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ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells.
DynaReP: a discrete event simulation model for re-planning of software releases
Software release planning can be described as a process consisting of the following three phases: (i) strategic release planning, i.e., the assignment of features to subsequent releases; (ii) operational release planning, i.e., the allocation of resources to tasks within each individual release; and (iii) dynamic re-planning, i.e., the revision of plans in order to handle unexpected changes impose
Measurements of the binding force between the Helicobacter pylori adhesin BabA and the Lewis b blood group antigen using optical tweezers
Experimental evidence for sub-3-fs charge transfer from an aromatic adsorbate to a semiconductor
The ultrafast timescale of electron transfer processes is crucial to their role in many biological systems and technological devices. In dye-sensitized solar cells(1-4), the electron transfer from photoexcited dye molecules to nanostructured semiconductor substrates needs to be sufficiently fast to compete effectively against loss processes and thus achieve high solar energy conversion efficiencie
Thalidomide inhibits early atherogenesis in apoE-deficient mice
Modeling through drying of tissue-effect of pore size distribution on drying characteristics
A general model for through drying of tissue was developed based on the equations of continuity in combination with correlations for heat and mass transfer. The model incorporates different geometric descriptions together with corresponding heat and mass transfer correlations for flow through cylindrical conduits and flow through packed beds of cylindrical fibers. At low intensities, i.e., at low
Between Fall and Fall-Rise : Substance-Function Relations in German Phrase-Final Intonation Contours
Multimodal imaging in CABP4-related retinopathy
The Cosmic Origin of Fluorine : An Astronomer's View on Fluorine Synthesis
All fluorine atoms in fluoride compounds discussed in this book were synthesized in the stars or in stellar processes well before the solar system was formed some 4.6. billion years ago. The main cosmic production sites are, however, still elusive. This is not only because it is challenging to empirically determine the buildup of fluorine abundance in the universe over time, but also because of th
Intracavity double diode structures with GaInP barrier layers for thermophotonic cooling
Moderate elevation of extracellular potassium transiently inhibits regeneration of sensory axons in cultured adult sciatic nerves
HIV-1-neutralizing IgA detected in genital secretions of highly HIV-1-exposed seronegative women on oral preexposure prophylaxis
Demonstration of Sn-seeded GaSb homo- and GaAs-GaSb heterostructural nanowires
Who are "the parties"? Article 31 §3(c) and the "Principle of Systemic Integration" Revisited
Level crossing prediction with neural networks
A level crossing predictor or alarm system with prediction horizon k is said to be optimal if it, at time t detects that an upcrossing will occur at time t + k, with a certain high probability and simultaneously gives a minimum number of false alarms. For a Gaussian stationary process, the optimal level crossing predictor can be explicitly specified in terms of the predicted value of the process i
Colour change in the human histamine wheal made visible by LYYN: a technique to enhance colour differences.
Background: Colour differences in photographs can be enhanced using a digital image-processing technique called LYYN. Objective: To investigate colour changes in the histamine wheal after skin prick tests (SPTs). Methods: Histamine SPTs were performed on the forearm of six medical students, and the reactions of the skin were photographed every 2 min for 30 min. Colour differences in the photograph
Pilgrimstad revisited - a multi-proxy reconstruction of Early/Middle Weichselian climate and environment at a key site in central Sweden
Skåne, på rätt spår? En jämförande studie av de kostnads-nyttoanalyser som gjorts på de planerade spårvägsprojekten i Skåne
This study investigates the cost-benefit analyses (CBA) performed on the proposed tramway projects in three Swedish municipalities, Malmö, Lund and Helsingborg. The purpose is to determine the feasibility of these analyses and their adherence to economic theory as well as to the guidelines and recommendations provided for CBA by the Swedish Transport Administration. The study shows that the adher
