the [then] current Swedish underground club scene. Guided mainly by a self-proclaimed ‘notion of confusion’ as its foundational principle, the collective behind Klubb Kristallen branded itself as an aspiring anti-club by seeking to ch
Inflammation, Plaque Vulnerability and Cardiovascular Risk
Acute cardiovascular events, most commonly caused by rupture of an atherosclerotic plaque, lie behind one third of all deaths worldwide. Atherosclerosis is an inflammatory disease of large and medium sized arteries driven by retention of lipid in the arterial wall. Inflammatory activity in the plaque is believed to be an important driving force behind plaque progression and rupture. However it is
Adaptations for stealth in the wing-like flippers of a large ichthyosaur
With their superficially shark-like appearance, the Mesozoic ichthyosaurs provide a classic illustration of major morphological adaptations in an ancestrally terrestrial tetrapod lineage following the invasion of marine habitats1, 2–3. Much of what is known about ichthyosaur soft tissues derives from specimens with body outlines4, 5–6. However, despite offering insights into aspects of biology tha
Adjuvant Hyperthermic Intraperitoneal Chemotherapy in Patients With Locally Advanced Colon Cancer (COLOPEC) : 5-Year Results of a Randomized Multicenter Trial
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has
Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction
Controlled trial of cervical cancer screening frequency among human-papillomavirus-vaccinated women
Higher serum free thyroxine levels are associated with increased risk of hip fractures in older men
String Intonation : Personal Expression and Pedagogical Challenges
Signal-Averaged ECG in the Diagnostic Workup for Arrhythmogenic Cardiomyopathy : Insights From the Nordic ARVC Registry
A burden of rare copy number variants in obsessive-compulsive disorder
Right ventricular dyssynchrony predicts outcome in pulmonary arterial hypertension when assessed in multiple cardiac magnetic resonance views
Tidally induced radial migration waves in Large Magellanic Cloud-like galaxies
Supergiant GCIRS 22 in the Milky Way nuclear star cluster : Revised alpha abundances
Context. The chemical abundances of alpha elements in Galactic Centre (GC) supergiants provide key insights into the chemical enrichment and star formation history of the Milky Way’s nuclear star cluster. Previous studies have reported enhanced alpha-element abundances, which raises questions about the chemical evolution of this unique region. Aims. We aim to reassess the alpha-element abundances